Prévalence et transmission du Virus de l’Immunodéficience Humaine de la mère à l’enfant à N’Djamena

Hota, Mathieu; Yandai, Fissou Henry; Moussa, Ali Mahamat; Moustapha, Abbas; Mbanga, Djimadoum; Otchom, Brahim Boy

doi:10.4314/ijbcs.v13i4.24

Cited by 3 publications

(2 citation statements)

References 17 publications

(15 reference statements)

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“…This result is lower than that of Fatoumata [26] who found 17.65% at the Gabriel Touré University Hospital in Mali. In contrast, Hota and collaborators [27] found in their study an HIV/AIDS prevalence of 14.8% among children born to mothers living with HIV in N'Djamena, Chad (Figure 4).…”

Section: Resultsmentioning

confidence: 73%

Obstacles to the Integrated Care of Children Aged 6 to 59 Months Suffering from Acute and Severe Malnutrition at the Chu-Me and HATC of N&#8217;Djamena/Chad

Romain,

Soudy

2024

OJN

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Introduction: the problem of Severe Acute Malnutrition (SAM) and its consequences concern and challenge all social actors worldwide. The objective of the study was to identify the real obstacles that actors face in the integrated management of children aged 6 -59 months suffering from SAM at the University Hospital of Mother and Child (CHUME) and the Chad-China Friendship Hospital (HATC) of N'Djamena. Methodology: this is a crosssectional descriptive and interpretative study conducted from January to October 2023 at the CHUME and HATC of N'Djamena. It is based on questionnaires and direct observation of two hundred and thirty-six (236) parents or guardians of malnourished children admitted to these health facilities. All 236 agreed to participate freely in this study. Results: it appears from this study that the obstacles to the integrated management of malnourished children were: poor care-care relationship (26.7%) permanent product breaks (22.9%), the direct costs of services ranged from 30,000 to 60,000 FCFA (41.53%), drugs used for the treatment of patients came from the street (66.10%), malaria and anemia occupy an important place (27.5%), 57.2% respondents had monthly income below 60,000 CFAF. Conclusion: the present study carried out has identified the real bottlenecks to the integrated management of children suffering from SAM in the therapeutic nutritional units of the city of N'Djamena.

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Section: Resultsmentioning

confidence: 73%

Obstacles to the Integrated Care of Children Aged 6 to 59 Months Suffering from Acute and Severe Malnutrition at the Chu-Me and HATC of N&#8217;Djamena/Chad

Romain,

Soudy

2024

OJN

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“…The present prevalence is significantly lower compared to the 2016 and 2019 sentinel surveys with 5.75% and 4.26% respectively among pregnant women (12,13), including the results of studies which reported HIV prevalences of 5.70% (95% CI: 4.93-6.40), 6% (3.0-10.2%) and 7.8% respectively among pregnant women in Cameroon (18–20). Furthermore, the respective prevalence rates of 9.2% and 7.22% reported in the countries of Chad and Nigeria are also of relevance (21,22). Our findings therefore reflect the declining trend of HIV among pregnant women in Cameroon (7.6% in 2009 to 2.9% in 2016 (19,23) and from 3.4% in 2018 to 2.1% in 2022 (24–26).…”

Section: Discussionmentioning

confidence: 99%

Determinants of HIV infection among pregnant women in Cameroon: A contribution toward the elimination of vertical transmission in low- and middle-income countries

Ndié,

Awono Noah,

Ateba Ndongo

et al. 2024

Preprint

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Background The risk of HIV transmission during antenatal care (ANC) in Cameroon remains a concern. According to recent studies, the prevalence of HIV in the country is around 4.5%, which increases the likelihood of vertical transmission. Objective To identify the determinants of HIV infection among pregnant women attending antenatal clinics (ANC) in Cameroon and to estimate HIV seroprevalence. Methods A cross-sectional study was conducted among ANC attendees aged ≥15 years from September 2022 to June 2023 in 324 health facilities in 08 regions of Cameroon (Adamaoua, Yaounde, East, Far-North, Douala, North, West, South). Sociodemographic and clinical data were collected using questionnaire. HIV screening was performed according to the national algorithm. Estimates of HIV seroprevalence and identification of its determinants using multivariable logistic regression (95% CI) were performed with Excel and SPSS 22 software. Results Overall, 10674 pregnant women were enrolled, with median [IQR] age 25 years [21– 30]; 40.0% at a secondary educational level; 44.1% married monogamously; 46.3% multiparous; 38.8% in the second quarter of pregnancy and 16.5% reporting at least one abortion. Overall HIV seroprevalence was 2.6% [95%CI: 2.33; 2.93]. Significantly higher prevalence was found with the regions of Adamaoua (aOR 3.78 [95%CI: 1.87-7.67], p<0.001), East (9.38 [5.6-15.67], p<0.001), North (3.07 [1.74-5.42], p<0.001), South (2.93 [1.66-5.16]; p<0.001); lack of education (2.08 [1.06-4.06], p=0.032), primary education (2.44 [1.32-4.50], p=0.004) and secondary education (2.29 [1.28-4.08], p=0.005) were significantly associated with HIV infection, while monogamous marriage (0.33 [0.22-0.51], p<0.001), the absence of abortion (0.59 [0.37-0.98], p=0.036) and large multiparous (0.38 [0.17-0.82]; p=0.015) were protective. Conclusion Despite the overall low-prevalence among pregnant women at national-level, several factors are associated with HIV in ANC, the absence or low-level of education, being elderly (>30 years), singleness, history of abortion and low parity predicted the HIV status during ANC. Thus, public health interventions towards these at-risk target groups will help to reduce new infections among pregnant women, hence contributing to achieve eMTCT in Cameroon.

