Prevalence and characteristics of early-onset type 2 diabetes in Mexico

Aguilar-Salinas, Carlos A.; Rojas, Rosalba; Gómez-Pérez, Francisco J.; García, Eduardo García; Valles, Victoria; Ríos-Torres, Juan M; Franco, Aurora; Oláiz, Gustavo; Sepúlveda, Jaime; Rull, Juan

doi:10.1016/s0002-9343(02)01314-1

Cited by 57 publications

(36 citation statements)

References 33 publications

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“…(16) The present study was done in 65 young diabetics. In this age group, Type 2 diabetes was more common than Type 1 (76.9 Vs. 23.1%), which was comparable with the study done by AguilarSalinas et al (17) In the present study there was a male preponderance (60%) in Type 1 and female preponderance (66%) in Type 2 diabetes mellitus which were comparable with Aguilar-Salinas et al (17) (52%) and Antonio perez et al (18) (54%) and studies respectively.…”

Section: Age(yrs)supporting

confidence: 91%

The Association Between Lipid Profile and Waist to Hip Ratios in Type - 1 and Type - 2 Diabetic Patients – A Comparative Study

S¹,

Atluri²,

Rao³

et al. 2015

jemds

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BACKGROUND:Diabetes is frequently associated with dyslipidemia and Obesity is one of the major risk factors. Anthropometrical measurements like BMI and WHR were used to rule out obesity and are more practical both in the clinical practice and epidemiological studies. Dyslipidemia remains largely under diagnosed and neglected in high risk populations in both Type-1 and Type-2 diabetes. To this purpose we have evaluated the lipid profiles in young diabetic patients (Type-1 and Type-2) to correlate them with their glycemic status, body mass index and waist-hip ratio in comparison with control subjects. METHODS: This comparative study was conducted in 65 diabetic and 30 non-diabetic patients, who had attended either as inpatients or outpatients to medicine or endocrinology departments of tertiary care hospital at Coastal Andhra Pradesh during the period from December 2006 to October 2008. Complete history was obtained from all these patients and a thorough physical examination was done. Their height, weight, waist and hip circumferences were measured and evaluated glycemic status and lipid profiles biochemically. The data was analyzed statistically and expressed results in mean, standard deviation, unpaired t test, chi-square test RESULTS: The total number of patients studied was 65 diabetics in which Type-1 DM were 15 and Type-2 DM was 50; controls were: 30 in number. In Type-1 BMI of <18.5 (mean=16.60±0.91), whereas in Type 2, 56% of patients had a BMI of ≥25 with a mean of 25.44±4.23. In Type-2 DM, among 22 patients with BMI <25,17(77.27%) had dyslipidemia and among 28 patients with BMI >25, 28(100%) had dyslipidemia. In Type-2 DM, out of 50 patients 32 64%) patients had high W/H ratio and 18(36%) patients had normal W/H ratio. In Type-2 DM TC, TG, LDL-C, were elevated and HDL-C was reduced in Type 2 compared to controls which were statistically significant. Out of 18 well controlled patients 13(72.22%) had dyslipidemia and among 32 poorly controlled and 32 patients had (100%) dyslipidemia. CONCLUSION: The present study suggests that dyslipidemia was more prevalent in diabetics and was associated with poor glycemic status. It was also found that dyslipidemia was more prevalent in over weight and obese patients with Type-2 DM than non-obese patients and Type-1 Diabetics. In Type 2 DM, dyslipidemia was associated with an abnormal WHR than normal WHR.

