Prevalence and associated factors of baseline anemia among cervical cancer patients in Tikur Anbesa Specialized Hospital, Ethiopia

Abstract

Background Almost one patient with cancer in two is anemic. About 40 to 64% of cervical cancer patients are anemic at time of presentation. The rate of anemia increases with the use of chemotherapy, radiotherapy, hormonal therapy and associated with poorer treatment outcome and quality of life. Therefore, the aim of this study was to assess prevalence and associated factors of baseline anemia among cervical cancer patients in Tikur Anbesa Specialized Hospital (TASH), Ethiopia. Methods Institutional based cross-sectional study was done from March to April 2019 at TASH cancer center. Data were collected from patient’s chart using structured checklist and analyzed using Stata14.2. Binary logistic regression model was used to identify covariates which affected the outcome variable. Result This is a 3-years retrospective study from 2014 to 2016. The prevalence of baseline anemia among cervical cancer patients was 50.95%. Being stage IV [AOR = 2.38, 95% CI (1.21–4.67)], having comorbidity [AOR = 3.32, 95% CI (2.25–4.90)] and using substances (patients who used one, two or all of the three substances (cigarate, chat and alcohol)) [AOR = 2.03, 95% CI (1.21–3.41)] significantly increased the occurrence of anemia while being divorced [AOR = 0.6, 95% CI (0.36–0.98)] decreased the occurrence of anemia in the current study. Conclusion The prevalence of baseline anemia was high in the current study compared to other literatures. Significant factors of baseline anemia of cervical cancer in the current study were advanced stage (stage IV), presence of comorbidity, substance usage and being divorced (protective). The authors recommend that it is better to give special attention to those patients with the stated factors that could interfere treatment outcome.

Clinical and non-clinical determinants of cervical cancer mortality: A retrospective cohort study in Lagos, Nigeria

“…Anemia was found in over four-fifths of CCa patients in our study. This estimate was significantly higher relative to earlier reports in Ethiopia (51.2%), Kenya (56.5%), Northern Nigeria (51%) and Korea (36.4%) ( 11 , 14 , 32 , 33 ). In the United States, however, Hufnagel and colleagues ( 34 ) found up to 64% of gynecologic cancer (including CCa) patients developed anemia within six months of their diagnosis while the European Cancer Anemia Survey (ECAS) found up to 68% prevalence of anemia among European cancer patients during a 6-month survey period ( 35 ).…”

Management Practice and Drug Related Problems and Its Contributing Factors Among Cervical Cancer Patients at Oncologic Center in Ethiopia: A Hospital-Based Retrospective Study

“… 29 Another study also reported the worst results, in which 69% of participants were diagnosed with stage IV cervical cancer. 40 A study conducted at Kenyatta National Hospital also showed that 44.4% and 35.8% of the study population had stage II and stage III cervical cancer, respectively. 21 On the contrary, studies done by Chen et al 41 and Getahun et al 33 reported that slightly more than half (~̴ 53%) of participants were diagnosed with early stage (stage I) cervical cancer.…”

Determinants of Mortality among Cervical Cancer Patients Attending in Tikur Anbessa Specialized Hospital, Ethiopia: Institutional-Based Retrospective Study

“…Vaccination against human papillomavirus and regular screening should be introduced and expanded to decrease morbidity and subsequent costs in both human lives and other resources [ 12 ]. In addition, early diagnosis of cervical cancer and prevention of anemia in cervical cancer patients can reduce the mortality rate of the disease [ 13 , 14 ]. Since there is limitation of data about determinants of mortality among cervical cancer patients in Ethiopia, this research will fill the gaps and be used as the base line information by health policy makers and administrators in the country.…”