Prevalence of Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis and Tannerella forsythia in Japanese patients with generalized chronic and aggressive periodontitis

Tomita, Sachiyo; Komiya-Ito, Akiyo; Imamura, Kentaro; Kita, Daichi; Ota, Keiko; Takayama, S; Makino-Oi, Asako; Kinumatsu, Takashi; Ota, Mikio; Saitô, Atsushi

doi:10.1016/j.micpath.2013.04.006

Cited by 66 publications

(76 citation statements)

References 34 publications

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“…Only a few reports of aggressive periodontitis cases exist in the literature affecting the primary dentition without evidence of an underlying systemic disease (Suzuki et al 2003;Portaro et al 2008). Some studies report that aggressive periodontitis is related to the existence of Aa (Tomita et al 2013). The analysis of the subgingival plaque in this case also revealed a massive infection with Aa.…”

Section: Discussionmentioning

confidence: 62%

Rare case of generalised aggressive periodontitis in the primary dentition

Spoerri

Signorelli

Erb

et al. 2014

Eur Arch Paediatr Dent

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Section: Discussionmentioning

confidence: 62%

Rare case of generalised aggressive periodontitis in the primary dentition

Spoerri

Signorelli

Erb

et al. 2014

Eur Arch Paediatr Dent

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“…The authors of various studies on P. gingivalis have reported that these pathogens are able to pollute soft tissues and flee the surgical debridement of periodontal lesions (28,29). Many epidemiological studies report a positive association between the presence of P. gingivalis and periodontal diseases (7,25,(30)(31)(32)(33)(34)(35)(36), whereas in some studies, no association was found between the presence of P. gingivalis and periodontal diseases (20,(37)(38)(39)(40)(41). This has also been shown by Kumar et al (42).…”

Section: Discussionmentioning

confidence: 99%

“…Periodontal diseases can be described as one of the predominant polymicrobial infections of humans, which can advance and lead to gum retrogression, soft tissue harm, weakness of the bone, eventual osteoporosis and tooth loss (severe periodontitis). Periodontal disease have many risk factors including smoking and diabetes, moreover, several bacteria have been connected to the intensity and progress of periodontitis (2,3).…”

Section: Introductionmentioning

confidence: 99%

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Study of Porphyromonas gingivalis in periodontal diseases: A systematic review and meta-analysis

Rafiei

Kiani

Sayehmiri

et al. 2017

Med. J. Islam. Republic Iran

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Background: The mouth cavity hosts various types of anaerobic bacteria including Porphyromonas gingivalis, which causes periodontal inflammatory diseases. P. gingivalis is a gram-negative oral anaerobe and is considered as a main etiological factor in periodontal diseases. Several studies have reported a relationship between P. gingivalis in individuals with periodontal diseases and a critical role of this bacterium in the pathogenesis of periodontal diseases. The present study aimed at estimating this probability using a meta-analysis.Methods: We searched several databases including PubMed, Scopus, Google Scholar, and Web of Science to identify case-control studies addressing the relationship between P. gingivalis with periodontal diseases. A total of 49 reports published from different countries from 1993 to 2014 were included in this study. I² (heterogeneity index) statistics were calculated to examine heterogeneity. Data were analyzed using STATA Version 11.Results: After a detailed analysis of the selected articles, 49 case-control studies with 5924 individuals fulfilled the inclusion criteria for the meta-analysis. The healthy controls included 2600 healthy individuals with a Mean±SD age of 36.56±7.45 years. The periodontal diseases group included 3356 patients with a mean age of 43.62±8.35 years. There was a statistically significant difference between P. gingivalis in periodontal patients and healthy controls; 9.24 (95% CI: 5.78 to 14.77; P = 0.000). In the other word, there was a significant relationship between the presence of P. gingivalis and periodontal diseases.Conclusion: Analyzing the results of the present study, we found a strong association between the presence of P. gingivalis and periodontal diseases. This result suggests that another research is needed to further assess this subject.

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“…Standard curves were then constructed based on a crossing point determined by the fit point method. The proportions of the three pathogens within the total bacterial count were estimated as described previously (10,35).…”

Section: Sample Collectionmentioning

confidence: 99%

Characterization of specimens obtained by different sampling methods for evaluation of periodontal bacteria

Okada

Sogabe

Takeuchi

et al. 2017

Journal of Oral Science

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Quantitative analysis of periodontal bacteria is considered useful for clinical diagnosis, evaluation and assessment of the risk of periodontal disease. The purpose of this study was to compare the effectiveness of sampling of saliva, supragingival and subgingival plaque for evaluation of periodontal bacteria. From each of 12 subjects, i) subgingival plaque was collected from the deepest pocket using a sterile paper point, ii) stimulated whole saliva was collected after chewing gum, and iii) supragingival plaque was collected using a tooth brush. These samples were sent to the medical examination laboratory for quantitative analysis of the counts of three periodontal bacterial species: Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia. The proportions of these bacteria in subgingival plaque were higher than those in saliva or supragingival plaque, but lower in subgingival plaque than in saliva or supragingival plaque. In several cases, periodontal bacteria were below the levels of detection in subgingival plaque. We concluded that samples taken from subgingival plaque may be more useful for evaluating the proportion of periodontal bacteria in deep pockets than is the case for other samples. Therefore, for evaluation of periodontal bacteria, clinicians should consider the characteristics of the specimens obtained using different sampling methods.

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Prevalence of Aggregatibacter actinomycetemcomitans, Porphyromonas gingivalis and Tannerella forsythia in Japanese patients with generalized chronic and aggressive periodontitis

Cited by 66 publications

References 34 publications

Rare case of generalised aggressive periodontitis in the primary dentition

Rare case of generalised aggressive periodontitis in the primary dentition

Study of Porphyromonas gingivalis in periodontal diseases: A systematic review and meta-analysis

Characterization of specimens obtained by different sampling methods for evaluation of periodontal bacteria

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