Prevalence of antibodies against hepatitis e virus among urban and rural populations in Venezuela

Pujol, Flor H.; Favorov, Michael O.; T, Marcano; Esté, José A.; Magris, Magda; Liprandi, Ferdinando; Khudyakov, Yury; Khudyakova, N. S.; Fields, Howard A.

doi:10.1002/jmv.1890420305

Cited by 55 publications

(33 citation statements)

References 9 publications

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“…Meanwhile, residents in rural areas in Rio de Janeiro (Sumidouro) had a similar seroprevalence (2.1%; 95% CI, 0.5-6.4) 7 . Regarding studies conducted in rural populations in Latin America, similar anti-HEV IgG prevalence rates were also reported in Bolivia (6.3%; 95% CI, 3.6-10.3) 11 and Venezuela (5.4%; 95% CI, 2.9-9.4) 12 , but a higher rate was reported in Mexico (36.6%; 95% CI, 31.0-42.7) 13 . Differences in regional endemicity, risk characteristics, and the performance of diagnostic assays for hepatitis E are the possible reasons for these differences in the observed rates.…”

supporting

confidence: 63%

Hepatitis E seroprevalence and associated factors in rural settlers in Central Brazil

Freitas

Teles

Caetano

et al. 2017

Rev. Soc. Bras. Med. Trop.

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Introduction: Prevalence of hepatitis E virus (HEV) infection and associated factors were investigated in rural settlements in Central Brazil. Methods: A total of 464 settlers were interviewed, and serum samples were tested for anti-HEV IgG/IgM. Positive samples were tested for HEV RNA. Results: Sixteen participants (3.4%; 95% CI 2.0-5.7) were positive for anti-HEV IgG. None was positive for anti-HEV IgM. HEV RNA was not detected. Dwelling in a rural settlement for >5 years was associated with HEV seropositivity. Conclusions: The results revealed the absence of acute infection and a low prevalence of previous exposure to HEV.

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supporting

confidence: 63%

Hepatitis E seroprevalence and associated factors in rural settlers in Central Brazil

Freitas

Teles

Caetano

et al. 2017

Rev. Soc. Bras. Med. Trop.

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“…In Venezuela, Puyol et al (1994) reported seroprevalence rates ranging from 1.6 to 5.4% in three different populations (pregnant women of urban area, rural people and Amerindians).…”

Section: Seroprevalence In Humans and Pigsmentioning

confidence: 99%

Molecular Epidemiology of Hepatitis E Virus (Hev) in South America: Current Status

Mirazo¹,

Ramos²,

Arbiza³

2012

VR&R

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Hepatitis E virus (HEV) is a common causative agent of acute hepatitis in many developing countries where standards of sanitation and hygiene are poor. HEV is transmitted primarily by the fecal-oral route. However, zoonotic trasmission from animal reservoirs to human by consumption of raw or undercooked meat has also been suggested. In endemic areas, HEV infection occurs as large waterborne epidemics and/or small outbreaks. Sporadic cases of HEV infection have also been reported in developed countries, where its occurrence is not always associated with travel to highly endemic areas. HEV mammalian isolates are classifi ed into four genotypes 1-4, which appear to have a specifi c host range and geographical distribution. The epidemiology of HEV in South America seems to be complex and seroprevalence in human and domestic pigs diff ers both among populations within the same countries and between countries. Additionally, HEV strains have been detected and molecularly characterized and genotype 3 is the most frequently genotype found in the region. Moreover, except for two strains isolated from autochthonous cases of acute hepatitis that occurred in Venezuela and belonged to genotype 1, all sequences detected in South America were classifi ed as within genotype 3. Our understanding of HEV epidemiology has undergone major changes in recent years and despite the fact that several attempts to shed light over the epidemiology of this infection have been carried out in South America, data about the molecular characterization of HEV isolates is still lacking and further investigation is needed. This review summarizes the current status of HEV molecular epidemiology from a regional point of view.

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“…También se han hecho algunos estudios en población indígena en Bolivia, Venezuela y Chile, en los cuales se ha demostrado una seropositividad para HEV entre 5,4 y 20,1 % (27,32,34,35). En trabajos realizados en Chile y Perú en grupos de riesgo, como trabajadores de la salud, presidiarios y operarios del sistema de agua y alcantarillado, se detectaron anticuerpos anti-HEV en un rango de 7,5 a 12,5 % de las muestras (36).…”

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Infección por el virus de la hepatitis E en pacientes con diagnóstico clínico de hepatitis viral en Colombia

et al. 2014

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Prevalence of antibodies against hepatitis e virus among urban and rural populations in Venezuela

Cited by 55 publications

References 9 publications

Hepatitis E seroprevalence and associated factors in rural settlers in Central Brazil

Hepatitis E seroprevalence and associated factors in rural settlers in Central Brazil

Molecular Epidemiology of Hepatitis E Virus (Hev) in South America: Current Status

Infección por el virus de la hepatitis E en pacientes con diagnóstico clínico de hepatitis viral en Colombia

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