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Section: Age(yrs)supporting

confidence: 91%

The Association Between Lipid Profile and Waist to Hip Ratios in Type - 1 and Type - 2 Diabetic Patients – A Comparative Study

S¹,

Atluri²,

Rao³

et al. 2015

jemds

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“…[15][16][17][18][19] Las estrategias de prevención implementadas a escala poblacional en países con elevado riesgo que logren modificar estilos de vida -en particular en la dieta, actividad física y tabaquismo-pueden ser altamente costo efectivas al reducir la aparición de la diabetes y retrasar la progresión de la misma. México tiene condiciones de alto riesgo, por lo que recientemente se han impulsado políticas intersectoriales relacionadas con la salud alimentaria y con ello combatir uno de los más importantes factores de riesgo, la obesidad.…”

Section: S130unclassified

Diabetes mellitus en México. El estado de la epidemia

Gutiérrez²,

2013

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Objetivo. Estimar la magnitud del reto de la diabetes en México y presentar propuestas de políticas públicas para su atención. Material y métodos. Análisis descriptivo de la información sobre diagnóstico previo de diabetes en adultos y adolescentes, de la Encuesta Nacional de Salud y Nutrición 2012 (ENSANUT 2012). Resultados. De los adultos en México, 9.17% ha recibido un diagnóstico de diabetes, con resultados heterogéneos entre estados: de 5.6% en Chiapas a 12.3% en el Distrito Federal. Del total de diabéticos, 46.95% reportó también diagnóstico de hipertensión, 4.47% antecedente de infarto del corazón y 54.46%, antecedentes familiares de diabetes. De los adolescentes, 0.68% ha sido ya diagnosticado con diabetes. Conclusiones. La gravedad de la epidemia de diabetes, así como el hecho de que se trata de una enfermedad prevenible, llama a fortalecer las estrategias para hacerle frente. El impacto que tiene sobre la calidad de vida de las personas que la padecen la convierte en un área prioritaria para el sector salud.

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“…BMI was used instead of waist circumference because only the distribution of the former was available (National Survey of Chronic Diseases 1992-1993) (15)(16)(17)(18). Our definition is based on the decile distribution of the variables: 1 point is given per decile.…”

Section: Methodsmentioning

confidence: 99%

“…Hyperinsulinemia was defined as a fasting insulin concentration Ն21 U/ml; this value corresponds to the 75th percentile in Mexican adults (17). The original (6) and the updated NCEP III criteria (23) were applied for the diagnosis of the metabolic syndrome.…”

Section: Definitionsmentioning

confidence: 99%

Design and Validation of a Population-Based Definition of the Metabolic Syndrome

Aguilar-Salinas

Rojas

González‐Villalpando³

et al. 2006

Diabetes Care

Self Cite

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OBJECTIVE -The National Cholesterol Education Program (NCEP) definition of the metabolic syndrome was modified to be described as a continuous variable and adapted to the characteristics of a Hispanic population.RESEARCH DESIGN AND METHODS -Age/sex population percentiles for every component of the NCEP criteria were included in this approach using population-based data from a Mexican nationwide survey (2,158 subjects). One point was given per decile for every component. The total number of points accumulated was used to classify subjects. The predictive power for incident diabetes was evaluated using the 7-year follow-up results of the Mexico City Diabetes Study.RESULTS -Our population-based method had a significantly better prognostic power compared with the original and the updated NCEP definitions (area under the receiver operating characteristic curve 0.746 vs. 0.697 and 0.723, respectively, P Ͻ 0.05). Using individuals with Յ1 component of the NCEP definition as reference, the odds ratio was greater in the upper quartile of the points scale (Ն39 points) (12.71 [95% CI 5.67-28.49]) compared with that calculated for the original (9.52 [4.69 -19.31]) and the updated (11.14 [5.33-23.30]) NCEP criteria. The major advantage of our approach is the detection of subjects at the extremes of the range of diabetes risk and the ability to estimate this risk as a continuum.CONCLUSIONS -Our method adapts the NCEP criteria to the characteristics of a Hispanic population. It improves the predictive power of the NCEP criteria for future diabetes.

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Prevalence and characteristics of early-onset type 2 diabetes in Mexico

Cited by 57 publications

References 33 publications

The Association Between Lipid Profile and Waist to Hip Ratios in Type - 1 and Type - 2 Diabetic Patients – A Comparative Study

The Association Between Lipid Profile and Waist to Hip Ratios in Type - 1 and Type - 2 Diabetic Patients – A Comparative Study

Diabetes mellitus en México. El estado de la epidemia

Design and Validation of a Population-Based Definition of the Metabolic Syndrome

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