Prevalence and intensity of infections of Ascaris lumbricoides and Trichuris trichiura and associated socio-demographic variables in four rural Honduran communities

Hm, Smith; DeKaminsky, RG; Niwas, S; Soto, RJ; Pe, Jolly

doi:10.1590/s0074-02762001000300004

Cited by 61 publications

(52 citation statements)

References 34 publications

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“…7,8,[20][21][22][23] The reason for this is unclear, but it may be explained by the similar route of infection for the two parasites. 15 In our study at the end of stool examination, the egg reduction rate (ERR) of Ascaris lumbricoides and Trichuris trichiura were 100% and 97.9% in combination group and 99.9% and 98.1% in mebendazole group. Legesse et al 24 used mebendazole 2 x 100 mg for 3 consecutive days and obtained ERR of 99.8 and 92.3% for A. lumbricoides and T. trichiura.…”

Section: Discussionmentioning

confidence: 58%

Treatment of intestinal helminthiasis: mebendazole only or mebendazole-pyrantel pamoate?

Dalimunthe¹,

Siregar²,

Lubis³

et al. 2007

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Background Although intestinal helminthiasis causes highmorbidity and has a negative impact on children’s growth anddevelopment, the efficacy of antihelmintics for multiplehelminthiasis in mass treatment is still doubtful.Objective To compare the efficacy of single dose mebendazoleand a combination of pyrantel pamoate and mebendazole for thetreatment of multiple infections due to Ascaris lumbricoides,hookworm, and Trichuris trichiura.Methods Subjects were elementary school students in Suka Village,Tiga Panah subdistrict, North Sumatera. They were randomizedto either receive mebendazole (M Group) or mebendazole-pyrantel pamoate group (MP Group). Stool examinations wereperfomed on each subjects on day 7, 14, 21, and 28 after treatment.Analyses were perfomed by using chi-squared and Mann-WhitneyU tests.Results The prevalence of intestinal helminthiasis was 95.4%. T.trichiura (88.7%) was the most common cause of infection followedby A. lumbricoides (79.5%), and hookworm (3.1%). Two hundredthirty nine (76.8%) children had multiple infections. Althoughthe egg reduction rate of intestinal helminthiasis in thecombination group was faster than that of the mebendazole group,there was no significant difference in the cure rate of both groups.Conclusion A single dose of mebendazole is preferred for masstreatment of multiple intestinal helminthiasis infections.

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Section: Discussionmentioning

confidence: 58%

Treatment of intestinal helminthiasis: mebendazole only or mebendazole-pyrantel pamoate?

Dalimunthe¹,

Siregar²,

Lubis³

et al. 2007

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“…Rural conditions of poor sanitation where there is a lack of safe water and inadequate disposal of human excreta therefore sustain transmission of the STH. Other determinants include age (intensity of infection usually peaks in childhood), lack of education, poor living conditions, living in a wet, tropical climate and being involved in agricultural activities (Smith et al, 2001). These infections rarely cause death but their public health consequences are manifest in the chronic, insidious effects that the condition has such as malnutrition, anaemia, impeded growth and increased susceptibility to other infections (Montresor et al, 1998).…”

Section: Introductionmentioning

confidence: 99%

“…In both pre-school (1-4 years) and school-aged (5-14 years) children, the age-groups most at risk, STH infection stunts physical growth and impairs the development of cognitive function, hampering performance and attendance within the education system and ultimately hindering economic development (Montresor et al, 1998;Smith et al, 2001;Hotez et al, 2006). Social absenteeism, decreased worker-productivity, low self esteem and social exclusion are among the longer-term consequences (WHO, 2006).…”

Section: Introductionmentioning

confidence: 99%

Soil-transmitted helminthiasis in Latin America and the Caribbean: modelling the determinants, prevalence, population at risk and costs of control at sub-national level

Colston

Saboya

2013

Geospat Health

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Abstract. We present an example of a tool for quantifying the burden, the population in need of intervention and resources need to contribute for the control of soil-transmitted helminth (STH) infection at multiple administrative levels for the region of Latin America and the Caribbean (LAC). The tool relies on published STH prevalence data along with data on the distribution of several STH transmission determinants for 12,273 sub-national administrative units in 22 LAC countries taken from national censuses. Data on these determinants was aggregated into a single risk index based on a conceptual framework and the statistical significance of the association between this index and the STH prevalence indicators was tested using simple linear regression. The coefficient and constant from the output of this regression was then put into a regression formula that was applied to the risk index values for all of the administrative units in order to model the estimated prevalence of each STH species. We then combine these estimates with population data, treatment thresholds and unit cost data to calculate total control costs. The model predicts an annual cost for the procurement of preventive chemotherapy of around US$ 1.7 million and a total cost of US$ 47 million for implementing a comprehensive STH control programme targeting an estimated 78.7 million school-aged children according to the WHO guidelines throughout the entirety of the countries included in the study. Considerable savings to this cost could potentially be made by embedding STH control interventions within existing health programmes and systems. A study of this scope is prone to many limitations which restrict the interpretation of the results and the uses to which its findings may be put. We discuss several of these limitations.

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“…2 The high prevalence rate is attributed to lack of education, lack of latrines, occurrence of diarrhea, lower socio-economic status, inadequate disposal of human excreta and the level of sanitation in households. 3 In Nepal, the prevalence ranges from 27.0% to 76.4% in different studies carried out among general population in different geographical areas [4][5][6][7] ; whereas, hospital records in Nepal showed the infection rate of 30.0-40.0%. 4 Additionally, a hospital based study conducted by Rai et al (1995) over one decade in Kathmandu illustrated that intestinal parasitosis rate ranged from 29.1-44.2%, with a static prevalence of A. lumbricoides, the most common parasite in Nepal.…”

Section: Introductionmentioning

confidence: 99%

Intestinal Parasitosis

Shakya

Bhargava

Shrestha

et al. 2010

Journal of Institute of Medicine

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Prevalence and intensity of infections of Ascaris lumbricoides and Trichuris trichiura and associated socio-demographic variables in four rural Honduran communities

Cited by 61 publications

References 34 publications

Treatment of intestinal helminthiasis: mebendazole only or mebendazole-pyrantel pamoate?

Treatment of intestinal helminthiasis: mebendazole only or mebendazole-pyrantel pamoate?

Soil-transmitted helminthiasis in Latin America and the Caribbean: modelling the determinants, prevalence, population at risk and costs of control at sub-national level

Intestinal Parasitosis

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