Prevalence and mortality of congenital heart disease in Korean adults

Jang, Shin Yi; Seo, Su Ra; Moon, Ju Ryoung; Cho, Eun Jeong; Kim, EunKyoung; Chang, Sung-A; Song, Jieqiong; Huh, June; Kang, I-Seok; Kim, Duk Kyung; Park, Seung Woo

doi:10.1097/md.0000000000011348

Cited by 15 publications

(14 citation statements)

References 18 publications

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“…1 ). 15 The overall 10-year SR for ACHD was higher in non-AF patients (87.5%) than in AF patients (69.7%) ( P < 0.001) ( Fig. 2A ).…”

Section: Resultsmentioning

confidence: 91%

“…The prevalence and mortality were increased with aging in a Korean CHD study. 15 AF was more common in aging patients with CHD 20 21 and the incidence rate of AF in ACHD was higher for older age groups in Taiwan. 22 In our study, the mean age of the AF group was higher than that of the non-AF, and the proportion of AF became greater with aging in ACHD ( Table 2 ).…”

Section: Discussionmentioning

confidence: 91%

“…The data consisted of the diagnoses of CHD according to the ICD-10. 15 The diagnoses used were Q20, congenital malformations of cardiac chambers and connections; Q21, congenital malformations of cardiac septa; Q22, congenital malformations of pulmonary and tricuspid valves; Q23, congenital malformations of aortic and mitral valves; Q24, other congenital malformations of heart; Q25, congenital malformations of great arteries; and Q26, congenital malformations of great veins; and I27.8, Eisenmenger syndrome. The followings are the specific diagnoses of ACHD.…”

Section: Methodsmentioning

confidence: 99%

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Impact of Atrial Fibrillation on Survival in Adults with Congenital Heart Disease: a Retrospective Population-based Study

et al. 2021

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Background The number of adults with congenital heart disease (ACHD) with atrial fibrillation (AF) is expected to increase. We sought to assess the impact of AF on survival in Korean ACHD. Methods Records of AF in ACHD were extracted from the records of the Korea National Health Insurance Service from 2006 through 2015. Multiple Cox proportional hazards analyses were carried out after adjustment for age, sex, income level, AF, and comorbidities. Survival rates (SRs) with and without AF were compared. The death records from 2006 through 2016 were included. Results A total of 3,999 ACHD had AF (51.4% were male) and 62,691 ACHD did not have AF (43.5% were male); the proportion of ACHD who were 60 years and older was 53.0% and 27.0% in those with and without AF, respectively ( P < 0.001). The age-standardized incidence rate for AF was 1,842.0 persons per 100,000 people in the Korean general population from 2006 through 2015. For AF in ACHD, it was 5,996.4 persons per 100,000 ACHD during the same period, which was higher than that in the general population ( P < 0.001). Significantly higher proportion of death (20.9%) occurred in ACHD with AF than without AF (8.3%) ( P < 0.001). The adjusted hazard ratio for AF of death in ACHD was 1.39 (95% confidence interval, 1.29–1.50). The ten-year SR of ACHD with AF was 69.7% whereas it was 87.5% in non-AF ( P < 0.001). Conclusion In ACHD, AF occurs more frequently and has a worse prognosis than seen in the non-valvular general population in Korea. AF is associated with increased death in ACHD, especially with aging.

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“…1 ). 15 The overall 10-year SR for ACHD was higher in non-AF patients (87.5%) than in AF patients (69.7%) ( P < 0.001) ( Fig. 2A ).…”

Section: Resultsmentioning

confidence: 91%

Section: Discussionmentioning

confidence: 91%

Section: Methodsmentioning

confidence: 99%

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Impact of Atrial Fibrillation on Survival in Adults with Congenital Heart Disease: a Retrospective Population-based Study

et al. 2021

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“…In a previous investigation [9] it was reported that this trend derived from improvements in care, increasingly sensitive diagnostic tools, and increasing awareness of the potential relationships between common diseases and CHD. In our country, surgical mortality for CHD was relatively pretty low nowadays and the quality of imaging techniques is relatively so high [11].…”

Section: Discussionmentioning

confidence: 92%

Changes of hospitalization trend in the pediatric cardiology division of a single center by increasing adult with congenital heart disease

Lee

Kim

Kwon

et al. 2020

BMC Cardiovasc Disord

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Background: As a result of advances in pediatric care and diagnostic testing, there is a growing population of adults with congenital heart disease (ACHD). The purpose of this study was to better define the epidemiology and changes in the trend of hospitalizations for ACHD in Korean society. Methods: We reviewed outpatient and inpatient data from 2005 to 2017 to identify patient ≥18 years of age admitted for acute care with a congenital heart disease (CHD) diagnosis in the pediatric cardiology division. We tried to analyze changes of hospitalization trend for ACHD.

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“…Over the past two decades, the survival rate of patients with congenital heart disease (CHD) has markedly increased as a result of earlier diagnosis and advances in surgical and percutaneous interventions (Warnes, ). In the United States, up to approximately 90% of children with CHD are expected to survive into adulthood (Gurvitz et al, ), while the 10‐year survival rate for Korean adults with CHD has been reported to be as high as 92% (Jang et al, ). Despite these impressive developments, including increased survival rates and overall health status, psychosocial variables have been inadequately studied in the CHD population.…”

Section: Introductionmentioning

confidence: 99%

Mediating effects of exercise capacity on the association between physical activity and health‐related quality of life among adolescents with complex congenital heart disease

Kim

Jae

Choo

et al. 2019

American J Hum Biol

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Objectives: There is little evidence on interrelationships between physical activity, sedentary behaviors, and health-related quality of life (HRQOL) among adolescents with congenital heart disease (CHD). We hypothesized that exercise capacity would have a mediating effect on the associations of either physical activity or sedentary behavior with HRQOL. Methods: Adolescents with complex CHD (n = 111) were consecutively recruited from an outpatient clinic in a general hospital in South Korea. Physical activity and sedentary behavior were assessed using the global physical activity questionnaire.Exercise capacity was directly measured by peak oxygen uptake using a symptomlimited maximal treadmill exercise test. HRQOL was evaluated by both adolescents and their parents using the Pediatric Quality of Life Inventory questionnaire. Results: The self-reported and parent proxy-reported HRQOL were positively associated with physical activity (ß = 0.16, P = .003; ß = 0.12, P = .049) and exercise capacity (ß = 0.63, P < .001; ß = 0.66, P < .001), but not with sedentary behavior in adjusted regression models. When both variables were entered in the same regression models, only exercise capacity remained significantly associated with the self-reported (ß = 0.50, P = .008) and parent proxy-reported HRQOL (ß = 0.62, P = .003). Exercise capacity acted as a full mediator variable on the relationship between physical activity and HRQOL (P < .05 for both). Conclusions: The present findings suggest that exercise capacity mediates the association between physical activity and HRQOL, highlighting the importance of improving exercise capacity to potentially enhance HRQOL in adolescents with complex CHD.

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Prevalence and mortality of congenital heart disease in Korean adults

Abstract: Supplemental Digital Content is available in the text

Cited by 15 publications

References 18 publications

Impact of Atrial Fibrillation on Survival in Adults with Congenital Heart Disease: a Retrospective Population-based Study

Impact of Atrial Fibrillation on Survival in Adults with Congenital Heart Disease: a Retrospective Population-based Study

Changes of hospitalization trend in the pediatric cardiology division of a single center by increasing adult with congenital heart disease

Mediating effects of exercise capacity on the association between physical activity and health‐related quality of life among adolescents with complex congenital heart disease

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