Prevalence of Dementia Subtypes in El Prat de Llobregat, Catalonia, Spain: The PRATICON Study

Gascón‐Bayarri, Jordi; Rizzoli, René; Barrio, José Luis del; Pedro‐Cuesta, Jesús de; Ramón, Juan; Manubens, J.M.; Sánchez, Clara I.; Hernández, Mireia; Estela, J.; Juncadella, Montserrat; Rubio, Francis

doi:10.1159/000108597

Cited by 72 publications

(69 citation statements)

References 91 publications

(85 reference statements)

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“…AD was diagnosed in 63.7% of the cases, a result similar to those obtained by other studies that have shown AD to affect more than 50% of cases of individuals aged 65 or more years [6,28], and more than 60% among still older age groups [38,39]. As the study population comprised a high percentage of individuals over 80 years old, this would explain the similarity with the results of studies of groups of more advanced age.…”

Section: Discussionsupporting

confidence: 87%

“…The prevalence in the most advanced age groups was higher than obtained in Brazilian population-based studies [28,30]. The hypothesis that population-based studies for the older elderly underrepresent and consequently underestimate the prevalence of dementia should be considered, because adhesion to the research and accurate diagnosis are both difficult in this age group due to the greater frequency of physical limitations and comorbidities [38]. In this study, 36.1% of the participants underwent clinical evaluation in the home environment, a larger percentage than described by another study with a similar data collection strategy [28]; this ensured greater participation by the older elderly who tend to refuse, as well as by those at advanced stages of the disease.…”

Section: Discussionmentioning

confidence: 99%

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Prevalence of Dementia in Elderly Clients of a Private Health Care Plan: A Study of the FIBRA-RJ, Brazil

Ribeiro¹,

Lopes²,

Lourenço³

2013

Dement Geriatr Cogn Disord

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Aims: To describe the overall prevalence of dementia syndrome and its major subtypes among elderly clients of a private health care plan and to ascertain the association between this syndrome and socioeconomic characteristics. Methods: A survey was organized in two stages: screening for cognitive impairment and diagnostic evaluation. The study population comprised 683 elderly subjects (aged >67 years), an expanded sample of 7,486 individuals, of the database of the FIBRA-RJ, which evaluated clients of a private health care plan residing in northern districts of the municipality of Rio de Janeiro, Brazil. The diagnosis of dementia was obtained according to DSM-IV criteria. Results: A total of 115 individuals were diagnosed with dementia, resulting in a prevalence of 16.9% (95% CI = 14.4–19.8). The association was strongest among older age groups, i.e. 85–89 years old (prevalence ratio = 8.85; 95% CI = 2.11–37.11) and 90 or more years old (prevalence ratio = 8.85; 95% CI = 2.11–37.11), and among illiterate people (prevalence ratio = 2.77; 95% CI = 1.07–7.19). Sex, personal income and marital status displayed no association with dementia. Conclusion: The prevalence of dementia was higher than found by population-based studies. These findings point to a possibility of a high demand for specialized services among older adults served by the private health care sector.

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Section: Discussionsupporting

confidence: 87%

Section: Discussionmentioning

confidence: 99%

Prevalence of Dementia in Elderly Clients of a Private Health Care Plan: A Study of the FIBRA-RJ, Brazil

Ribeiro¹,

Lopes²,

Lourenço³

2013

Dement Geriatr Cogn Disord

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“…The higher prevalence of CIND in women compared to men (43.5 vs. 50.7%, respectively) corroborates the findings by Nunes et al [19] (14.2 vs. 9.5%, respectively) and other studies [29,30]. Considering dementia, a difference in the prevalence between genders (3.05% in men vs. 4.82% in women over 60 years) was also reported by the Framingham Study [31] as well as by many others [12,32,33]. …”

Section: Discussionsupporting

confidence: 89%

Prevalence and Clinical Predictors of Cognitive Impairment in Individuals Aged 80 Years and Older in Rural China

