Prevalence of dry eye syndrome at patients with diabetus melitus tip 2, one year retrospective study May 2011-June 2012

Burda, Nora; Mema, Vilma; Mahmudi, Ejup; Selimi, Brikena; Zhugli, Sulejman; Lenajni, Basri; Bunjaku, Illaz

doi:10.1016/s2221-6189(13)60026-8

Cited by 6 publications

(10 citation statements)

References 10 publications

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“…9,10 For patients with T2DM, the prevalence of DES among Western populations is up to 54.3%, which has consistently been shown to be higher than that among the corresponding general population. 11,12 However, there is currently no comparable data set in the Hong Kong Chinese populations where the overall prevalence of T2DM is around 10%, and increasing up to 20% in those aged over 65 years. 1,13 Studies have shown that, for the same body mass index (BMI), Asians have a higher prevalence of T2DM than the Western populations.…”

Section: Introductionmentioning

confidence: 99%

Association of long‐term glycaemic control on tear break‐up times and dry eye symptoms in Chinese patients with type 2 diabetes

Mak

Shih

et al. 2018

Clinical Exper Ophthalmology

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Section: Introductionmentioning

confidence: 99%

Association of long‐term glycaemic control on tear break‐up times and dry eye symptoms in Chinese patients with type 2 diabetes

Mak

Shih

et al. 2018

Clinical Exper Ophthalmology

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“…Corneal nerve damage may serve as an early indicator in DM [63,[97][98][99]. The prevalence of corneal neuropathy in diabetic patients is approximately 50% [32,[100][101][102][103]. However, corneal neuropathy, as a manifestation of DM, is underrated due to the absence of ocular discomfort and pain [33,98,103,104].…”

Section: Discussionmentioning

confidence: 99%

High Molecular Weight Hyaluronan Promotes Corneal Nerve Growth in Severe Dry Eyes

Setten

Stachs

Dupas

et al. 2020

JCM

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The purpose of this study was to investigate the effect of high molecular weight hyaluronan (HMWHA) eye drops on subbasal corneal nerves in patients suffering from severe dry eye disease (DED) and to evaluate the damage of subbasal corneal nerves associated with severe DED. Designed as an international, multicenter study, 16 patients with symptoms of at least an Ocular Surface Disease Index (OSDI) score of 33, and corneal fluorescein staining (CFS) of at least Oxford grade 3, were included and randomized into two study arms. The control group continued to use their individual optimum artificial tears over the study period of eight weeks; in the verum group, the artificial tears were substituted by eye drops containing 0.15% HMWHA. At the baseline visit, and after eight weeks, the subbasal nerve plexus of 16 patients were assessed by confocal laser scanning microscopy (CSLM). The images were submitted to a masked reading center for evaluation. Results showed a significant increase of total nerve fiber lengths (CNFL) in the HMWHA group (p = 0.030) when compared to the control group, where the total subbasal CNFL did not significantly change from baseline to week 8. We concluded that in severe DED patients, HMWHA from topically applied eye drops could cross the epithelial barrier and reach the subbasal nerve plexus, where it exercised a trophic effect.

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“…Similar significant increase in dry eye syndrome with progressing age and duration of Type 1 and Type 2 DM as observed by us was also reported by others. 29,30,33 However, other researchers failed to show any such correlation. 34 There was no significant difference between dry eye syndrome prevalence between patients having Type 1 and Type 2 diabetes.…”

Section: Rose Bengal Dye Staining Followed By Van Bijsterveld Scorinmentioning

confidence: 97%

“…27,28 Assessment of dry eye syndrome using standard diagnostic tests such as Schirmer 1, Schirmer 2 tests, TFBUT and Rose Bengal staining showed frequencies of dry eye syndrome in Type 1 and Type 2 diabetic patients that were concordant with other researchers. 29,30 However, some studies showed difference in frequencies. 31,32 probably accounting for regional variations or difference in detection methods.…”

Section: Rose Bengal Dye Staining Followed By Van Bijsterveld Scorinmentioning

confidence: 99%

Prevalence of Dry Eye Syndrome in Patients With Type 1 and Type 2 Diabetesa Comparative Study

Das¹,

Sasmal²,

Rana³

2017

jebmh

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BACKGROUND Diabetes mellitus (DM) is a major cause of various ocular complications including Keratoconjunctivitis sicca resulting in tear film deficiency, significantly hindering the performance of daily life and may lead to blindness in severe cases. The objective of our study was to understand the association between Type 1 and Type 2 diabetes mellitus (DM) and development of dry eye syndrome. MATERIALS AND METHODS A pair of eyes of 40 patients with Type 1 DM and 60 patients with Type 2 DM was tested for dry eye syndrome using standard scores from Schirmer test 1, 2, tear film break-up time and Rose Bengal staining. Results were statistically analysed to understand significant association. RESULTS Patients with both types of DM belonged to middle or older age groups. Dry eye syndrome was present in nearly half of the patients, as assessed by different techniques. Dry eye syndrome was significantly increased with progressing age and duration of DM of both types in patients. There was, however, no significant difference in prevalence of dry eyes between patients with Type 1 and Type 2 DM. CONCLUSION Dry eye syndrome is an important comorbidity of DM and progresses with age and duration of the disease, and needs early detection and therapeutic management.

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Prevalence of dry eye syndrome at patients with diabetus melitus tip 2, one year retrospective study May 2011-June 2012

Cited by 6 publications

References 10 publications

Association of long‐term glycaemic control on tear break‐up times and dry eye symptoms in Chinese patients with type 2 diabetes

Association of long‐term glycaemic control on tear break‐up times and dry eye symptoms in Chinese patients with type 2 diabetes

High Molecular Weight Hyaluronan Promotes Corneal Nerve Growth in Severe Dry Eyes

Prevalence of Dry Eye Syndrome in Patients With Type 1 and Type 2 Diabetesa Comparative Study

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