Prevalence and Sensitivity of Bacterial Urinary Tract Infection among Adult Diabetic Patients in Misan Province, Iraq

Abstract

Urinary tract infections and their complications causing serious health problems especially in diabetic patients in Misan province, it is essential to determine the causative agent for appropriate treatment of this disease. One hundred and fifty urine samples were taken from adult patients with diabetes. The microbial growth appeared in 106 (70.6%) samples. Axenic culture was 83% versus 17% mixed growth. UTI prevalence was 65% with females comparing 35% of males and it was 56.6% in age group 35-49 years. Furthermore, UTIs were more incident in patients without antibiotics use and diabetic period 5-10 years (82% and 64%) respectively. Escherichia coli was identified as the most common causative agent of UTIs (52.9%), followed by Klebsiella pneumoniae and Enterococcus faecalis (9,1% and 6.6%, respectively). Streptococcus agalactiae and Klebsiella aerugenes were (4.2%, for each). Moreover, Pseudomonas aeruginosa, Klebsiella oxytoca and Staphylococcus haemolyticus were 2.48% for each. Additionally, the frequency of Proteus mirablis, Staphylococcus aureus, Streptococcus pyogenes, Serratia marcessens, Staphylococcus epidermidis and Staphylococcus warnerii was 1.65% for each, while Acinetobacter baumani and Bacillus subtilis were 0.82% for each. Most bacterial isolates had a high sensitivity to imipenem (78.8%) followed by amikacin (61.9%), but low sensitivity to ceftriaxone, tetracycline and Co-trimaxazole (36.4%, 29.7% and 26.3%, respectively) whereas, highly resistance to ampiclox and nitrofurantoin (98.3% and 87.3%, respectively). High rate of multidrug resistance observed among bacterial isolates.

Bacteriuria with Unusual Uropathogens in Diabetics in Thi-Qar Province

“…Female gender was mere susceptible to UTI in all investigated groups. The results are compatible with a previous study by Al-Tulaibawi (2019) in Misan province, Iraq, which showed that diabetic females are more susceptible to UTI. Seemingly the same results were concluded by (Alhamdany, 2018) at Babylon province .Also the same results were reported by (Taher et al, 2021) at Al-Kut province.…”

“…The leading isolated uropathogen was E. coli which in line with previous study by Al-Tulaibawi (2019) in Misan province , which showed the supremacy of E.coli over the other causative agents in regards to urine samples. Furthermore, agrees with the same terms as Tektook and Al-Lehibi, (2017)at the specialized center For endocrinology and diabetes of Baghdad city, Iraq.…”

Antibiogram Pattern of Uropathogenic Escherichia Coli in Baghdad Province, Iraq

“…The results of the present study corresponded to the result reported in Duhok Iraq [10] confirming that the majority (80.6%), of the microorganisms were Gram-negative. Furthermore, the results also corresponded with [11,12] who have ensured that UTI are common infections caused by bacteriuria. Previous studies in Iraq [13] and [14] also found that E. coli is the most common pathogen, which is associated with both community-and hospital-acquired UTI in many countries.…”

Update of the list of QPS‐recommended biological agents intentionally added to food or feed as notified to EFSA 12: suitability of taxonomic units notified to EFSA until March 2020

“…For one reference, no full paper was retrieved, and two papers did not deal with safety concerns. Three papers had serious methodological problems in relation to strain identification and source attribution and were not food related (Al-Tulaibawi, 2019;Nad aș et al, 2019;. Al-Tulaibawi (2019) described the isolation of B. subtilis from a urinary tract infection of diabetic patients; Thanganadar The ELS did not come up with any information that would change the status of the Bacillus species included in the QPS list and confirmed the qualification 'absence of cytotoxicity'.…”