Prevalence of cardiovascular risk factors and management practices of acute coronary syndrome in a tertiary care hospital

Chandrasekhar, Dilip; Cholamugath, Shinu; Baby, Molniya; Pattani, Danisha

doi:10.1515/jbcpp-2014-0055

Cited by 9 publications

(8 citation statements)

References 14 publications

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“…We have observed that the median age of ACS was 54 years among smokers and 73 years among patients treated for hypertension. Our results were in agreement with those of Dilip et al [ 15 ]. Due to the increased rate of cardiac events in smokers, further efforts for smoking cessation must be performed.…”

Section: Discussionsupporting

confidence: 94%

“…Diabetes was associated with all ACS and to UA/NSTEMI. Our results are consistent with literature data [ 15 , 35 , 36 ]. Ahmadi et al concluded that patients with metabolic syndrome have a significantly greater prevalence, severity, and prognosis of coronary artery disease [ 37 ].…”

Section: Discussionsupporting

confidence: 94%

“…This relatively low Tunisian ACS prevalence can be explained by lifestyle differences and local habits [ 14 ]. The UA/NSTEMI predominance in our study was similar to that described by Dilip et al [ 15 ] and El-Menyar et al [ 16 ] and different than the results of Bacci [ 17 ]. Gender and age distribution correlated with ACS are widely described in the literature [ 18 , 19 ].…”

Section: Discussionsupporting

confidence: 67%

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Management of acute coronary syndrome in emergency departments: a cross sectional multicenter study (Tunisia)

et al. 2018

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BackgroundWe aimed to describe diagnosed acute coronary syndrome (ACS) and its care management and outcomes in emergency departments (EDs) and to determine related cardiovascular risk factors (CVRFs).MethodsWe conducted a cross sectional multicenter study that included 1173 adults admitted to EDs for acute chest pain (ACP) in 2015 at 14 sites in Tunisia. Data included patients’ baseline characteristics, diagnosis, treatment and output.ResultsACS represented 49.7% of non-traumatic chest pain [95% CI: 46.7–52.6]; 74.2% of ACS cases were unstable angina/non-ST-segment-elevation myocardial infarction (UA/NSTEMI). Males represented 67.4% of patients with ACS (p < 0.001). The median age was 60 years (IQR 52–70). Emergency medical service transportation was used in 11.9% of cases. The median duration between chest pain onset and ED arrival was two hours (Inter quartile ranges (IQR) 2–4 h). The age-standardized prevalence rate was 69.9/100,000 PY; the rate was 96.24 in men and 43.7 in women. In the multivariable analysis, CVRFs related to ST segment elevation myocardial infarction were age correlated to sex and active smoking. CVRFs related to UA/NSTEMI were age correlated to sex, familial and personal vascular history and type 2 diabetes. We reported 27 cases of major adverse cardiovascular events (20.0%) in patients with STEMI and 36 in patients with UA/NSTEMI (9.1%).ConclusionHalf of the patients consulting EDs with ACP had ACS. Emergency medical service transportation calls were rare. Management delays were acceptable. The risk of developing an UA/NSTEMI was equal to the number of CVRFs + 1. To improve patient outcomes, it is necessary to increase adherence to international management guidelines.

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Section: Discussionsupporting

confidence: 94%

Section: Discussionsupporting

confidence: 94%

Section: Discussionsupporting

confidence: 67%

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Management of acute coronary syndrome in emergency departments: a cross sectional multicenter study (Tunisia)

et al. 2018

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“…Although there is no a higher percentage of diabetics into the STEMI group with respect to NSTEMI, Mexican adults may be transitioning to this state, and therefore, in the coming years, this population will have more cases of STEMI with diabetics as it is seen in other developing countries such as India (the population with the highest burden of ACS), where there are reports of this trend [12,13].…”

Section: Discussionmentioning

confidence: 99%

Good Practices in the Clinical Management of Patients with Acute Coronary Syndrome: Retrospective Analysis in a Third-Level Hospital in Mexico

