Prevalence of Abdominal Obesity in China: Results from a Cross‐Sectional Study of Nearly Half a Million Participants

Zhang, Linfeng; Wang, Zengwu; Wang, Xin; Chen, Zuo; Shao, Lan; Tian, Ye; Dong, Ying; Zheng, Congyi; Li, Suning; Zhu, Manlu; Gao, Runlin

doi:10.1002/oby.22620

Cited by 64 publications

(53 citation statements)

References 29 publications

(30 reference statements)

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“…Interestingly, when conducting a subgroup analysis in BMI and WC, beneficial and more significant effects were found in the subgroup of females, Asia region studies, and duration of intervention ≥6 months (all p < 0.026). Reasonable explanations for the increased effect of vitamin D treatment in special groups may be the fact that obesity prevalence among women and Asians is higher than that in men and other areas [50, 51]. In particular, Asians are more likely to have central fat deposition despite having a lower BMI [52, 53].…”

Section: Discussionmentioning

confidence: 99%

Effects of Vitamin D Supplementation on General and Central Obesity: Results from 20 Randomized Controlled Trials Involving Apparently Healthy Populations

et al. 2020

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Background: The obesity pandemic has been paralleled by a high prevalence of vitamin D deficiency (VDD). There is growing epidemiological evidence linking low vitamin D status with obesity events. In addition, observational studies also show that obesity may increase the risk of VDD. However, there is insufficient knowledge to understand whether there is a causality between the two. Moreover, the impact of vitamin D supplementation on obesity indices has shown inconsistent outcomes. Objective: This meta-analysis aimed to assess whether vitamin D supplementation modified general and central obesity indices in apparently healthy populations. Methods: A systematic retrieval of relevant randomized controlled trials (RCTs) was undertaken using Pubmed, Embase, Web of Knowledge and Chinese National Knowledge Infrastructure databases. The pooled weighted mean difference (WMD) and 95% confidence intervals (CI) were used to assess the changes in body mass index (BMI), waist circumference (WC), waist-to-hip ratio (WHR) and 25-hy-droxyvitamin D (25[OH]D) from baseline. Results: Twenty RCTs involving 3,153 participants reporting either BMI, WC, WHR or 25(OH)D met the inclusion criteria. When compared with placebo, vitamin D supplementation had no significant decreases in BMI (WMD =-0.09 kg/m 2 , 95% CI-0.19 to 0.01, p = 0.08), WC (WMD =-0.71 cm, 95% CI-1.58 to 0.16, p = 0.112) or WHR (WMD = 0.00, 95% CI-0.01 to 0.01, p = 0.749). However, in the subgroups of females, Asia region studies and intervention duration ≥6 months, a beneficial and significant reduction in BMI and WC was noted (all p < 0.026). On the other hand, pooled results showed that there was a significant increase in serum 25(OH)D levels (WMD = 13.20 ng/mL, 95% CI 9.83-16.58, p < 0.001) after vitamin D intervention. No publication bias was found in our study. Conclusions: Overall, supplementation with vitamin D produced no significant effect on the BMI, WC or WHR of healthy adults.

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Section: Discussionmentioning

confidence: 99%

Effects of Vitamin D Supplementation on General and Central Obesity: Results from 20 Randomized Controlled Trials Involving Apparently Healthy Populations

et al. 2020

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“…The prevalence rates of CVD and cardiometabolic disorders have been reported to be high in this region. 42 , 43 , 44 This study followed the Strengthening the Reporting of Observational Studies in Epidemiology ( STROBE ) reporting guideline for cross-sectional studies. The Human Studies Committee of Sun Yat-sen University approved the study protocols.…”

Section: Methodsmentioning

confidence: 99%

Association Between Residential Greenness, Cardiometabolic Disorders, and Cardiovascular Disease Among Adults in China

Yang

Jalaludin

et al. 2020

JAMA Netw Open

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Key Points Question Is the general vegetation level of a residential area, referred to as residential greenness, associated with cardiovascular disease among adults, and does the presence of cardiometabolic disorders mediate or modify the association between residential greenness and cardiovascular disease? Findings In this cross-sectional study of 24 845 adults in China, residential areas with higher greenness levels were associated with a lower likelihood of cardiovascular disease. The presence of cardiometabolic disorders partially mediated the association between residential greenness and cardiovascular disease. Meaning The study’s findings may be helpful for health care professionals and policy makers in the development of strategies, such as planning for green spaces in residential areas, to mitigate the burden of cardiovascular disease.

