Prevalence of diabetes in patients with myocardial infarction: a study in a tertiary care centre

Mohanty, Lalatendu; Sahoo, Debananda; Meher, Dayanidhi; Sahoo, Panchanan

doi:10.18203/2349-3933.ijam20163186

Cited by 4 publications

(3 citation statements)

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“…These factors include obesity, hypertension, hyperglycemia, proteinuria, a sedentary lifestyle, and dyslipidemia. 3 Individuals diagnosed with pre-diabetes and type 2 diabetes often demonstrate the presence of insulin resistance, a physiological aberration affecting the utilisation of glucose inside their bodies. It often occurs in groups with high blood pressure, central obesity, raised total triglyceride levels, low HDL cholesterol levels, and hemostatic problems.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Tumor Necrosis Factor Alpha, Insulin, glucose, HbA1c% and HOMA-IR as Predictors for Cardiovascular Diseases in Patients with Type 2 Diabetes

Jabber,

Charfeddine,

Abbas

2024

Pharmacogn J.

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Objective: Comparison of the blood level of TNFα in patients with and without type 2 diabetes who have cardiovascular diseases. Examine the connection between the amount of serum TNFα and insulin resistance in patients with type 2 diabetes who have cardiovascular diseases. Method: The present study included 60 patients with Diabetes Mellitus (DM) with a mean age of 56.02±1.395 years and an age range of (40 -80)years and 60 patients with cardiovascular diseases and diabetes (CVD and DM) with a mean age of 59.20±1.478 and an age range of (40-80) years, Who visited Al-Basrah Teaching Hospital in Basrah. in addition, the study included 60 healthy controls mean age of healthy control subjects was 54.72±1.405years. All patients in this study were diagnosed by specialized doctors and the diagnosis was verified by clinical and laboratory tests, during the period from September 2022 to September 2023. All Subjects signed a written informed consent form. The BMI was calculated as body weight (kg) and was divided by squared height in meters. Results: The results of this study showed an increase in the level of glucose, haemoglobin A1c%, insulin, and HOMA IR (in CVD and DM patients as compared with DM patients and control and there was a significant difference in concentrations among study groups (p-value <0.0001). Also, The results of this study showed an increase in the level of tumor necrosis factor-alpha in CVD and DM patients as compared with DM and control and there was a significant difference in concentrations of TNFα among study groups (p-value <0.0001). Conclusion: Based on the findings of this research, it can be inferred that TNFα and HbA1c have the potential to serve as practical and straightforward indicators for predicting the coexistence of insulin resistance, dysglycemia, and Cardiovascular Diseases in seemingly healthy individuals within the young (<50 years) Al-Basra community.

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Section: Introductionmentioning

confidence: 99%

Evaluation of Tumor Necrosis Factor Alpha, Insulin, glucose, HbA1c% and HOMA-IR as Predictors for Cardiovascular Diseases in Patients with Type 2 Diabetes

Jabber,

Charfeddine,

Abbas

2024

Pharmacogn J.

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“…There are several factors have been recognized, including obesity, hypertension, hyperglycemia, proteinuria, sedentary lifestyle and dyslipidemia that contribute to the cardiovascular risk among T2DM patients. 2,3 Obesity is strongly associated with inflammation and insulin insensitivity that leads to a lack of insulin action on the main insulin-sensitive tissues like adipose tissue, muscle, and liver. Insulin resistance induces both intra-arterial inflammation and extravascular stimuli, which consequently lead to the secretion of proinflammatory cytokines, that in turn promote the pathogenesis of CVD.…”

