Prevalence of dental fluorosis among primary school children in association with different water fluoride levels in Mysore district, Karnataka

Sebastian, Shibu Thomas; Soman, Rino Roopak; Siddanna, Sunitha

doi:10.4103/0970-9290.183126

Cited by 22 publications

(17 citation statements)

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“…In the current study, 34.9% of the study participants had mild fluorosis, a similar finding was reported by Idon PI et al 28 where 32.1% participants reported mild fluorosis. A contrasting finding of 18.5% mild fluorosis was found in a study done by Sebastian ST et al 29 , which coincides with the findings by Chaudhry M et al 30 . Dental fluorosis is mainly because of the concentration of fluoride in drinking water which varies with geography, hence the reason for contrasting results.Tamil Nadu is one of the 19 states with high fluoride contamination in drinking water, varying from 1.0 -48 mg per litre 31 .…”

Section: Resultssupporting

confidence: 76%

Correlation of Dental Fluorosis with Dental Caries among Adult Population Attending A Private Dental College in Chennai

2020

IJFMT

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Fluoride is known as a double edged sword, for both its anticariogenic activity and dental fluorosis in excessive exposure. Results on whether dental caries and dental fluorosis are positively correlated or negatively correlated vary among different researches, thus making it an unsolved area. Hence this study aims to correlate dental fluorosis to dental caries among the adult population attending a private dental college in Chennai.The study includes 258 participants aged 18 years and above, with dental fluorosis. Recorded data was retrieved from patient records in Saveetha Dental College. Record details related to the number of carious lesions present was analysed and Dean's Fluorosis Index (1942) was used to assess the severity of fluorosis among the study population. Descriptive statistics and Pearson correlation were used to analyze the data. Among the participants, 36.4% had carious lesions ranging between 2-3, followed by 27% having more than 4 carious lesions. Mild form of fluorosis was seen among 34.8% of the study population, 9.3% experienced a severe form of fluorosis. Weak correlation between dental caries and dental fluorosis was found at r = 0.03. For the study population, weak correlation between dental fluorosis and dental caries were found, though prevalence of fluorosis was high among the participants. Given the prevalence of fluorosis, defluoridation of water should be considered as a priority.

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Section: Resultssupporting

confidence: 76%

Correlation of Dental Fluorosis with Dental Caries among Adult Population Attending A Private Dental College in Chennai

2020

IJFMT

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“…The prevalence of Dental fluorosis among school children in rural areas of Koppal district was 2279 (74.8%), which is very high compared to other studies done both within and outside India during different time periods 11,[13][14][15][16][17][18] and majority of them have used the same Dean's fluorosis to detect Dental Fluorosis. However, a couple of studies done in Rajasthan 19 and Karnataka 20 have found prevalence of Dental fluorosis in their studies comparable to the present study.…”

Section: Discussionmentioning

confidence: 83%

“…Minimum sample size calculated was 2166 with absolute precision of 3% and significance level of 0.05 and design effect of 2, taking 42% prevalence of Dental fluorosis in Karnataka 11 as per recent estimates. We included 3047 school children aged between 6 years to 12 years in the present study.…”

Section: Sample Sizementioning

confidence: 99%

Prevalence of dental fluorosis and its determinants among primary school children in Koppal district, Karnataka: A cross-sectional study

YAnilkumar¹,

Nimbannavar²,

Mane³

et al. 2020

IJFCM

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Introduction:Fluorosis is an important public health problem across the globe. Intake of Fluoride higher than the optimum level is the main reason for occurrence of Dental and Skeletal Fluorosis. School going children are most commonly affected by Dental Fluorosis. Objectives: 1): To estimate the prevalence of Dental fluorosis among primary school children aged 6-12 years in rural areas of Koppal district. 2): To determine various factors associated with Dental fluorosis in children. Material and Methods: A community based cross-sectional study was conducted in rural areas of Koppal district. A total of 3047 school children in the age group of 6-12 years were included in the study by cluster sampling technique. Dental Fluorosis was identified and graded using Modified Dean's Flurosis Index and data were collected using a pretested and semi-structured questionnaire. Statistical analysis was done using WHO Epi info software version 3.5.4. Results: The Prevalence of Dental Fluorosis among school children in Koppal district was 2279 (74.8%) as per Modified Dean's Fluorosis Index and it was found to be significantly associated with type of diet and source of drinking water among them. Conclusion:The present study concludes that the prevalence of Dental Fluorosis was high in Koppal district and was associated with age, was more in children on mixed diet and drinking ground water.

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“…Dental fluorosis is a disturbance in tooth formation caused by the excessive intake of fluoride during the formative period of dentition, and results in the mottling of dental polish, hard and fragile [13,14]. The most severe manifestation of fluorosis is bone damage which features osteosclerosis, ligament calcifications, and often osteoporosis, osteomalacia, or osteopenia [15,16].…”

Section: Introductionmentioning

confidence: 99%

iTRAQ-Based Proteomics Analysis of Serum Proteins in Wistar Rats Treated with Sodium Fluoride: Insight into the Potential Mechanism and Candidate Biomarkers of Fluorosis

Yan

Zeng

Zhang

et al. 2016

IJMS

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Fluorosis induced by exposure to high level fluoride is quite widespread in the world. The manifestations of fluorosis include dental mottling, bone damage, and impaired malfunction of soft tissues. However, the molecular mechanism of fluorosis has not been clarified until now. To explore the underlying mechanisms of fluorosis and screen out serum biomarkers, we carried out a quantitative proteomics study to identify differentially expressed serum proteins in Wistar rats treated with sodium fluoride (NaF) by using a proteomics approach of isobaric tagging for relative and absolute quantitation (iTRAQ). We fed Wistar rats drinking water that had 50, 150, and 250 mg/L of dissolved NaF for 24 weeks. For the experimental duration, each rat was given an examination of the lower incisors to check for the condition of dental fluorosis (DF). By the end of the treatment, fluoride ion concentration in serum and lower incisors were detected. The results showed that NaF treatment can induce rat fluorosis. By iTRAQ analysis, a total of 37 differentially expressed serum proteins were identified between NaF-treated and control rats. These proteins were further analyzed by bioinformatics, out of which two proteins were validated by enzyme-linked immunoadsorbent assays (ELISA). The major proteins were involved in complement and coagulation cascade, inflammatory response, complement activation, defense response, and wound response, suggesting that inflammation and immune reactions may play a key role in fluorosis pathogenesis. These proteins may contribute to the understanding of the mechanism of fluoride toxicity, and may serve as potential biomarkers for fluorosis.

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Prevalence of dental fluorosis among primary school children in association with different water fluoride levels in Mysore district, Karnataka

Abstract: A significantly positive correlation was found between CFI and water fluoride concentration in drinking water.

Cited by 22 publications

References 0 publications

Correlation of Dental Fluorosis with Dental Caries among Adult Population Attending A Private Dental College in Chennai

Correlation of Dental Fluorosis with Dental Caries among Adult Population Attending A Private Dental College in Chennai

Prevalence of dental fluorosis and its determinants among primary school children in Koppal district, Karnataka: A cross-sectional study

iTRAQ-Based Proteomics Analysis of Serum Proteins in Wistar Rats Treated with Sodium Fluoride: Insight into the Potential Mechanism and Candidate Biomarkers of Fluorosis

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