Prevalence and Forms of Congenital Anomalies in Twins Born in Pomeranian District During the Period from 1.07.1997 to 31.12.1998

Zimoń, Tomasz; Walczak, Mieczysław; Fydryk, J; Materna‐Kiryluk, Anna; Mejnartowicz, Jan P.; Latos‐Bieleńska, Anna; Ronin-Walknowska, Elżbieta; Czajka, Ryszard; Chosia, Maria; Gawrych, Elżbieta; Baryła-Pankiewicz, Elżbieta; Zajączek, Stanisław; Rudnicki, Jacek; Hulak, A; Chrystyniak, H; Romanowski, A; Staroniewska, I

doi:10.1017/s0001566000000180

Cited by 6 publications

(5 citation statements)

References 6 publications

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“…Our findings confirm earlier studies reporting a higher rate of total congenital anomalies in twins compared with singletons (Myrianthopoulos, 1976;Luke and Keith, 1990;Spellacy et al, 1990;Kato and Fujiki, 1992;Doyle, 1996;Zimo et al, 1998;Jaikrishan et al, 1999;Mastroiacovo et al, 1999;Li et al, 2003). Some studies found that the total rate of anomalies did not differ significantly between twins and singletons (Windham and Bjerkedal, 1984;Ghai and Vidyasagar, 1988;Little and Nevin, 1989a;Doyle et al, 1991;Ramos-Arroyo, 1991;Campana and Roubicek, 1996); however, some specific major anomalies were significantly more common in twins than in singletons (Windham and Bjerkedal, 1984;Doyle et al, 1991).…”

Section: Discussionsupporting

confidence: 90%

Congenital anomalies in twins: a register-based study

2008

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Section: Discussionsupporting

confidence: 90%

Congenital anomalies in twins: a register-based study

2008

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“…Previous studies have shown that monozygotic (identical) twins are at a higher risk of birth defects (Myrianthopoulos, 1975; Kato and Fujiki, 1992; Zimon et al, 1998; Mastroiacovo et al, 1999). Some studies found no significant difference in the overall birth defect rate between singletons and twins (Windham and Bjerkedal, 1984; Doyle et al, 1990; Ramos‐Arroyo, 1991; Campana and Roubicek, 1996; Nazer et al, 1999).…”

Section: Discussionmentioning

confidence: 99%

“…It has been shown that children from multiple births are at increased risk for preterm birth, low birth weight, long‐term disability, and early death (Doyle, 1996; MMWR, 1999; Tough et al, 2000). Previous studies also suggest that children from multiple births might be at higher risk for birth defects (Doyle et al, 1990; Kato and Fujiki, 1991; Zimon et al, 1998; Mastroiacovo et al, 1999; Doyle, 1996). Limited studies further address the association of multiple births and birth defects.…”

Section: Introductionmentioning

confidence: 95%

Increased risk of birth defects among children from multiple births

Ford

Meister

et al. 2003

Birth Defects Research

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“…Currently EUROCAT collects data from 43 registers in 20 states covering 29 % of European birth population (9)(10). In spite of efforts, the data on the incidence of congenital birth defects still do not exist in many countries (11)(12)(13)(14). On the other hand, according to the latest research in the Netherlands, the validity of the whole country register of the Dutch Association for Cleft Palate and Craniofacial Anomalies was very good (15).…”

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The incidence of cleft lip and palate in the Czech Republic in 1994–2008

Urbanová¹,

Koťová²,

Vankova³

2013

BLL

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Objective: To determine the incidence of nonsyndromic cleft lip and/or palate in the Czech Republic among infants born during 1994 -2008 as well as to defi ne the ratio per live births and sex ratios. Another aim was to determine whether there was any trend in the incidence in this time period. Design: Retrospective study. Setting: Prague Center for the Treatment of Congenital Facial Anomalies. Material and methods: Data were collected from the National Birth Defects Register (Institute of Health Information and Statistics), the Czech Statistical Offi ce and the Czech Health Statistics Yearbooks. The incidence, ratios per live births and sex differences were calculated. Possible trends in the data series were investigated. Results: Totally 2417 infants with a cleft defect were found among 1 471 789 newborns in time period 1994-2008. The overall incidence was 1.64 per 1000 live births or 1 in 600 live births. The incidence of cleft lip was 0.39/1000, the incidence of cleft palate was 0.68/1000 and the incidence of cleft lip and palate was 0.57/1000. The ratio per live births was 1 in 2648 in cleft lip, 1 in 1801 in cleft lip and palate and 1 in 1505 in cleft palate. The incidence was much higher among male babies in cleft lip patients (male to female ratio 2.07) and in patients with cleft lip and palate (males to females ratio 1.85). The male to female ratio in cleft palate newborns was 0.92. No traceable trend was found in the incidence. Conclusions: In the Czech Republic, every year approximately 170 infants with cleft lip and/or palate were born, the incidence was 1.64 per 1000 live born infants during considered period. Males were affected more frequently with isolated cleft lip and cleft lip and palate, on the other hand, in cleft palate patients, there was a slight dominance of females. Further long-term studies are necessary in order to elucidate reasons of the oscillations in incidence of cleft anomalies, to identify possible teratogens and to give a starting indication for planning health service resource requirements for this group of affected infants (Tab. 3, Fig. 4

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Prevalence and Forms of Congenital Anomalies in Twins Born in Pomeranian District During the Period from 1.07.1997 to 31.12.1998

Cited by 6 publications

References 6 publications

Congenital anomalies in twins: a register-based study

Congenital anomalies in twins: a register-based study

Increased risk of birth defects among children from multiple births

The incidence of cleft lip and palate in the Czech Republic in 1994–2008

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