Prevalence of Antibodies to Epstein-Barr Virus, Cytomegalovirus and Toxoplasma in a Mexican Highland Community

Golubjatnikov, R; Allen, Virginia D.; Steadman, Marjorie; Blancarte, Pilar Olmos; Inhorn, Stanley L.

doi:10.1093/oxfordjournals.aje.a121488

Cited by 16 publications

(5 citation statements)

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“…Previous studies declared that there is no difference in EBV seroprevalence between different genders in children ( 24 - 26 ). In the present study, there was also no significance difference in EBV primary infection incidence between males and females.…”

Section: Discussionmentioning

confidence: 95%

The Incidence of Epstein-Barr Virus Primary Infection Among Suspected Patients Referred to Namazi Hospital of Shiraz, Iran

Moeini

Ziyaeyan

Asaei

et al. 2015

Jundishapur J Microbiol

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Background:Many children become infected with Epstein-Barr virus (EBV) during their childhood. Since the clinical profile of EBV primary infection is challenging, it is important to use the best diagnostic clinical means. Detection of IgM against viral capsid antigen (VCA) by ELISA has been shown to be a reliable method.Objectives:This study was conducted to demonstrate the incidence of EBV primary infection, among suspected patients referred to Namazi hospital, Shiraz, Iran.Patients and Methods:The sample included 346 patients with an age range of 0 to 20 years (6.31 ± 4.66: 10.97 years). A volume of 5 mL of blood was collected from each case. The patients were divided to four age groups. The sera were tested for the presence of VCA-IgM by commercially available Anti-EBV-VCA ELISA kit.Results:The results indicated that 104 (30.0%) of the patients were EBV VCA IgM positive, with no significant difference in the incidence of EBV primary infection between males and females. However, the incidence of infection was significantly different between age group I (0 - 5 years) and III (11 - 15 years), and also between age group I (0 - 5 years) and IV (16 - 20 years) (P < 0.05).Conclusions:Considering the results, accurate and on time diagnosis of EBV primary infection in both children and adolescents will help prevent unnecessary hospitalization, medication and incorrect medical decisions. In addition, this will decrease further treatment costs and related medical procedures.

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Section: Discussionmentioning

confidence: 95%

The Incidence of Epstein-Barr Virus Primary Infection Among Suspected Patients Referred to Namazi Hospital of Shiraz, Iran

Moeini

Ziyaeyan

Asaei

et al. 2015

Jundishapur J Microbiol

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“…In another series Porter et al (1969) observed that the prevalence was 80 % in children aged 2-4 years but this rose to 90 % by the age of 14. The frequency of EBV-positive sera in 3-year-old children was reported as 80% in a Japanese population by Hinuma et al (1969) and 888 % in a Huixquilucan population by Golubjatnikov et al (1973), who also found a frequency of 93-5 % in Mexican children and 39-4 % in American children (Wisconsin) aged between 5 and 9 years. In the present study, it was found that the frequency of EBV-positive sera was 38 % in West Australian children (Caucasian) aged 5-6 years ( Table 1).…”

Section: Discussionmentioning

confidence: 97%

Epidemiological studies of Epstein–Barr herpesvirus infection in Western Australia

Lai¹,

Mackay‐Scollay²,

Alpers

1975

J. Hyg.

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SUMMARYIn a study on a Caucasian population in Western Australia the prevalence of antibodies to Epstein-Barr virus (EBV) was 41 % in the 9-to 10-year age group, 80 % in the 16 to 19-year age group and 92 % in young adults. The age-specific annual seroconversion rates indicated two peaks of primary EBV infection in the population studied -one under 5 years of age and the other at adolescence. The geometric mean titre rose with age, from 23 at 5-6 years to 53 at 36-40 years.It was shown that in 73 families studied there was evidence of probable spread of EBV infection among siblings, particularly between those of the same sex.Serological study of patients with infectious mononucleosis indicated that 100 % of those examined had antibody to EBV and the geometric mean titre was elevated to 210. Rising titres and seroconversion was demonstrated in these patients together with successful establishment of EBV-carrying cell lines from the peripheral blood in two-thirds of the cases.

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“…These findings echoed earlier results from a seroepidemiologic study of H. pylori in Mexico, where higher household crowding [a common feature of Hispanic enclaves in the United States (60)], lower educational level, and lower SES were independently associated with higher risk of infection (61). Besides H. pylori infection, differences in the prevalence of tobacco smoking, which is more common in foreign-born than U.S.-born Hispanic men [but not women (49)], and infection with Epstein-Barr virus, which usually occurs earlier in foreign-born Hispanics and those living in lower SES, higher enclave neighborhoods (62, 63), may also partially account for some of the observed nativity patterns (17–19). …”

Section: Discussionmentioning

confidence: 99%

Gastric Cancer Incidence among Hispanics in California: Patterns by Time, Nativity, and Neighborhood Characteristics

Chang

Gomez

Fish

et al. 2012

Cancer Epidemiology, Biomarkers &Amp; Prevention

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Background Better understanding about gastric cancer incidence patterns among Hispanics by birthplace, socioeconomic status (SES), and acculturation can improve preventive strategies and disease models. Methods Incidence rates, rate ratios, and estimated annual percent change (EAPC) in rates of anatomic and histologic subtype-specific gastric cancer were calculated by age, sex, and nativity among Hispanics using California Cancer Registry data from 1988 through 2004. Incidence rates in 1998 to 2002 were compared by neighborhood SES and Hispanic enclave status according to 2000 US Census data. Results Incidence rates of diffuse gastric cancer increased from 1988 through 2004 among foreign-born Hispanic men (EAPC: 3.5%, 95% CI: 1.5%–5.5%) and U.S.-born Hispanic women (EAPC: 3.0%, 95% CI: 0.7%–5.3%). During the same time period, incidence rates of intestinal gastric cancer declined significantly and both cardia and noncardia gastric cancer were steady or declined among foreign-born and U.S.-born Hispanic men and women. Noncardia and both intestinal and diffuse gastric cancer were more common in foreign-born than U.S.-born Hispanic men and women, and in those from lower SES, higher enclave neighborhoods. By contrast, among younger and middle-aged Hispanic men, cardia tumors were more common in the U.S.-born than the foreign-born, and in higher SES, lower enclave neighborhoods. Conclusions Varying gastric cancer risk factors among Hispanic subgroups and increasing rates of diffuse gastric cancer in foreign-born Hispanic men and U.S.-born Hispanic women merit further investigation to identify separate disease etiologies. Impact Age, sex, birthplace, SES, and acculturation modify gastric cancer incidence in Hispanics and should be considered when examining disease risk and prevention.

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Prevalence of Antibodies to Epstein-Barr Virus, Cytomegalovirus and Toxoplasma in a Mexican Highland Community

Cited by 16 publications

References 0 publications

The Incidence of Epstein-Barr Virus Primary Infection Among Suspected Patients Referred to Namazi Hospital of Shiraz, Iran

The Incidence of Epstein-Barr Virus Primary Infection Among Suspected Patients Referred to Namazi Hospital of Shiraz, Iran

Epidemiological studies of Epstein–Barr herpesvirus infection in Western Australia

Gastric Cancer Incidence among Hispanics in California: Patterns by Time, Nativity, and Neighborhood Characteristics

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