Prevalence and determinants of allergic diseases in a Congolese population

Nyembue, T. D.; Jorissen, Mark; Hellings, Peter W.; Muyunga, Christophe; Kayembe, Jean Marie

doi:10.1002/alr.21017

Cited by 19 publications

(20 citation statements)

References 25 publications

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“…The environmental exposure was similar in both urban and peri-urban area in this survey, consisting mainly of the presence of trees and flowers in the compound, proximity of industries or factories for outdoor and cockroaches, mice/rats, cats for indoor pollution as in previous studies [20] and even in that by Nyembue et al in 2012, in the same town [21]. The latter identified mainly Dermatophagoides pteronyssinus and cockroach in the community, using prick-tests.…”

Section: Discussionsupporting

confidence: 76%

“…ISAAC Phase III showed a 7.5% prevalence in individuals with asthmatic symptoms in Kinshasa [6, 16–17]. A more recent study by Nyembue and al., among individuals aged from five to 83 years old, reported a prevalence of declared respiratory symptoms of 15.4% in Kinshasa in 2012 [21]. …”

Section: Introductionmentioning

confidence: 99%

“…The exact causes of the increased asthma prevalence are still poorly understood but several hypotheses are described [21], many of which refer to changing environmental exposure [22–25]. ISAAC Phase one illustrated different asthma symptoms prevalence varying between 20-fold and 60-fold in populations with similar genetic or ethnic background, emphasizing the role of environmental risk factors in the increasing prevalence of the disease worldwide [26].…”

Section: Introductionmentioning

confidence: 99%

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Prevalence and determinants of asthma in adults in Kinshasa

et al. 2017

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BackgroundEpidemiological data on asthma among adults in sub-Saharan Africa are sparse.ObjectiveTo determine the prevalence of and factors associated with asthma among adults in Kinshasa.MethodsA previously validated asthma questionnaire was administered to an adult population aged ≥18 years in urban and peri-urban suburbs of Kinshasa. A random stratified multi-stage sampling plan was used to select the study participants. Logistic regression was used to identify factors associated with asthma.ResultsThe mean age of respondents was 36.7 (SD 15.36) years, 75% lived in an urban environment, and 57% were women. The prevalence of asthma-ever was 6.9% (95% CI: 5.4–8.4). Among asthmatic patients, intermittent asthma was estimated at 75.7% and severe asthma at 9.3%. Family atopy (OR: 3.97; 95% CI: 2.42–6.50; p<0.001), and the presence of a cat in the house (OR: 1.82; 95% CI: 1.01–3.28; p = 0.045) were associated with self-reported asthma.ConclusionAsthma is relatively frequent in adults in Kinshasa, a prevalence similar to those reported elsewhere in Africa. Family atopy and the presence of a cat in the house could be the most common determinants to be confirmed with national survey in order to design guidelines for the control of asthma.

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Section: Discussionsupporting

confidence: 76%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Prevalence and determinants of asthma in adults in Kinshasa

et al. 2017

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“…In the present study the point prevalence of allergic rhinitis at Bugando Medical Centre was 14.7%. This prevalence is comparable to 13.7%,13% found in Kinshasa [37] Nairobi Kenya [30] respectively. Higher prevalence of allergic rhinitis have been reported in African countries such as 29.6% in Nigeria [29] and more than 30% in Cape Town South Africa [11].…”

Section: Discussionsupporting

confidence: 73%

Allergic rhinitis and its associated co-morbidities at Bugando Medical Centre in Northwestern Tanzania; A prospective review of 190 cases

Said

Mchembe

Chalya

et al. 2012

BMC Ear Nose Throat Disord

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BackgroundAllergic rhinitis is one of the commonest atopic diseases which contribute to significant morbidity world wide while its epidemiology in Tanzania remains sparse. There was paucity of information regarding allergic rhinitis in our setting; therefore it was important to conduct this study to describe our experience on allergic rhinitis, associated co-morbidities and treatment outcome in patients attending Bugando Medical Centre.MethodsThis was descriptive cross-sectional study involving all patients with a clinical diagnosis of allergic rhinitis at Bugando Medical Centre over a three-month period between June 2011 and August 2011. Data was collected using a pre-tested coded questionnaire and analyzed using SPSS statistical computer software version 17.0.ResultsA total of 190 patients were studied giving the prevalence of allergic rhinitis 14.7%. The median age of the patients was 8.5 years. The male to female ratio was 1:1. Adenoid hypertrophy, tonsillitis, hypertrophy of inferior turbinate, nasal polyps, otitis media and sinusitis were the most common co-morbidities affecting 92.6% of cases and were the major reason for attending hospital services. Sleep disturbance was common in children with adenoids hypertrophy (χ2 = 28.691, P = 0.000). Allergic conjunctivitis was found in 51.9%. The most common identified triggers were dust, strong perfume odors and cold weather (P < 0.05). Strong perfume odors affect female than males (χ2 = 4.583, P = 0.032). In this study family history of allergic rhinitis was not a significant risk factor (P =0.423). The majority of patients (68.8%) were treated surgically for allergic rhinitis co morbidities. Post operative complication and mortality rates were 2.9% and 1.6% respectively. The overall median duration of hospital stay of in-patients was 3 days (2 – 28 days). Most patients (98.4%) had satisfactory results at discharge.ConclusionThe study shows that allergic rhinitis is common in our settings representing 14.7% of all otorhinolaryngology and commonly affecting children and adolescent. Sufferers seek medical services due to co-morbidities of which combination of surgical and medical treatment was needed. High index of suspicions in diagnosing allergic rhinitis and early treatment is recommended.

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“…Although the rising incidence of allergic disease in Western countries has been well documented, less is known about the incidence of allergic disease in Africa. Nyembue et al performed a very well designed study to evaluate the prevalence and determinants of allergic disease in the Congolese population of Kinshasha (page 285-293) 9 . As in other studies, they demonstrate an increased of allergic dieases with active smoking, the presence of cockroach and the use of straw mattresses, as well as higher incidence of rhinoconjunctivitis in the urban population.…”

mentioning

confidence: 99%