Shi

Zhang²,

Yue³

et al. 2013

Dement Geriatr Cogn Disord

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Aims: The aim of this study was to estimate the prevalence of cognitive impairment (CI) in individuals aged 80 years and over in rural China and to analyze the associated risk factors. Methods: We conducted a two-phase door-to-door survey of a population in rural Ji County (China). The reference population consisted of individuals aged 80 years or older. A total of 723 individuals were interviewed in their homes, and demographic variables and comorbidities were recorded. Diagnoses were divided into the following 3 categories: normal cognitive function, cognitive impairment no dementia (CIND), and dementia. The odds ratio for each risk factor was calculated by logistic regression analysis. Results: The prevalence of CI among individuals aged 80 years and older was 73.2% (47.4% CIND and 25.7% dementia). The risk of CI decreased with a higher level of education and a higher level of social involvement. The risk of CI was higher in females than in males and among people with a history of stroke (p < 0.01). Conclusions: The observed raw prevalence of CI was 73.2%. Female gender and a history of a previous stroke increased the risk of CI, while a higher educational level and engagement in social activities reduced the risk of CI.

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“…This α-synuclein protein aggregate is thought to disturb neurotransmitter release of acetylcholine (Ach) and dopamine (DA) and lead to dysfunction of the corticosubcortical network [4, 5]. DLB is the second most common type of degenerative dementia after Alzheimer disease (AD), accounting for 10–20% of all dementia cases [6, 7]. The diagnosis of DLB was made using criteria mostly based on clinical symptoms.…”

Section: Introductionmentioning

confidence: 99%

EEG Resting-State Networks in Dementia with Lewy Bodies Associated with Clinical Symptoms

et al. 2019

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Background: Dementia with Lewy bodies (DLB) is characterized by progressive cognitive decline, fluctuating cognition, visual hallucinations, rapid eye movement sleep behavior disorder, and parkinsonism. DLB is the second most common type of degenerative dementia of all dementia cases. However, DLB, particularly in the early stage, is underdiagnosed and sometimes misdiagnosed with other types of dementia. Thus, it is of great interest investigating neurophysiological markers of DLB. Method: We introduced exact low-resolution brain electromagnetic tomography (eLORETA)-independent component analysis (ICA) to assess activities of 5 electroencephalography (EEG) resting-state networks (RSNs) in 41 drug-free DLB patients. Results: Compared to 80 healthy controls, DLB patients had significantly decreased activities in occipital visual and sensorimotor networks, where DLB patients and healthy controls showed no age dependences in all EEG-RSN activities. Also, we found correlations between all EEG-RSN activities and DLB symptoms. Specifically, decreased occipital α activity showed correlations with worse brain functions related to attention/concentration, visuospatial discrimination, and global cognition. Enhanced visual perception network activity correlated with milder levels of depression and anxiety. Enhanced self-referential network activity correlated with milder levels of depression. Enhanced memory perception network activity correlated with better semantic memory, visuospatial discrimination function, and global cognitive function as well as with severer visual hallucination. In addition, decreased sensorimotor network activity correlated with a better semantic memory. Conclusion: These results indicate that eLORETA-ICA can detect EEG-RSN activity alterations in DLB related to symptoms. Therefore, eLORETA-ICA with EEG data can be a useful noninvasive tool for sensitive detection of EEG-RSN activity changes characteristic of DLB and for understanding the neurophysiological mechanisms underlying this disease.

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Prevalence of Dementia Subtypes in El Prat de Llobregat, Catalonia, Spain: The PRATICON Study

Cited by 72 publications

References 91 publications

Prevalence of Dementia in Elderly Clients of a Private Health Care Plan: A Study of the FIBRA-RJ, Brazil

Prevalence of Dementia in Elderly Clients of a Private Health Care Plan: A Study of the FIBRA-RJ, Brazil

Prevalence and Clinical Predictors of Cognitive Impairment in Individuals Aged 80 Years and Older in Rural China

EEG Resting-State Networks in Dementia with Lewy Bodies Associated with Clinical Symptoms

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