Prevalence and associated factors of hyperuricemia among urban adults aged 35–79 years in southwestern China: a community-based cross-sectional study

Abstract

Hyperuricemia is prevalent throughout the world. However, a well-designed large-scale epidemiological investigation of hyperuricemia in southwestern China is lacking. A regional representative sample of 10,141 participants were included using multistage, stratified sampling in Chengdu and Chongqing from September 2013 to March 2014. Hyperuricemia was defined as the self-reported of the doctor's diagnosis of hyperuricemia, or serum uric acid > 420 μmol/L in men or serum uric acid > 360 μmol/L in women. The overall age- and sex-standardized prevalence of hyperuricemia among adults aged 35–79 years was 13.5%. Compared with women, the prevalence of hyperuricemia in men was higher (17.3% versus 10.0%). Hypertension, hyperlipidemia, overweight or obesity, central obesity were associated with an increased risk for hyperuricemia both in men and in women. Married men and women were not susceptible to hyperuricemia. Current cigarette smoking was an associated risk factor of hyperuricemia only in women. Hyperuricemia has become a major health problem among urban adults aged 35–79 years in southwestern China, and special attention should be paid to men. Comorbidities associated with hyperuricemia and causality worth further investigation.

Serum Uric Acid Levels and Metabolic Indices in an Obese Population: A Cross-Sectional Study

“…The risk of sudden death in obese patients is quite high, even in the absence of organic heart disease, which may be associated with metabolic syndrome. 13 It has been shown by various prospective studies that HUA is an independent risk factor of obesity. 2 Compared with subjects with normal weight, obese subjects have significantly higher levels of SUA and components of metabolic syndrome.…”

Association of self-reported snoring and hyperuricaemia: a large cross-sectional study in Chongqing, China

“… 39 The difference may be explained by the different lifestyles and economic level in the two different areas, which are also closely related to hyperuricaemia. 40 Our determined prevalence was also slightly higher than that in southwest (Chengdu and Chongqing) China hyperuricaemia survey, which showed that the prevalence of hyperuricaemia was 13.5% in 2013–2014 10 . This indicates that we should pay more attention to hyperuricaemia due to the prevalence is increasing with the improvement of economic level and lifestyles changes.…”

“…Meanwhile, various major risk factors for hyperuricaemia have been found, such as low economic status,9 obesity10and smoking,11 and some studies have found a link between sleep-disordered breathing and hyperuricaemia 12–17. However, the association of snoring and hyperuricaemia has been studied much less extensively.…”

Cross-sectional Study on the Association Between Hyperuricemia and Other Metabolic Diseases

“…While a cross-sectional study in Thailand showed the prevalence of HUA was 10.6% (18.4% in men and 7.8% in women) [10], which is higher than in the US, obviously. A community-based cross-sectional study showed the prevalence of HUA among adults aged 35-79 years was 13.5% (17.3% in men and 10.0%in women) in southwestern China [11]. Meta-analysis indicated that the pooled prevalence of HUA was 17.4% (ranged from 15.5 to 24.6% by regions) among the general population in mainland China, which had become another common metabolic disease after diabetes [12].…”