Prevalence and antimicrobial resistance of uropathogens in different inpatient wards

Szász, M.; Lehotkai, Nóra; Kristóf, Katalin; Szabó, Dóra; Nagy, K.

doi:10.1556/amicr.56.2009.4.7

Cited by 9 publications

(9 citation statements)

References 21 publications

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“…Several previous studies have discussed its signifi cance, especially in the development of acute cystitis in young females, and more is being discovered about its pathogenic properties, including resistance to antibiotics [10]. The data we collected within the tested period show that there is, in fact, a relation between the type of uropathogen, and the agegroup and gender which that uropathogen affects.…”

Section: Discussionmentioning

confidence: 83%

Does Staphylococcus Saprophyticus Cause Acute Cystitis only in Young Females, or is there more to the Story? A One-Year Comprehensive Study Done in Budapest, Hungary

Adeghate¹,

Juhász²,

Pongrácz³

et al. 2016

Acta Microbiologica et Immunologica Hungarica

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Staphylococcus saprophyticus is a well-known urinary pathogen in acute cystitis in young females. We completed a retrospective overview of the distribution of urinary tract infections (UTIs) occurring in 2014, at Semmelweis University hospitals and at Heim Pál Children's Hospital. Six age-groups (ages 0-100) were examined, with the frequency of S. saprophyticus in females being: 0.1% (0-4), 0.7%, (5-15), 7.4% (16-24), 1.2% (25-39), 0.4% (40-59) and 0.1% (60-100), and S. saprophyticus being the 3 rd most common pathogen in females aged 16-24. In males, S. saprophyticus was only isolated from those aged 5-15. Seasonal distribution of UTIs caused by S. saprophyticus showed that most infections occurred during the months of January, June, August and November. Antibiotic-resistance rates of amoxicillin, clindamycin, doxycycline, erythromycin, gentamicin and sulfamethoxazole-trimethoprim varied as follows: 0.9%, 32.7%, 19.6%, 34.6%, 0.9% and 0.9%, respectively. Thirty randomly selected samples were analysed by pulsed-fi eld gelelectrophoresis, and 28 different genotypes were identifi ed. S. saprophyticus is involved in the pathogenesis of acute cystitis not only in young females, but also in other age-groups, and in young males as well. We did not fi nd any signifi cant seasonal occurrence in S. saprophyticus-caused UTIs. The infective strains were genetically diverse. Antibiotic-resistance does not pose any issue as of yet.

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Section: Discussionmentioning

confidence: 83%

Does Staphylococcus Saprophyticus Cause Acute Cystitis only in Young Females, or is there more to the Story? A One-Year Comprehensive Study Done in Budapest, Hungary

Adeghate¹,

Juhász²,

Pongrácz³

et al. 2016

Acta Microbiologica et Immunologica Hungarica

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“…Among the Enterococcus spp, Enterococcus faecalis was 84.6% (11/13) and E. faecium accounted for 15.3% (2/13). [22122]…”

Section: Discussionmentioning

confidence: 99%

“…[1] It is also the most common nosocomial infection, accounting for up to 40% of all nosocomial infections. [2] UTI is particularly responsible for discomfort in elderly patients, representing a risk of bacteremia, septic shock, respiratory distress syndrome and death. [3] Even though several different microorganisms can cause UTI, including protozoan parasites, fungi and viruses, bacteria are the major causative organisms.…”

Section: Introductionmentioning

confidence: 99%

Hospital and community isolates of uropathogens and their antibiotic sensitivity pattern from a tertiary care hospital in North West India

