ABSTRACT… Objective:To compare the levels of creatine kinase-MB in male and female patients of acute myocardial infarction before and after the treatment. Study design: Comparative study. Setting: Faisalabad Institute of Cardiology, Faisalabad, Pakistan. Period: 08 months, March 2014 to September 2014. Material & Methods: Total 60 patients of acute myocardial infarction were enrolled in the study; 30 males and 30 females. The creatine kinase-MB levels of all the patients were checked and compared before starting the treatment for acute myocardial infarction and then after 24 &48 hours of treatment. Results: The results of the study shown that the mean of CK-MB levels before treatment was high in male as compared to female patients with p-value < 0.01. Similarly the comparison of mean CK-MB levels after 24 and 48 hours of treatment were also found to be significantly higher in male patients with p-value <0.01 each. Conclusion: The levels of CK-MB in male acute myocardial infarct patients were high both before and after the treatment.
Key words:Myocardial infarction, Creatine kinase-MB, Cardiovascular diseases, Troponin, Electrocardiogram, Cardiac biomarkers