Prevalence of glutamic acid decarboxylase antibodies amongst young Malaysian diabetics

Low prevalence of autoimmune diabetes markers in a mixed ethnic population of Singaporean diabetics

“…The prevalence of GADab in type 1 diabetics re‐affirmed a low frequency reported previously on Singaporean Chinese 13 . A similar prevalence (35.3%) for type 1 diabetics, with equivalent frequencies between Chinese, Indians and Malays was also reported in Malaysia 26 . IA‐2ab frequency in Singaporeans with type 1 diabetes was higher than reported for Filipinos 16 and Malaysians, 17 but lower than that quoted for newly ­diagnosed Caucasians 27 and Japanese 28 .…”

Autoantibodies to GAD and IA‐2 in Saudi Arabian diabetic patients

“…These markers have proved to be valuable in other ethnic populations, particularly the numerous studies in western European and North American populations where GADA and IA-2A have been detected in > 80% and > 70% of newly diagnosed T1DM patients, respectively, using sensitive radio-immunoprecipitation (RIP) assays [1]. A lower prevalence of GADA has been reported in some racial/ethnic patient groups [8][9][10], but this may be related to variations in the assays employed, age of onset and disease duration, as well as possible influences of genetic or environmental factors. The prevalence of IA-2A in T1DM patients from non-Caucasian populations has not yet been thoroughly investigated.…”

Autoantibodies to glutamic acid decarboxylase in diabetic patients from a multi‐ethnic Australian community: the Fremantle Diabetes Study

“…These data have been derived largely from the study of northern European subjects with acute‐onset diabetes. There is a lower prevalence of GADA positivity in Type 1 diabetes in other racial/ethnic groups, including Italians (65%)[5], Japanese (35%)[6], Malaysians (36%)[7], Koreans (30%)[8] and Chinese (29%)[9]. The prevalence of anti‐ICA512/IA2 in Type 1 diabetic patients from non‐Caucasian populations is unknown.…”