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Residual transmission of HIV infection from mother to child in the Atlantic and littoral departments in Benin

Dagba Gbessin,

Sina,

Keke

et al. 2024

BMC Pediatr

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Background The implementation of the WHO’s 2015 recommendations in Benin, requires an assessment of the progress made over time in preventing the transmission of the infection to exposed-infants, and the identification of its determinants. Methods This was a retrospective study of HIV-1 exposed-infants who underwent PCR between the 6th and 8th weeks of life. Early diagnostic tests were performed using the Abbott m2000 RealTime platform. Comparison of proportions tests (analysis of the significance of the difference in prevalence) with an error threshold of 5% were used to assess the determinants of the transmission. Statistical analysis was performed using R statistical software, version 4.1.3.0. Results A total of 5,312 infants benefited from early diagnosis by PCR between 2016 and 2021. Among them, 52% are males, tritherapy before pregnancy was the majority treatment used by mothers (30.6%) and monotherapy that of newborns (70%). Mixed breastfeeding is the feeding method with the highest prevalence. The overall transmission rate was 3.4% over the six years. The highest prevalence was achieved in 2018 (4.2%) and the lowest in 2021 (2.7%). The prevalence was lower when mothers were on tritherapy before pregnancy. The determinants of transmission were: mixed breastfeeding, lack of treatment in mothers (22.4%), lack of treatment in infants (19.7%), undefined treatments or absence of treatment in the mother-child pair. Conclusion This study shows the contribution over time of the PMTCT program to reducing HIV transmission among exposed-infants and also underlines the need for proper conduct of treatment in any women of childbearing age.

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Prévalence et transmission du Virus de l’Immunodéficience Humaine de la mère à l’enfant à N’Djamena

Cited by 3 publications

References 17 publications

Obstacles to the Integrated Care of Children Aged 6 to 59 Months Suffering from Acute and Severe Malnutrition at the Chu-Me and HATC of N&#8217;Djamena/Chad

Obstacles to the Integrated Care of Children Aged 6 to 59 Months Suffering from Acute and Severe Malnutrition at the Chu-Me and HATC of N&#8217;Djamena/Chad

Determinants of HIV infection among pregnant women in Cameroon: A contribution toward the elimination of vertical transmission in low- and middle-income countries

Residual transmission of HIV infection from mother to child in the Atlantic and littoral departments in Benin

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Prévalence et transmission du Virus de l’Immunodéficience Humaine de la mère à l’enfant à N’Djamena

Cited by 3 publications

References 17 publications

Obstacles to the Integrated Care of Children Aged 6 to 59 Months Suffering from Acute and Severe Malnutrition at the Chu-Me and HATC of N&amp;#8217;Djamena/Chad

Obstacles to the Integrated Care of Children Aged 6 to 59 Months Suffering from Acute and Severe Malnutrition at the Chu-Me and HATC of N&amp;#8217;Djamena/Chad

Determinants of HIV infection among pregnant women in Cameroon: A contribution toward the elimination of vertical transmission in low- and middle-income countries

Residual transmission of HIV infection from mother to child in the Atlantic and littoral departments in Benin

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Obstacles to the Integrated Care of Children Aged 6 to 59 Months Suffering from Acute and Severe Malnutrition at the Chu-Me and HATC of N’Djamena/Chad

Obstacles to the Integrated Care of Children Aged 6 to 59 Months Suffering from Acute and Severe Malnutrition at the Chu-Me and HATC of N’Djamena/Chad