Prevalence and pattern of diabetic dyslipidemia in Indian type 2 diabetic patients

Parikh, Rakesh M.; Joshi, Shashank; Menon, P. S. N.; Shah, Nalini

doi:10.1016/j.dsx.2009.04.005

Cited by 41 publications

(25 citation statements)

References 6 publications

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“…Among study subjects with dyslipidemia 44.2% had mixed dyslipidemia , 32.6% had isolated single parameter dyslipidemia and 23.2% had combined two parameter dyslipidemia. Similar findings were observed by Cook et al, 14 Rakesh et al 15 and Pandya H et al 11 Abnormal lipid profile observed in type 2 DM was related to insulin resistance which leads to increased release of free fatty acids from fatty tissue and impaired insulin dependent muscle uptake of free fatty acids. 16 Chronic hyperglycemia causes glycation of apolipoproteins and interferes with the normal pathways of lipoprotein metabolism.…”

Section: Discussionsupporting

confidence: 79%

Study of prevalence and pattern of dyslipidaemia in type 2 diabetes mellitus patients attending rural health training centre of medical college in Bhopal, Madhya Pradesh, India

Borle

Chhari

Gupta

et al. 2016

Int J Community Med Public Health

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INTRODUCTIONDiabetes mellitus (DM) has become major public health problem in India. It is a metabolic disorder caused by impaired insulin secretion, peripheral insulin resistance or both. It is characterised by raised blood glucose with diminished uptake and metabolism of cellular glucose as well as altered lipid and protein metabolism.1 Diabetes is not only increasing morbidity and mortality but also decreases the quality of life. Also disease and its complications are causing heavy economic burden for patients suffering from it. 2,3ABSTRACT Background: Diabetes is endemic globally with increasing prevalence in both developing and developed countries. Persistent hyperglycaemia of diabetes is associated with micro as well as macro vascular complications like coronary heart disease, stroke, diabetic renal disease, diabetic retinopathy and neuropathy etc. Dyslipidemia contribute to considerable increased risk of atherosclerosis and consequent mortality in diabetic patients. It often precedes onset of diabetes particularly type 2 DM and may persist inspite of adequate control of blood sugar. The objective of the study was to study prevalence and pattern of dyslipidemia in type 2 diabetes mellitus patients attending Rural Health and Training Centre of medical college in Bhopal, Madhya Pradesh. Methods: This was a cross sectional study carried out among 50 Type 2 diabetic mellitus patients attending OPD of Rural Health Training Centre (RHTC) of medical college in Bhopal Madhya Pradesh. Study population included known as well as newly diagnosed type 2 diabetic patients more than 30 years of age attending OPD at RHTC. Results: According to ATP III guidelines dyslipidemia was observed in 43 (86%) study subjects. Hypercholesterolemia was seen in 18 (36%) study subjects. Increased LDL and triglycerides was observed in 33 (66%) and 32 (64%) study subjects respectively. Lower HDL cholesterol values were observed in 26 (52%) study subjects. Out of 43 study subjects having dyslipidemia, 14 (32.6%) study subjects were having isolated single parameter dyslipidemia, while 10 (23.2%) had combined two parameter dyslipidemia and 19 (44.2%) study subjects showed mixed dyslipidemia. Conclusion: Results suggest high (86%) prevalence of dyslipidemia among type 2 diabetes mellitus study subjects. Most common pattern observed was mixed type dyslipidemia. These lipid abnormalities might be the important in view of development of cardiovascular or cerebrovascular diseases. Hence type 2 diabetic patient should undergo the routine monitoring of blood sugar and lipid profile so that any abnormalities can be identified and preventive measures along with interventions can be initiated at the earliest.

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Section: Discussionsupporting

confidence: 79%

Study of prevalence and pattern of dyslipidaemia in type 2 diabetes mellitus patients attending rural health training centre of medical college in Bhopal, Madhya Pradesh, India

Borle

Chhari

Gupta

et al. 2016

Int J Community Med Public Health

View full text Add to dashboard Cite

show abstract

“…Dyslipidemia was most common risk factor observed among study population with prevalence of 86% in diabetes patients, which is much higher than reported 64.1% by Yadav et al in a cross sectional study at Gwalior, however it is lower than reported 91.2% by Parikh et al in a hospital based observational study at Jaipur. 9,10 Prevalence of hypertension among diabetic patients was 71% which was higher than reported 49% by Yadav et al 9 Proportion of all five CVD risk factors were observed to be higher among diabetic patients compared to non-diabetic patients in this study. Moreover, differences for dyslipidemia, hypertension and smoking were statistically significant (p<0.05).…”

Section: Discussioncontrasting

confidence: 58%

Cardio vascular risk profile among diabetic patients attending a tertiary care hospital in Odisha, India

et al. 2019

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Background: Diabetes is associated with reduced quality of life and wide range of complications including CVD which vary geographically. The likely causes for the dramatic increase in the CVD rates include lifestyle changes associated with urbanization and the epidemiologic as well as nutritional transitions that are associated with economic development. This study aims to identify the CVD risk factors that exists among the diabetes patients of Odisha.Methods: The study was conducted in KIMS during July-December 2016. A total of 300 diabetic and 300 non-diabetic patients were included in the study. Medical history and lifestyle data were collected using a pretested structured format and a separate checklist for laboratory results. Patient interview, physical examination and laboratory analysis were performed. Chi-square test was performed to identify significance of difference between prevalence of risk factors between diabetic and non-diabetic groups. Multiple logistic regression analyses (forward stepwise addition) were performed to identify the variables significantly associated with CVD risk factors. Significance level of 5% was considered.Results: Total 376 males and 224 females were enrolled in the study with higher proportion of male participants in both diabetic and non-diabetic groups. Overall mean age of study subjects was 47.5±10.4 years. No significant difference was observed for demographic distribution between both groups. Prevalence of dyslipidaemia among diabetic patients was 86%, while prevalence of hypertension and dyslipidaemia were 71% and 62.3% respectively.Conclusions: Overall prevalence of CVD risk factors observed in this study among population of Odisha, is higher compared to reported prevalence for other regions of India.

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“…Rakesh et al have also reported high LDL and low HDL in their study. 14 In this study, most of the patients had mixed dyslipidaemia with more than one lipid abnormality. The mixed dyslipidaemia observed most commonly in our study was high LDL levels and hypertriglyceridemia (38.2%) which is different from the western studies.…”

Section: Discussionmentioning

confidence: 99%

Pattern of dyslipidemia in Type 2 Diabetes Mellitus in Punjab

Bali

Vij

2016

Int J Res Med Sci

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Prevalence and pattern of diabetic dyslipidemia in Indian type 2 diabetic patients

Cited by 41 publications

References 6 publications

Study of prevalence and pattern of dyslipidaemia in type 2 diabetes mellitus patients attending rural health training centre of medical college in Bhopal, Madhya Pradesh, India

Study of prevalence and pattern of dyslipidaemia in type 2 diabetes mellitus patients attending rural health training centre of medical college in Bhopal, Madhya Pradesh, India

Cardio vascular risk profile among diabetic patients attending a tertiary care hospital in Odisha, India

Pattern of dyslipidemia in Type 2 Diabetes Mellitus in Punjab

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