Prevalence of Anemia and Its Association with Frailty, Physical Function and Cognition in Community-Dwelling Older Adults: Findings from the HOPE Study

Lee, Chun‐Tsu; Chen, Matthew; Yip, Christina; Yap, Eng Soo; Lee, S. Y.; Merchant, Reshma Aziz

doi:10.1007/s12603-021-1625-3

Cited by 31 publications

(16 citation statements)

References 49 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Other studies in north-eastern Thailand, Philippines, and India showed anemia prevalence of 48%, 21.6%, and 68.7%, respectively in the elderly [34][35][36]. However, Indonesia and all of these countries are in contrast with Singapore and Taiwan which had a lower anemia prevalence of 15.2% and 18.8%, respectively [37,38]. The difference in prevalence between countries may be caused by heterogeneity in living conditions, elderly healthcare, health problems, and socioeconomic factors.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of Anemia and Factors Associated With Handgrip Strength in Indonesian Elderly Population

Sutandyo¹,

Rinaldi²,

Sari³

et al. 2022

Cureus

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Prevalence of Anemia and Factors Associated With Handgrip Strength in Indonesian Elderly Population

Sutandyo¹,

Rinaldi²,

Sari³

et al. 2022

Cureus

View full text Add to dashboard Cite

“…[31][32][33] However, Indonesia and all of these countries are in contrast with Singapore and Taiwan that had a lower anemia prevalence 15.2% and 18.8% respectively. 34,35 The difference in prevalence between countries may be caused by heterogeneity in living conditions, elderly healthcare, health problems, and socioeconomic factors.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of Anemia and Its Association with Handgrip Strength in Indonesian Elderly Population: A Cross-Sectional Study Using Indonesian Family Life Survey Data Year 2014-2015

Sutandyo¹,

Rinaldi²,

Sari³

et al. 2021

Preprint

View full text Add to dashboard Cite

Aim This study aimed to elucidate the prevalence of anemia in Indonesian elderly population aged ≥60 years old and to analyze its association with handgrip strength in the elderly. Method This was a cross-sectional study using data from Indonesian Family Life Survey-5 (IFLS-5). All participants aged ≥60 years old were included in this study. Exclusion criteria were: (1) respondents who refused to take health measurements (hemoglobin level, handgrip strength, weight, stature, and waist circumference); (2) respondents with incomplete or missing data; (3) respondents with history of stroke; and (4) respondents with history of pain, swelling, inflammation, injury, and surgery on one or both hands within the last 6 months. The dependent variable for this study was handgrip strength. The independent variables were hemoglobin level, gender, age, body mass index (BMI), waist circumference, smoking history, comorbidities, and current use of drug therapies. Statistical analyses included correlation, bivariable, and multivariable analyses. Result A total of 3192 individuals were selected for analysis. Overall, 38.8% of participants aged ≥60 years had anemia based on definition of anemia by WHO. There was a positive correlation between hemoglobin level and handgrip strength in Indonesian elderly population (r: 0.349; p value: 0.000). Multivariable analysis showed that anemia was significantly associated with weak handgrip strength (OR: 1.557; 95% CI: 1.314-1.846; p value: 0.000). This association was stronger for males and elderly aged ≥80 years old. Conclusion Based on the results, anemia was associated with weak handgrip strength in Indonesian elderly population and it is more pronounced in males and elderly aged ≥80 years old.

show abstract

“…In the Chinese population aged over 60 and above, the age-adjusted prevalence of anemia varies from 8.5 to 35.4% (13). In Asian people, anemia is negatively associated with handgrip strength, muscle mass, and physical performance (14)(15)(16), all of which are components in sarcopenia diagnosis.…”

Section: Introductionmentioning

confidence: 99%

Hemoglobin level is negatively associated with sarcopenia and its components in Chinese aged 60 and above

Liu

You²,

Zhong³

et al. 2023

Front. Public Health

View full text Add to dashboard Cite

IntroductionSarcopenia and low hemoglobin level are common in older adults. Few studies have evaluated the association between hemoglobin level and sarcopenia and with inconsistent findings. The multifaceted effects of sarcopenia on the human body and the high prevalence of anemia in the Chinese population make it necessary to explore the association between the two.MethodsUsing the China Health and Retirement Longitudinal Study (CHARLS), we explored the association between hemoglobin with sarcopenia and its components in the Chinese population aged 60 and above. Multivariate logistic and Cox proportional hazards models were constructed to examine the association of hemoglobin level with sarcopenia and sarcopenia components in individuals aged 60 years or above. The subgroup analysis covered residence, body mass index level, drinking status, and smoking status were conducted. The possible difference of associations between sexes was also explored.ResultsWith a total of 3,055 people, the hemoglobin concentration in people without sarcopenia, possible sarcopenia, and sarcopenia are 14.34 ± 2.22, 14.64 ± 2.27, and 13.58 ± 2.02 g/dl, respectively. Cross-sectional analysis showed strong evidence that hemoglobin was negatively associated with sarcopenia [Odds Ratio (OR) = 0.95, 95% Confidence Interval (CI): 0.90–0.99] and low height-adjusted appendicular skeletal muscle mass (OR = 0.91, 95% CI: 0.86–0.97). On average, a per 1 g/dl higher hemoglobin level was associated with 5% lower odds of sarcopenia (OR = 0.95, 95% CI: 0.90–0.98). The cohort study of 1,022 people demonstrated a statistically significant negative association of hemoglobin level with low physical performance [Hazard Ratio (HR) = 0.92, 95% CI: 0.85–0.99], merely with sarcopenia (HR = 0.92, 95% CI: 0.84–1.00) and skeletal muscle mass (HR = 0.95, 95% CI: 0.80–1.00). Sex-specific analysis suggested hemoglobin's association with sarcopenia, muscle mass, and physical performance in all sexes, with weaker magnitudes in females. Hemoglobin in urban residents and people with high body mass index (BMI) has a larger magnitude of the negative association with sarcopenia.DiscussionHemoglobin level associates with sarcopenia, muscle mass, and physical performance in the Chinese population aged 60 and above, with sex-specific, residence-specific, and BMI-specific effects.

show abstract

Prevalence of Anemia and Its Association with Frailty, Physical Function and Cognition in Community-Dwelling Older Adults: Findings from the HOPE Study

Cited by 31 publications

References 49 publications

Prevalence of Anemia and Factors Associated With Handgrip Strength in Indonesian Elderly Population

Prevalence of Anemia and Factors Associated With Handgrip Strength in Indonesian Elderly Population

Prevalence of Anemia and Its Association with Handgrip Strength in Indonesian Elderly Population: A Cross-Sectional Study Using Indonesian Family Life Survey Data Year 2014-2015

Hemoglobin level is negatively associated with sarcopenia and its components in Chinese aged 60 and above

Contact Info

Product

Resources

About