Prevalence and risk factors of pregabalin misuse among patients with substance use disorder

Gabr, Amgad Ahmed Moshref

doi:10.4103/azmj.azmj_126_19

Cited by 6 publications

(5 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Moreover: the current study indicated that the highest percentages of the study and control groups were living in rural areas. This result finding congruent with (Gabr, 2014) [15] , who noted that the majority of women with breast cancer came from rural areas. In contrast to this (Wrońska, 2013) [42] , who documented that the highest percentage of the included sample were from urban areas and explained by the fact that the women in urban area are prone to use plastic and electrical appliances, cosmetics, high-fat diet, and processed meat, low fruits, vitamins, and vegetables.…”

Section: Discussionsupporting

confidence: 91%

Effect of early rehabilitation on shoulder pain and disability after modified radical mastectomy

Sayed¹,

Hashem²,

Mohammed³

et al. 2021

Int. J. Adv. Res. Nurs.

View full text Add to dashboard Cite

Background: Modified radical mastectomy (MRM) is a common surgical procedure used for breast cancer management. MRM often has a negative impact on shoulder function So, early rehabilitation play a critical role in managing shoulder dysfunction. Aim of the study: Determine the effect of early rehabilitation on pain and disability of the shoulder after modified radical mastectomy. Patients and method: A quasi-experimental research design was utilized in this study. It was conducted in the general surgery wards, oncology and general surgery out patient clinics at

show abstract

Section: Discussionsupporting

confidence: 91%

Effect of early rehabilitation on shoulder pain and disability after modified radical mastectomy

Sayed¹,

Hashem²,

Mohammed³

et al. 2021

Int. J. Adv. Res. Nurs.

View full text Add to dashboard Cite

show abstract

“…In line with our results, numerous studies found that pregabalin was frequently combined with other drugs but mostly opiates [21,22]. In contrast to our result Gabr found that heroin was not commonly abused with pregabalin 6.5% [5], and these differences may be due to different targeted population.…”

Section: Discussionsupporting

confidence: 85%

“…Pregabalin misuse is more prevalent among young people than in older age. Egyptian community needs more attention from family, educational, and health institutes for prevention and treatment of pregabalin abuse [5]. Recently in Egypt, ministry of health put pregabalin as schedule III of the controlled substance act.…”

Section: Introductionmentioning

confidence: 99%

Suicidal ideation and behavior among subjects with substance abuse disorder related to pregabalin

Ibrahim

Bayomy

Hussein

et al. 2022

Middle East Curr Psychiatry

View full text Add to dashboard Cite

Background Although pregabalin abuse is increasing worldwide and may be associated with increased suicidal ideation and behavior, few studies were done in Egypt searching for the effect of pregabalin on suicide. Eighty-three patients meeting DSM-IV criteria for substance abuse disorders related to pregabalin were identified from the addiction clinic of EL Khanka Psychiatric Hospital in Egypt for this observational cross–sectional study. We intended to assess suicidal ideation and behavior in patients with substance abuse disorder related to pregabalin and to identify the effects of other comorbid substances of abuse. All participants were subjected to semi-structured interview designed to collect and identify the socio-demographic data and patterns of substances 'use ,The Structured Clinical Interview for DSM-IV Axis I Disorders to diagnose patients with substance abuse disorder “related to pregabalin,” Beck Scale for Suicidal Ideation for assessment of suicidal ideation and behavior and urine screening test for pregabalin and other substances of abuse. Results Most of participants used pregabalin continuously {86.7%}. More than seventy nine percent of the patients abused both pregabalin and other substances, tramadol 67.4%, heroin 66.3%, cannabis 65.1%, other drugs 44.6%, and benzodiazepines 27.7%. Screening urine test was positive in 62.7% of participants most frequently was heroin 41% and cannabis 34.9%. No suicidal ideation was found in 67.4%, 19.3% had low risk of suicide, and 13.3% had high risk of suicide so total participants who had suicidal ideation were 32.6%. There was statistical significant increase in risk of suicide among patients who were continuously abusing pregabalin and who had positive pregabalin urine test. There was significant positive correlation between Beck Suicidal Ideation score and duration of abusing pregabalin, maximum and daily dose of pregabalin. Also, there was a statistical significant relation between suicidal ideation and associated tramadol abuse and this was positively correlated with dose and duration of tramadol abuse. Conclusions About one third of patients abusing pregabalin had a risk of suicide and this risk increased with associated tramadol abuse so pregabalin abuse is dangerous like other substances of abuse and must be used with caution under strict medical supervision

show abstract

“…In countries in the region, a cross-sectional study of 370 was conducted in the Kingdom of Saudi Arabia found that gabapentin and pregabalin abuse prevalence was 4.6% and 23.6% among a population aged 16-30 years old, respectively [27]. Another cross-sectional study from Egypt found that the prevalence of pregabalin abuse was 30.0% among a population of 400 substance use disorder and psychiatric disorders patients [28]. In our study, the prevalence of gabapentoids abuse was 3.9% among university students in Jordan, which happens to be slightly higher than global rates and those in the USA and the UK but was somewhat lower than regional rates in Egypt and Saudi Arabia.…”

Section: Discussionmentioning

confidence: 99%

Pregabalin and gabapentin abuse among university students in Jordan: A cross sectional study

Altarifi,

Obeidat,

Guzu

et al. 2024

ELECTRON J GEN MED

View full text Add to dashboard Cite

Introduction: Pregabalin and gabapentin (or gabapentanoids) have been reported to be abused for potentially euphoric effects. Objectives: In this work, we conducted a descriptive, cross-sectional study among university students from Jordan utilizing a structured online questionnaire. Results: 96.1% of the participants indicated no previous or current use of gabapentanoids, while 53 (3.9%) self-reported previous or current use (ever-use) of any of both drugs. The rate of abuse was higher among males and older students’ groups. 50.9% of drug users did not obtain a valid prescription. Most abusers indicated that their use of both drugs was for non-medical reasons (39.6%), and 69.8% students used both drugs despite being aware of their adverse effects. Hypersomnia was the most reported adverse effect. However, most participants (64.2%) did not report any withdrawal symptoms upon drug discontinuation. Marijuana/hashish was the most consumed substance with gabapentanoids. Conclusions: Our results invite for further prescribed drug control and increasing the awareness against drug abuse among the youth in Jordan.

show abstract

Prevalence and risk factors of pregabalin misuse among patients with substance use disorder

Cited by 6 publications

References 1 publication

Effect of early rehabilitation on shoulder pain and disability after modified radical mastectomy

Effect of early rehabilitation on shoulder pain and disability after modified radical mastectomy

Suicidal ideation and behavior among subjects with substance abuse disorder related to pregabalin

Pregabalin and gabapentin abuse among university students in Jordan: A cross sectional study

Contact Info

Product

Resources

About