Section: Introductionmentioning

confidence: 99%

Predictor for cardiovascular risk in patients with type-2 diabetes mellitus

Azharuddin

Kapur

Mishra

et al. 2021

Clinical Epidemiology and Global Health

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Thelimited information available concerning the role of periostin associated with cardiovascular risk in patients with type 2 diabetes mellitus (T2DM). Therefore, this study aimed to find out the association between periostin level and inflammatory markers in patients with T2DM as well as in the acute coronary syndrome (ACS) patients. Methods: This cross-sectional study randomly included a total of 210 participants, comprising T2DM (n = 130), ACS (n = 40), and healthy group (n = 40). All anthropometric measures and biochemical parameters, periostin level, high sensitivity C-reactive protein (hs-CRP), and white blood cell (WBC) count were estimated. Pearson's correlation and linear multiple regression analysis was performed to assess the correlation and association between periostin level and other variables. Results: Serum periostin levels were significantly higher among obese T2DM and ACS patients as compared to control. Positive correlation was found between serum periostin levels and waist circumference (WC), body mass index (BMI), fasting plasma glucose (FPG), postprandial glucose (PPG), glycated hemoglobin (HbA1c), triglyceride (TG), total cholesterol (TC), hs-CRP, WBC count, while negative correlation was observed with high-density lipoprotein (HDL) (p < 0.05). After adjustment, regression analysis showed that BMI, HbA1c, TC, HDL, WBC and hs-CRP were independently related to serum periostin levels (p < 0.001). Conclusion:The evidence of current study suggested that periostin levels were significantly higher among patients with ACS and obese T2DM, and it is significantly associated with lipid profile, anthropometric measures and inflammatory biomarkers. Our results revealed that periodic estimation of the circulating serum periostin could be a biomarker to predict the risk of developing cardiovascular complications in patients with T2DM. However, lacking of follow-up it further creates room for the future investigation.

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“…Forty one (52%) patients with diabetes were men, and 38 (48%) were women (33). A more recent study was conducted by Lalatendu et al(34) at Kalinga Institute of Medical Sciences, Bhubaneswar, Odisha, India, aiming to find the…”

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confidence: 99%

Frequency of Type II Diabetes Mellitus In ST Segment Elevated MI Patients Presented to French Medical Institute for Mothers and Children: A Cross Section Study

Darmal¹

2022

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Background: A significant risk of atherosclerosis is diabetes mellitus which ultimately induces cardiovascular disease, mainly affecting coronary arteries. Patients with diabetes have a risk for coronary events similar to those without diabetes who have already had an event, and conversely, many patients with established coronary artery disease have diabetes or prediabetes. The study looks at the frequency of diabetes mellitus in patients presenting with the acute coronary syndrome in the French Medical Institute. Methods: A cross-sectional study design was utilized to conduct this study. Three hundred twenty-one individuals with acute myocardial infarction (AMI) were screened and presented to the Department of Cardiology of the French Medical Institute for Mothers and Children in Kabul, Afghanistan, from January 1, 2019, to December 30, 2019. All patients of any gender with ST Elevated Myocardial Infarction (STEMI) were included in the study and presented to our setting during the study period. Data were collected retrospectively from the patients' medical record files and then analyzed by logistic regression to look for results. Results: Three hundred twenty-one patients were included in the study, 250 (78%) were males, and 71 (22%) were females. The mean age of the study participants was 57.5 years. The frequency of diabetes mellitus was 26%. There is a strong association between Killip classes and diabetic status (p-value=<0.04). Hypertension and heart failure were not significantly associated with diabetes in STEMI patients. Conclusion:The frequency of diabetes mellitus in this study was significant as one out of every four patients with the acute coronary syndrome was diabetic.

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Prevalence of diabetes in patients with myocardial infarction: a study in a tertiary care centre

Cited by 4 publications

References 0 publications

Evaluation of Tumor Necrosis Factor Alpha, Insulin, glucose, HbA1c% and HOMA-IR as Predictors for Cardiovascular Diseases in Patients with Type 2 Diabetes

Evaluation of Tumor Necrosis Factor Alpha, Insulin, glucose, HbA1c% and HOMA-IR as Predictors for Cardiovascular Diseases in Patients with Type 2 Diabetes

Predictor for cardiovascular risk in patients with type-2 diabetes mellitus

Frequency of Type II Diabetes Mellitus In ST Segment Elevated MI Patients Presented to French Medical Institute for Mothers and Children: A Cross Section Study

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