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“…Unlike in Caucasian individuals, body fat in Chinese individuals tends to accumulate in the abdominal cavity, which is more likely to result in abdominal obesity. A study based on the Chinese population showed that abdominal obesity is currently an increasing trend in China, with an adult prevalence rate of 29.1% (28.6% for men and 29.6% for women) [55]. More importantly, the prevalence rates of T2DM in the overweight and obese population in China are 12.8% and 18.5%, respectively [56].…”

Section: Effect Of Vfa On Cimt In Patients With T2dmmentioning

confidence: 99%

Analysis of risk factors for carotid intima-media thickness in patients with type 2 diabetes mellitus in Western China assessed by logistic regression combined with a decision tree model

Zhou

Qiu

Yang

et al. 2020

Diabetol Metab Syndr

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Background: Cardiovascular disease (CVD) is the leading cause of morbidity and mortality in patients with type 2 diabetes (T2DM). Carotid intima-media thickness (CIMT) is considered a preclinical stage of atherosclerosis. Therefore, it is necessary to identify the related risk factors for CIMT to facilitate the early prevention of CVD. Previous studies have shown that visceral fat area (VFA) is a risk factor for T2DM and CVD. However, few studies have focused on the effects of VFA on CIMT associated with T2DM. Moreover, considering that the body fat distribution shows regional and racial heterogeneity, the purpose of this study was to investigate the predictive value of VFA and other risk factors for CIMT associated with T2DM in Western China. Methods: In a cross-sectional study, a total of 1372 patients with T2DM were divided into the CIMT (−) group (n = 965) and the CIMT (+) group (n = 407) based on CIMT values. In addition to the univariate analyses, logistic regression analysis and a decision tree model were simultaneously performed to establish a correlation factor model for CIMT. Results: Univariate analyses showed that sex, smoking status, age, heart rate, systolic blood pressure (SBP), diastolic blood pressure (DBP), height, weight, body mass index (BMI), waist circumference, hip circumference, waist-hip ratio, VFA, subcutaneous fat area, and the levels of 2-h C-peptide, serum creatinine, urea nitrogen and uric acid were significantly different between the two groups (all p < 0.05). Smoking, increased VFA, female sex and increased BMI were risk factors in the logistic regression analyses (OR = 5.759, OR = 1.364, OR = 2.239, OR = 1.186, respectively). In the decision tree model, smoking was the root node, followed by sex, waist circumference, VFA and chronic kidney disease (CKD) in order of importance. Conclusions: In addition to smoking, sex and BMI, VFA has a significant effect on CIMT associated with T2DM in the Chinese Han population in Western China. In addition, the decision tree model could help clinicians make more effective decisions, with its simplicity and intuitiveness, making it worth promoting in future medical research.

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Prevalence of Abdominal Obesity in China: Results from a Cross‐Sectional Study of Nearly Half a Million Participants

Cited by 64 publications

References 29 publications

Effects of Vitamin D Supplementation on General and Central Obesity: Results from 20 Randomized Controlled Trials Involving Apparently Healthy Populations

Effects of Vitamin D Supplementation on General and Central Obesity: Results from 20 Randomized Controlled Trials Involving Apparently Healthy Populations

Association Between Residential Greenness, Cardiometabolic Disorders, and Cardiovascular Disease Among Adults in China

Analysis of risk factors for carotid intima-media thickness in patients with type 2 diabetes mellitus in Western China assessed by logistic regression combined with a decision tree model

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