Prevalence of antibodies against hepatitis C virus in the adult German population

Palitzsch, Klaus‐Dieter; Hottenträger, Barbara; Schlottmann, Klaus; Frick, E; Holstege, Axel; Schölmerich, Jürgen; Jilg, Wolfgang

doi:10.1097/00042737-199911000-00005

Cited by 65 publications

(50 citation statements)

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“…The relatively low overall prevalence of anti-HCV antibodies (1.3%) among Libyans is still higher than Canada (0.8%), Australia (1.1%) and some western European countries including France (1.1%) and Germany (0.6%) [13][14][15][16][17] and is close to that reported from large studies of the general population in the United States of America (1.8%-2.2%) [18][19][20][21] and much lower than the figures reported for Pakistan (5%-7%) [22,23] and Egypt (22%) [24], a neighbouring country with a high movement of workers every year. The results of this study also are consistent with previously published studies of selected Libyan populations [6][7][8][9][10][11].…”

Section: Discussionmentioning

confidence: 99%

Prevalence of hepatitis B and C virus infections and their related risk factors in Libya: a national seroepidemiological survey

An¹,

Mn²,

Sammud³

et al. 2013

East Mediterr Health J

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A high prevalence of hepatitis B (HBV) and C virus (HCV) infections has been reported among specific patient groups in Libya; a survey was thus designed to determine the extent of the problem at the national level. A multistage sampling design covering all administrative areas of Libya was applied, covering > 65 000 individuals of all age groups. All subjects gave a blood sample and completed a questionnaire on demographic and risk behaviour data. The prevalence of HBV surface antigen (HBsAg) and anti-HCV were 2.2% and 1.3% respectively. The prevalence of anti-HCV increased with age, rising gradually after age 30 years, in contrast to a stable prevalence of HBsAg in all age groups 10+ years. Age-adjusted risk factors for HCV infection were previous hospitalization, surgical operations, previous blood transfusions and intravenous drug use; for HBV infection only family exposure or contact with HBV case were identified.1 Department of Medicine, Hamad General Hospital, HMC, Doha, Qatar (Correspondence to A.-N. Elzouki: nelzouki_1999@yahoo.com

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Section: Discussionmentioning

confidence: 99%

Prevalence of hepatitis B and C virus infections and their related risk factors in Libya: a national seroepidemiological survey

An¹,

Mn²,

Sammud³

et al. 2013

East Mediterr Health J

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“…Sex, age, body mass index (BMI) and personal data were compared with statistical data on the total German population provided by the German Federal Statistics Office (Statistisches Bundesamt, Wiesbaden, Germany). The cohort revealed no significant difference with regards to these parameters as compared with the total German population, and was therefore considered representative (14,15). All study subjects gave informed consent for the Diabetomobil study.…”

Section: Study Populationmentioning

confidence: 99%

Association between serum ferritin and the insulin resistance syndrome in a representative population

et al. 2006

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Objective: Unexplained hepatic iron overload with increased serum ferritin (SF) values has been associated with the insulin resistance syndrome (IRS), defined by the presence of one or more of the following criteria: increased body mass index (BMI), diabetes, hyperlipidemia or hypertension. However, as yet the association between IRS and SF in a representative population has not been investigated. Methods: The study subjects participated in a nationwide epidemiological survey on metabolic disorders in the adult German population. The 1200 probands included in this study are representative of the German population. To eliminate major causes of secondary iron overload, 114 (9.5%) subjects with excessive alcohol consumption and 16 (1.5%) subjects with serological evidence for hepatitis B or C were excluded. For all remaining 1070 probands, complete clinical data of SF, HbA1c, known diabetes, BMI, cholesterol, high-density lipoprotein-cholesterol and blood pressure were available. Results: SF values were significantly increased in men and women with high BMI (. 25 kg/m 2 ), increased cholesterol (. 200 mg/dl), and increased systolic (. 160 mmHg) blood pressure, in women with diabetes, and in men with increased diastolic (. 95 mmHg) blood pressure. Furthermore, there was a significant correlation between the number of IRS criteria and SF. Conclusions: This study shows a significant correlation between SF and the presence of IRS criteria in a large representative population. Interestingly, the severity of the IRS seems to be associated with increased SF levels suggesting a causal connection. Further studies are required to investigate the pathophysiological mechanism and consequences of increased SF levels in patients with IRS.European Journal of Endocrinology 154 333-340

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“…One of the strongest predictors of anti-HCV positivity is the duration of injection drug use. [19][20][21][22][23][24][25][26][27][28] In an ongoing cohort study of untreated illicit opiate users in five cities across Canada, saliva tests indicated 61% anti-HCV positivity. 29 Other evidence of the high rates of anti-HCV comes from specific Canadian cities.…”

Section: Injection Drug User Populationsmentioning

confidence: 99%

Injection Drug Use and the Hepatitis C Virus: Considerations for a Targeted Treatment Approach--The Case Study of Canada

Fischer

Haydon

Rehm

et al. 2004

Journal of Urban Health: Bulletin of the New York Academy of Me

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Prevalence of antibodies against hepatitis C virus in the adult German population

Cited by 65 publications

References 0 publications

Prevalence of hepatitis B and C virus infections and their related risk factors in Libya: a national seroepidemiological survey

Prevalence of hepatitis B and C virus infections and their related risk factors in Libya: a national seroepidemiological survey

Association between serum ferritin and the insulin resistance syndrome in a representative population

Injection Drug Use and the Hepatitis C Virus: Considerations for a Targeted Treatment Approach--The Case Study of Canada

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