Prevalence of Helicobacter Pylori among Dyspeptic Patients

Saeed, Ali Yahya; Pedawi, Safar Mohammad

doi:10.17656/jzs.10099

Cited by 3 publications

(2 citation statements)

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“…H. pylori becomes widely distributed throughout the world including Kurdistan region of Iraq in which studies had found that 65% of the dyspeptic patients were positive for H. pylori by culture [4] and 70.93% seropositive by ELISA IgG [5]. Antimicrobial drugs are extensively and empirically used for the treatment of H. pylori infections using different antimicrobial drugs.…”

Section: Discussionmentioning

confidence: 99%

“…This bacterium can remain asymptomatic or can cause gastritis, gastric and duodenal ulcer and mucosa-associated lymphoid tissue lymphoma [3]. H. pylori is widespread in Kurdistan region of in which 65% of dyspeptic patients were positive for H. pylori by culture [4] and 70.93% by ELISA IgG [5]. Therefore, it has a significant health problem which requires eradication by using antimicrobial drugs [6,7].…”

Section: Introductionmentioning

confidence: 99%

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Antimicrobial Resistance Profile of Helicobacter pylori Clinical Isolates in Duhok City, Kurdistan Region/Iraq

Saeed¹,

Odeesh²,

Abdulhafith³

et al. 2014

IOSRJDMS

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Studies have been referred to the increasing the numbers of H. pylori isolates against antibiotics in the world and account for recurrent and unresponsiveness of many cases of infections. In Iraq, particularly Kurdistan region there are no data regarding the antibiotic resistance profile of H. pylori isolated from clinical cases.The purpose of this work was to investigate the antimicrobial resistance profile of H. pylori isolates from clinical cases against clarithromycin, levofloxacin, amoxicillin, metronidazole, ciprofloxacin and tetracycline. In this study 150 antral biopsies were sampled from patients referred to the Duhokhepatology and gastroenterology center, Azadi Teaching Hospital, Duhok, Kurdistan Region, Iraq for endoscopy examination between March and May, 2014. H. pylori was isolated from 30 (20%) out of 150 patients and their antimicrobial susceptibility were checked by disc diffusion assay. All isolates were susceptible to levofloxacin but with variable resistance patterns to metronidazole, tetracycline, ciprofloxacin, clarithromycin and amoxicillin which were 53.3%, 16.6%, 13.4%, 10% and 6.7% respectively. The patterns of resistance were differed from resistance to 4 combined antimicrobial agents to 2 combined antimicrobial agents. Conclusions: A high percentage of resistance to metronidazole was detected and it should be considered when prescribing drugs to the patients by the clinicians. Periodic evaluation the antimicrobial resistance profile of H. pylori clinical isolates against commonly prescribed drugs in order to prevent generation of resistant strains and to choose the most effective therapeutic strategy in the area.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Antimicrobial Resistance Profile of Helicobacter pylori Clinical Isolates in Duhok City, Kurdistan Region/Iraq

Saeed¹,

Odeesh²,

Abdulhafith³

et al. 2014

IOSRJDMS

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Laboratory diagnosis of H. pylori among dyspeptic patients using Culture and Rapid urease test

Saadi

Saeed

2019

KJAR

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Globally Helicobacter pylori has been defined is the prime reason of stomach ulcer and gastric cancer. Medical laboratory analysis of H. pylori infection is done by two ways invasive and non- invasive methods. Invasive techniques frequently disapproved by patients because it is inconvenient but still remain reliable methods. Among invasive methods, culture is considered as gold standard method from which other methods are compared. A sum of eighty six persons with average of ages between 18-77 years old with mean 37.58 years ± (forty three males , forty three females) who visited to endoscopic center / Azadi Teaching Hospital for endoscopic examination from June to Oct. 2013.From everyone , two antral biopsies, one for urease test, the other for culture were collected. Biographies from each case were taken in a questionnaire form after approval by Research Ethics Committee of the college of medicine / Duhok university. H. pylorus was found in 37.2% and 68% by Culture and Rapid urease test respectively. The biggest value percentage of H. pylori positive cases was detected by rapid urease test while the fewest value percentage was by Culture. Combination of both tests it did not approve as a diagnostic test for detection of this pathogenic bacteria. The study did not detect any statistical correlation on the impact of age factor on H. pylori infection by both methods. In this research appear males were less positive for H. pylori than females by urease test and no such statistical association was noticed count on the sex and Helicobacter pylori pathogenicity via culture. Research never noticed any considerable correlation was found between smoking status and patient's residence with H. pylori positive cases by both methods. This study was performed to estimate the appropriate and better diagnostic tests for diagnosis of H. pylori among various types of samples. Due to the increasing incidence of treatment failure (caused in part by antibiotic resistance), post-treatment testing is recommended to confirm H. pylori eradication. Knowledge of the epidemic and the Routes of transmission of this pathogen are important points to avoid from spreading and may be useful in identifying high-risk populations, especially in areas that have high rates of gastric lymphoma, gastric cancer, and gastric ulcer. The current study concludes (RUT) was superlative than culture for the detection of Helicobacter pylori.

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Antimicrobial Resistance Profile of Helicobacter pylori Clinical Isolates in Duhok City, Kurdistan Region/Iraq

Saeed¹,

Odeesh²,

Abdulhafith³

et al. 2014

View full text Add to dashboard Cite

Prevalence of Helicobacter Pylori among Dyspeptic Patients

Cited by 3 publications

References 5 publications

Antimicrobial Resistance Profile of Helicobacter pylori Clinical Isolates in Duhok City, Kurdistan Region/Iraq

Antimicrobial Resistance Profile of Helicobacter pylori Clinical Isolates in Duhok City, Kurdistan Region/Iraq

Laboratory diagnosis of H. pylori among dyspeptic patients using Culture and Rapid urease test

Antimicrobial Resistance Profile of Helicobacter pylori Clinical Isolates in Duhok City, Kurdistan Region/Iraq

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