Prevalence of Bronchial Asthma among Schoolchildren in a Swedish District

Bråbäck, Lennart; Kälvesten, L.; Sundström, Gunnar

doi:10.1111/j.1651-2227.1988.tb10762.x

Cited by 32 publications

(16 citation statements)

References 13 publications

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“…In contrast, less than 40% were exposed to cat allergen in their homes and only 17% were exposed to cockroach allergen. In areas where the allergen exposure pattern is different, other allergens are significantly and independently associated with disease (10,16,22,33). In Los Alamos, New Mexico, and Sweden, sensitization to allergens derived from domestic animals has been associated with asthma (10,33).…”

Section: Discussionmentioning

confidence: 97%

Sensitization to Dust Mites as a Dominant Risk Factor for Asthma among Adolescents Living in Central Virginia

Squillace

Sporik

Rakes

et al. 1997

Am J Respir Crit Care Med

170

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Factors influencing asthma were investigated in a population of school children in central Virginia. A survey of 1,054 children in two middle schools (one urban and one suburban) identified 135 students with symptoms suggestive of asthma. Eighty-eight symptomatic children and 123 control subjects were randomly selected for further evaluation by skin testing using common indoor and outdoor allergens; serum assays for total IgE and specific IgE; dust samples assayed for mite (Der p 1 Der f 1), cat (Fel d 1), and cockroach (Bla g 2) allergens; and provocation with histamine to test for bronchial hyperreactivity. Forty-eight of the children with symptoms responded to < or = 3.9 mumol of histamine and were considered to have asthma. Marginal analysis identified elevated total IgE and dust mite, cat, and cockroach sensitization as significant risk factors for asthma. Using multiple regression, only dust mite sensitization was independently associated with asthma (odds ratio = 6.6; p < 0.0001). Dust from 81% of the houses contained high levels of mite allergen (> 2 micrograms/g), while approximately 40% of the children were exposed to cat and 17% were exposed to cockroach allergen. In this population, there was no significant association between asthma and race, socioeconomic status, home smoking, sensitization to outdoor allergens, or allergen concentration in the child's home. In an area where there is a high prevalence of asthma and most houses contain high concentrations of dust mite allergen, sensitization to this allergen is the dominant risk factor for asthma defined as symptomatic bronchial hyperreactivity

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Section: Discussionmentioning

confidence: 97%

Sensitization to Dust Mites as a Dominant Risk Factor for Asthma among Adolescents Living in Central Virginia

Squillace

Sporik

Rakes

et al. 1997

Am J Respir Crit Care Med

170

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“…Some studies on asthma epidemiology have revealed what seems to be a geographic difference in the prevalence of asthma [2,12,13,18,[24][25][26][27]. In a review, COOKSON [11] concluded that there are true differences in cumulative prevalence of asthma-like illnesses between countries, and suggested that they could be explained by environmental variations.…”

Section: Comparison Between Centresmentioning

confidence: 99%

“…In a review, COOKSON [11] concluded that there are true differences in cumulative prevalence of asthma-like illnesses between countries, and suggested that they could be explained by environmental variations. In Sweden, a number of studies have focused on the prevalence of asthma [9,15,18,25,28], and in this country as well as some others it has been proposed that this prevalence might differ between regions [14,15,18]. ÅBERG [14] found the prevalence of asthma and allergic rhinitis to be highest among those born in the northernmost provinces of the country, and, in a recent study, LARSON et al [15] found differences both in reported respiratory symptoms and in the consumption of drugs for asthma, between two neighbouring counties.…”

Section: Comparison Between Centresmentioning

confidence: 99%

Symptoms related to asthma and chronic bronchitis in three areas of Sweden

Björnsson¹,

Plaschke²,

Norrman³

et al. 1994

Eur Respir J

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S Sy ym mp pt to om ms s r re el la at te ed d t to o a as st th hm ma a a an nd d c ch hr ro on ni ic c b br ro on nc ch hi it ti is s i in n tWheezing was reported by 20.5%, and the combination of wheezing without a cold and wheezing with breathlessness by 7.4%. The use of asthma medication was reported by 5.3%. Long-term cough and/or morning cough together with problems with phlegm was reported by 12.8%; the prevalence being highest in the most polluted area (Göteborg). When using multivariate analysis, no significant difference in asthma-related symptoms was found between the centres. Women reported cough more frequently, but otherwise gender did not influence symptom prevalence.Our results indicate that bronchitis symptoms occur more frequently in Göteborg, the most polluted of the Swedish centres, but that the prevalence rates of asthmarelated symptoms do not differ between these three regions.

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“…This is particularly the case for pollinosis, whereas pollen counts are usually higher in urban than in rural areas. Selection bias may act by selecting people who can live in the countryside (285,854,(962)(963)(964), but confounding factors are likely to exist.…”

Section: Variations In Allergy Prevalencementioning

confidence: 99%