Sejben

Sharma

Jain

et al. 2014

Ann Med Health Sci Res

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Background:Urinary tract infection remains one of the most common infections, both in the community and in the hospital. The causative pathogen profile varies from region to region, but Escherichia coli (E. coli) remains the most common causative pathogen. The sensitivity of uropathogens to different drugs varies in different areas, and changes with time. This necessitates periodic studies of the causative uropathogens and their antibiotic sensitivity pattern.Aim:To investigate the profile of common uropathogens and assess their antibiotic sensitivity patterns to commonly used antimicrobial agents.Materials and Methods:Analysis of all urine specimens submitted for culture and sensitivity was carried out over a 1-year period in a tertiary care hospital in North West India. Urine culture was done by a semi-quantitative method. Antibiotic sensitivity was done on bacterial isolates according to the Clinical and Laboratory Standards Institute CLSI guidelines for disc diffusion susceptibility test. Data was analysed for significance using Chi square test.Results:Of a total of 6348 urine specimens received over the 1-year study period, 41.8% (2653) of the urine samples were culture positive. The most common bacterial isolate was E. coli (45.7%, 1103/2412), followed by Coagulase-negative Staphylococci (18.6%, 449/2412) and Klebsiella species (8.3%, 199/2412). The Candida species’ isolation rate was 10.3% (277/2689). The uropathogens displayed a very high level of resistance to fluroquinolones 70.3% (1084/1542)[Inpatient Department (IPD) – 70.5%(572/812), Outpatient Department (OPD) – 70.2%(512/730)] and cephalosporins 75.1%(1158/1542)[IPD – 73.8%(599/812), OPD – 76.6%(559/730)], whereas resistance to nitrofurantoin 19.8%(305/1542) [ IPD – 23.9%, OPD – 15.2%(111/730)], amikacin 32.4%(573/1769) [IPD – 36.1%(235/934), OPD – 28.1%(235/835)] and cephoperazone + sulbactam combination 22%(349/1583) [IPD – 26.2%(244/914), OPD – 15.8%(105/669)] was low.Conclusion:Empiric selection of antimicrobial agents should be based on the antibiotic sensitivity pattern of the uropathogens prevalent in that area, which is derived from epidemiological studies carried out in that environment.

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“…[1] It is also the most common nosocomial infection, accounting for up to 40% of all nosocomial infections. [2] UTI is particularly responsible for discomfort in elderly patients, representing a risk of bacteremia, septic shock, respiratory distress syndrome and death. [3] Even though several different microorganisms can cause UTI, including bacteria, protozoan parasites, fungi and viruses.…”

Section: Introductionmentioning

confidence: 99%

Clinical Utility of Antibiotic against Uropathogen Isolated at a Tertiary Care Hospital of Dhaka City

Khanam¹,

Sharif²,

Sharmin³

et al. 2018

AJMR

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Background: The antibiotic sensitivity pattern of uropathogenic bacteria is varied with different frequency. Objective: The purpose of the study was to determine the pattern of antibiotic sensitivity against uropathogens isolated from a tertiary care hospital of Dhaka City. Methodology: A cross-sectional study was conducted in the Department of Microbiology at Shaheed Suhrawardy Medical College, Dhaka, Bangladesh during period of January 2016 to December 2016. Among 307 consecutive urine samples were collected from patients of UTI in the microbiology laboratory. Samples were mid-stream urine specimens obtained by clean catch method received from various outpatient departments and inpatient wards were transported to the microbiology laboratory in sterile leak proof container were processed immediately. Bacteria were isolated and identified by standard laboratory procedure. Results: Of the 307 urine samples processed 170(55.4%) gave significant growth of pathogens. The prevalence of UTI is high among females (58.2%) than males (41.8%). The commonest isolates were Escherichia coli (71.2%), Pseudomonas (12.4%), Staphylococcus aureus (10.6%), Acinotobactor (4.1%) and Klebsiella (1.8%). Majority (92.4%) of (uropathogens) isolates were found to be MDR. Conclusion: The study revealed that E. coli is the predominant uropathogens of UTIs.

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Prevalence and antimicrobial resistance of uropathogens in different inpatient wards

Cited by 9 publications

References 21 publications

Does Staphylococcus Saprophyticus Cause Acute Cystitis only in Young Females, or is there more to the Story? A One-Year Comprehensive Study Done in Budapest, Hungary

Does Staphylococcus Saprophyticus Cause Acute Cystitis only in Young Females, or is there more to the Story? A One-Year Comprehensive Study Done in Budapest, Hungary

Hospital and community isolates of uropathogens and their antibiotic sensitivity pattern from a tertiary care hospital in North West India

Clinical Utility of Antibiotic against Uropathogen Isolated at a Tertiary Care Hospital of Dhaka City

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