Prevalence and non-invasive predictors of left main or three-vessel coronary disease: evidence from a collaborative international meta-analysis including 22 740 patients

D’Ascenzo, Fabrizio; Presutti, Davide Giacomo; Picardi, Elisa; Moretti, Claudio; Omedè, Pierluigi; Sciuto, Filippo; Novara, Marco; Yan, Andrew T.; Goodman, Shaun; Mahajan, Nitin; Kosuge, Masami; Palazzuoli, Alberto; Jong, Gwo Ping; Isma’eel, Hussain; Budoff, Matthew J.; Rubinshtein, Ronen; Gewirtz, Henry; Reed, Matthew J; Théroux, Pierre; Biondi‐Zoccai, Giuseppe; Modena, Maria Grazia; Sheiban, Imad; Gaïta, Fiorenzo

doi:10.1136/heartjnl-2011-301596

Cited by 79 publications

(49 citation statements)

References 60 publications

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“…Similarly other studies mentioned that Coronary artery disease (CAD) affects male more frequently and severely than female. [8][9][10] Regarding the risk factors, it was observed in this series that smoker was 68. About the complications, hypotension 6.7%, cardiogenic shock 6.7% and arrhythmias 6.7% in group I but not found in group II.…”

Section: Methodsmentioning

confidence: 95%

Prediction of Left Main Coronary Artery Occlusion by ST Segment Elevation in Lead aVR Greater than that in Lead V1 in Acute Coronary Syndrome

et al. 2017

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Background: The electrocardiogram (ECG) predicting an acute obstruction of the LMCA, which requires immediate aggressive treatment, is very important for early diagnosis. We correlated ST segment elevation in lead aVR greater than that in lead V with coronary angiographic diagnosis of LMCA occlusion in patients with acute coronary syndrome.Methods: Cross sectional analytical study was conducted in the Department of Cardiology, National Institute of Cardiovascular Diseases (NICVD), Dhaka, Bangladesh from August 2011 to July 2012. Total 90 patients were included purposively. Study population was divided into two groups. Group I- Patients with ST segment elevation in aVR greater than ST segment elevation in V (n=45) and group II- Patients with ST segment elevation in aVR less than that in lead V (n=45). In hospital outcomes were observed for cardiogenic shock, left ventricular failure, hypotension, arrhythmia and death.Results: Acute LVF was significantly (P<0.05) higher in group I but other complications were not significant (P>0.05) between two groups. LM involvement was significantly higher in group I (91.1% vs. 20.0%, p<0.05). ST segment elevation in aVR greater than ST segment elevation in V (n=45) for prediction of LM significant disease has got a sensitivity of 82.0%, specificity 90.0%, accuracy 85.6%, positive and negative predictive values were 91.1% and 80.0% respectively.Conclusion: ST segment deviation in lead aVR greater than that in lead V1 is supposed to be a positive predictor of left main coronary artery obstruction with highly sensitivity and accuracy. Precordial leads V1 and V6 can also predict the critical LMCA obstruction in patients with acute coronary syndrome.Cardiovasc. j. 2017; 9(2): 77-82

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Section: Methodsmentioning

confidence: 95%

Prediction of Left Main Coronary Artery Occlusion by ST Segment Elevation in Lead aVR Greater than that in Lead V1 in Acute Coronary Syndrome

et al. 2017

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“…В том числе, однососудистое поражение встретилось у 19,9%, двухсосудистое поражение -у 8,8%, трехсосудистое поражение и стеноз ствола ЛКА -по 1,4% больных [7]. Следует отметить, что в недавно опубликованном мета-анализе, включав-шем 22740 больных, поражение ствола ЛКА и/или трехсосудистое поражение КА выявлено при прове-дении КАГ у больных с острым коронарным синдро-мом в 20% случаев, а у больных с хронической ИБС -в 36% случаев [8].…”

Section: Discussionunclassified

“…Хотя рутинное использо-вание КАГ показало свое преимущество в ряде прове-денных исследований [6,7,9,10], по-видимому, будут продолжены попытки разработать оптимальную батарею неинвазивных тестов, способных выявить больных с наиболее вероятным поражением коро-нарных артерий [13]. Это может быть оценка степени дилатации сердца при стресс-ЭхоКГ [8], оценка каль-циевого индекса, таких биомаркеров, как мозговой натрий-уретический пептид [14], С-реактинвый белок [15], проведение МСКТ-ангиографии коро-нарных артерий. При этом необходимо будет учиты-вать не только медицинские показания, но и эконо-мическую эффективность.…”

Section: Discussionunclassified

Potential of coronary angiography in the assessment of cardiac complication risk during non-cardiac interventions

Sumin¹,

Безденежных²,

Evdokimov³

et al. 2013

Russ J Cardiol

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“…Left main disease (LMD) and three-vessel disease (3VD) have important prognostic value in patients with coronary artery disease. 7 We collected data of 200 consecutive patients with CAD during 2013 at our hospital (a tertiary care center) out of which 100 patients were having either TVD or LMD disease were included in our study. Inclusion criteria was coronary angiography showing LMD/TVD.…”

Section: Methodsmentioning

confidence: 99%

Non-Invasive Predictors and Prevalence of Left Main or Triple Vessel Disease in Patient With Coronary Artery Diseases

Baligar¹,

Hiregoudar²,

S.S³

et al. 2018

jebmh

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BACKGROUND Aim-Coronary artery disease is one of the common cause of death all over the world. There have been only few studies done regarding non-invasive predictors and prevalence of left main (LMD) or triple vessel disease (TVD) in patients with CAD. Uncertainties still exist about their prevalence and predictors in patients with CAD. Our aim was to detect non-invasive predictors, prevalence and clinical profiles of LMD/TVD patients.

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Prevalence and non-invasive predictors of left main or three-vessel coronary disease: evidence from a collaborative international meta-analysis including 22 740 patients

Abstract: This meta-analysis demonstrated that severe coronary disease-that is, LMD or 3VD-is more common in patients with ACS or stable coronary disease than generally perceived, and that simple and low-cost tools may help in the selection of the most appropriate therapeutic approach.

Cited by 79 publications

References 60 publications

Prediction of Left Main Coronary Artery Occlusion by ST Segment Elevation in Lead aVR Greater than that in Lead V1 in Acute Coronary Syndrome

Prediction of Left Main Coronary Artery Occlusion by ST Segment Elevation in Lead aVR Greater than that in Lead V1 in Acute Coronary Syndrome

Potential of coronary angiography in the assessment of cardiac complication risk during non-cardiac interventions

Non-Invasive Predictors and Prevalence of Left Main or Triple Vessel Disease in Patient With Coronary Artery Diseases

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