Prevalence of anaemia among HIV-infected patients in Benin City, Nigeria

Abstract

Abstract:The aim of this study was to use the World Health Organization (WHO) definition of anaemia to determine prevalence of anaemia among human immunodeficiency virus (HIV)-infected patients on the highly active antiretroviral therapy (HAART) and those that are HAART naive. Haemoglobin concentration was measured in 457 HIV patients consisting of 217 patients on HAART (86 males and 131 females) and 240 HAART naive patients (106 males and 134 females). According to WHO criteria, anaemia was defined as a haemoglobin concentration below 12g/dl in women and below 13g/dl in men. The anaemic HIV patients were further categorized according to WHO/ACTG anaemia toxicity grades. An overall anaemia prevalence of 60.61% was observed. The prevalence of anaemia was significantly higher among HAART naive patients (69.17%) than in HIV patients on HAART (51.15%) (P < 0.001). The prevalence of anaemia differ significantly (P < 0.05) between males and females of HAART naive patients with males (76.42%) having higher prevalence than females (63.43%). The WHO/ACTG categorization showed the same pattern between HIV patients on HAART and those that were HAART naive. Conclusively, the overall prevalence of anaemia was 60.61% among HIV patients. HAART naive patients have higher prevalence as well as males in this group. The WHO definition of anaemia is recommended as this will give the true prevalence of anaemia and allow for policy and interventions to address it. _______________________________________________________________________________________

Evaluation of Hematological Parameters in HIV Reactive Patients on Antiretroviral Therapy and Treatment Naïve Patients: A Comparative Study

“…This probably indicates improvement in hemoglobin after ART. This observation was in concordance with study conducted by Omoregie et al Mathews et al and Thulasi et al, [15][16][17] the prevalence of anemia in their studies was as shown in above table.…”

“…Similarly, Tripathi et al reported mean hematocrit of 27.36% and it was found to be 31.31% in a study by Parinitha et al [9,13] Red cell distribution width: In the present study, Mean value of RDW-CV was found to be 15.67±2.59% in group A and 14.56±1.70% in Group B, which was in concordance to study conducted by Enawgaw et al and Parinitha et al in treatment naïve HIV reactive patients. [9,14] [15] 69.17% 51.15% Mathews et al [16] 45.3%…”

Risk of zidovudine-induced anemia on human immunodeficiency virus (HIV) infection patients with different CD 4 cell counts

“…15 Although gender, age, weight and clinical stage have reported as risk factor for anemia in HIV patients in previous studies, 1,3,4,16 in the present study did not find as risk factor. However, the level of Hb before based ART has been found as risk factor in this study.…”

Anaemia and Pro-inflammatory Cytokines in Human Immunodeficiency Virus Infection

“…The results showed that the prevalence of anaemia in the combined group was 40.7%. However, higher prevalence rates of 60.61% and 64.0% were observed in Benin City, South-south, Nigeria [23] and in Keffi Northcentral, Nigeria [24] respectively. A lower prevalence rate of 23% has been recently reported from Ghana [7].…”