Prevalence of anti-retroviral treatment failure and salvage therapy in university of Benin Teaching Hospital Edo state, Nigeria

First-line antiretroviral treatment failure and associated factors in HIV patients following highly active antiretroviral therapy at the Shashemene Referral Hospital, Oromia region, Ethiopia

“…This study showed that the prevalence of HIV first-line treatment failure was 14.5%. This result is similar to an outcome of study conducted at the Bugando Hospital Mwanza, Tanzania, in which immunologic failure rate was 17.1% [12] and much higher than study conducted at the University of Benin Teaching Hospital, Nigeria, where the failure rate was 1.19% [13] as well as study from the Gondar University Referral Hospital, Ethiopia [14]. This considerable difference is may be due to that the majority of patients in our study-initiated HAART after advancement of WHO stage, with 27.5% of patients presenting with stage 3 and 13% patients with stage 4.…”

“…This study showed that treatment failure rate was more frequent in males 70% (7 patients) than in females 30% (3 patients), and 31-44 years age group 80% (8 patients) were more affected than other age group. The study conducted at the Benin Teaching Hospital, Nigeria, also reported that most of first-line treatment failures occurred in 30-40 age group and was more frequent amongst males (1.3%) compared to females (1.1%) [13].…”