Prevalence of Asymptomatic SARS-CoV-2 Infection in Children and Adults in Marion County, Indiana

Wood, James B.; Datta, Dibyadyuti; Hudson, Brenda; Co, Katrina; Tepner, Sarah; Hardwick, Emily; John, Chandy C.

doi:10.7759/cureus.9794

Cited by 6 publications

(11 citation statements)

References 10 publications

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“…Among 95 studies, 18 were excluded because that the percentage of asymptomatic infections among the confirmed population was 100%. 22 , 30 , 31 , 36 , 39 , 43 , 49 , 56 , 58 , 71 , 77 , 79 , 80 , 81 , 87 , 96 , 101 , 108 The remaining 77 studies were included in the meta-analysis for the percentage of asymptomatic infections among the confirmed population, 12 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 32 , 33 , 34 , 35 , 37 , 38 , 40 , 41 , 42 , 44 , 45 , 46 , 47 , 48 , 50 , 51 , 52 , 53 , 54 , 55 , 57 , 59 , 60 , 61 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 <...>…”

Section: Resultsmentioning

confidence: 99%

Global Percentage of Asymptomatic SARS-CoV-2 Infections Among the Tested Population and Individuals With Confirmed COVID-19 Diagnosis

et al. 2021

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Key Points Question What is the percentage of asymptomatic individuals with positive test results for SARS-CoV-2 among tested individuals and those with confirmed COVID-19 diagnosis? Findings In this systematic review and meta-analysis of 95 unique studies with 29 776 306 individuals undergoing testing, the pooled percentage of asymptomatic infections was 0.25% among the tested population and 40.50% among the population with confirmed COVID-19. Meaning The high percentage of asymptomatic infections from this study highlights the potential transmission risk of asymptomatic infections in communities.

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Section: Resultsmentioning

confidence: 99%

Global Percentage of Asymptomatic SARS-CoV-2 Infections Among the Tested Population and Individuals With Confirmed COVID-19 Diagnosis

et al. 2021

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“…Children with COVID-19 rarely present with severe respiratory symptoms and frequently remain asymptomatic [6], whereas adults more commonly develop respiratory symptoms of variable severity [7]. Children younger than 10 years with no identified SARS-CoV-2 exposure have been diagnosed with asymptomatic SARS-CoV-2 infection [8]. In contrast with adults, children with COVID-19 typically experience a mild illness with a good prognosis [9].…”

Section: Introductionmentioning

confidence: 99%

Assessment of SARS-CoV-2 Anti-Spike IgG Antibody in Women and Children in Madinah, Saudi Arabia: A Single-Center Study

Mahallawi

Ibrahim

Aljohani

et al. 2021

IJERPH

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Background: Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Information on the prevalence of SARS-CoV-2 antibodies in women and children in Madinah has been limited. The current study aimed to evaluate SARS-CoV-2 IgG seropositivity among women and children at Madinah Maternity and Children’s Hospital. Methods: In this cross-sectional study, 579 participants were recruited between January and April 2021 from Madinah Maternity and Children’s Hospital, Saudi Arabia. Data concerning age, sex (for children), blood group, and height and weight (for women) were collected from the hospital database. SARS-CoV-2 anti-spike (anti-S) IgG antibodies were detected by enzyme-linked immunosorbent assay (ELISA). Results: Over 58% of children (n = 195), including 60% of children ≤1 year (n = 75), and 50.2% (n = 124) of women were SARS-CoV-2 anti-S IgG seropositive. Significantly higher anti-S IgG levels were observed in children than in women (0.78 ± 1.05 vs. 0.65 ± 0.98, p = 0.008). Compared with women, children had higher odds of high SARS-CoV-2 anti-S IgG levels (odds ratio: 1.41; 95% confidence interval: 1.01–1.97; p = 0.041). No significant associations were observed for anti-S IgG levels with age in women or children or with body mass index among women. Conclusion: Non-reported COVID-19 infections were more prevalent among children than women, and non-reported COVID-19 infections children represent a viral transmission risk; therefore, increased screening, especially among school-aged children, may represent an important COVID-19 preventive control measure.

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“…In our community, the estimated asymptomatic carrier rate is 43%. 8 SARS-CoV-2 testing has a reported false-negative rate of 2% to 29%. 9 Nasopharyngeal swabbing may be distressing to patients who are developmentally unable to cooperate, and it may be challenging to obtain a sufficient sample.…”

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confidence: 99%

Aerosol Generation During Myringotomy With Tympanostomy Tube Insertion: Implications for Otolaryngology in the COVID‐19 Era

Campiti

Sharma

et al. 2021

Otolaryngol.--head neck surg.

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The risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission to health care workers during myringotomy and tympanostomy tube (MT) insertion is unknown. To determine the need for enhanced precautions to prevent potential spread via aerosolized particles, we used an optical particle sizer to measure aerosol generation intraoperatively during a case series of MT insertion. We also discuss our institutional experience with safe pandemic-era perioperative practices. There was no measured increase in aerosol particle number during the procedure at a distance of 30 cm from the external auditory canal. These initial data are reassuring regarding the risk of SARS-CoV-2 transmission to the operating room team due to aerosol generation, but further study is necessary before making definitive recommendations.

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Prevalence of Asymptomatic SARS-CoV-2 Infection in Children and Adults in Marion County, Indiana

Abstract: Wood et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0., which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Cited by 6 publications

References 10 publications

Global Percentage of Asymptomatic SARS-CoV-2 Infections Among the Tested Population and Individuals With Confirmed COVID-19 Diagnosis

Global Percentage of Asymptomatic SARS-CoV-2 Infections Among the Tested Population and Individuals With Confirmed COVID-19 Diagnosis

Assessment of SARS-CoV-2 Anti-Spike IgG Antibody in Women and Children in Madinah, Saudi Arabia: A Single-Center Study

Aerosol Generation During Myringotomy With Tympanostomy Tube Insertion: Implications for Otolaryngology in the COVID‐19 Era

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