Flores-Salinas

Casillas-Muñoz

Valle

et al. 2020

Cardiology Research and Practice

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Introduction and Objective. In Mexico, there has been an increase in the risk of cardiovascular disease due to rising life expectancy, westernized lifestyle, lack of prevention, and industrialized exposure. This article describes the pharmacological treatment, surgical interventions, and associated clinical complications in patients diagnosed with acute coronary syndrome (ACS) and their impact on in-hospital mortality frequency in a Cardiology Unit in Instituto Mexicano del Seguro Social. Methods. This is a retrospective study including male and female patients aged ≥18 years who were diagnosed with ACS. The collected data included demographic characteristics, risk factors, medications, electrocardiograms, surgical procedures, and in-hospital deaths. Results. There are at least 20% more diagnoses of ST-segment elevation myocardial infarction in this hospital compared to the latest national reports in Mexico. The most common risk factors were type 2 diabetes mellitus, hypertension, smoking, and dyslipidaemia. Diabetic patients with a clinical history of percutaneous coronary intervention had a higher risk of non-ST-segment elevation myocardial infarction than nondiabetics (OR: 2.34; p=0.013), also smoking patients with previous heart surgery than nonsmokers (OR: 7.73; p=0.0007). The average in-hospital mortality was 3.6% for ACS. Conclusions. There is a higher percentage of coronary interventionism and improvement in pharmacological treatment, which is reflected in lower mortality. The substantial burden of T2DM could be related to a higher number of cases of STEMI. Diabetics with precedent percutaneous coronary intervention and smokers with previous heart surgery have an increased risk of subsequent infarction.

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“…Moreover, omentin-1 levels are inversely correlated with obesity, body mass index, hemoglobin, cholesterol, and type 2 diabetes mellitus [ 5 ]. Serum omentin-1 level was low in the most types of ischemic heart disease compared to normal subjects [ 6 ], but serum omentin-1 is positively correlated with high density lipoprotein (HDL) that is independently correlated with IHD, and many studies showed a significant correlation between low omentin-1 serum level and progressions of IHD [ 7 ].…”

Section: Introductionmentioning

confidence: 99%

New Insights into the Role of Metformin Effects on Serum Omentin-1 Levels in Acute Myocardial Infarction: Cross-Sectional Study

Al-Kuraishy

Al-Gareeb

2015

Emergency Medicine International

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Background. Serum omentin-1 level was low in the most types of ischemic heart disease compared to normal subjects; it also dependently correlated with coronary heart disease; thus, omentin-1 is regarded as a novel biomarker in IHD. Objective. The aim of the present study was to establish the links between omentin-1 and acute myocardial infarction in metformin patients. Subjects and Methods. A cross-sectional study was performed on eighty-five patients with type II DM and acute MI. They are divided as follows: Group I, 62 patients with type II DM who received metformin prior to onset of acute MI; Group II, 23 patients with type II DM who did not receive metformin prior to onset of acute MI; and Group III, 30 normal healthy controls. Venous blood was drawn from each participant for determination of lipid profile, plasma omentin-1, cardiac troponin-I (cTn-I) and other routine tests. Results. Patients that presented with acute MI that received metformin show a significant difference in all biochemical parameters (p < 0.001); metformin increases serum omentin-1 level and decreases serum cardiac troponin-I level compared with control subjects and nonmetformin treated patients. Conclusion. Metformin pharmacotherapy increases omentin-1 serum levels and may be regarded as a potential agent in the prevention of the occurrences of acute MI in diabetic patients.

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Prevalence of cardiovascular risk factors and management practices of acute coronary syndrome in a tertiary care hospital

Cited by 9 publications

References 14 publications

Management of acute coronary syndrome in emergency departments: a cross sectional multicenter study (Tunisia)

Management of acute coronary syndrome in emergency departments: a cross sectional multicenter study (Tunisia)

Good Practices in the Clinical Management of Patients with Acute Coronary Syndrome: Retrospective Analysis in a Third-Level Hospital in Mexico

New Insights into the Role of Metformin Effects on Serum Omentin-1 Levels in Acute Myocardial Infarction: Cross-Sectional Study

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