Prevalence of helicobacter pylori infection among patients undergoing upper gastrointestinal endoscopy in a medical college hospital in Kerala, India

Adlekha, Shashikant; Chadha, Tandra; Krishnan, Prasad; Sumangala, B

doi:10.4103/2141-9248.122109

Cited by 53 publications

(49 citation statements)

References 15 publications

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“…In Asia, the studies published over the last year showed high prevalence rates of H. pylori infection ranging from 54% to 76% [10][11][12][13][14][15][16]. Only one study carried out on healthy individuals in Saudi Arabia showed a low prevalence of infection of about 28% [17].…”

Section: Prevalence Of Helicobacter Pylori Infectionmentioning

confidence: 99%

“…Gender and age do not seem to be associated with an increased risk of infection. Indeed, most studies reported no significant difference of H. pylori infection between men and women, both in adults [3,13,[15][16][17]20,21] and in children [23,24,27]. No significant association was found between infection and age in the adult population [4,8,13,14,16,17,23].…”

Section: Risk Factors For Helicobacter Pylori Infectionmentioning

confidence: 99%

“…Indeed, most studies reported no significant difference of H. pylori infection between men and women, both in adults [3,13,[15][16][17]20,21] and in children [23,24,27]. No significant association was found between infection and age in the adult population [4,8,13,14,16,17,23]. The age-specific gradient in H. pylori prevalence reported by some studies seems to be related to a birth cohort effect [3,10,20,21,26].…”

Section: Risk Factors For Helicobacter Pylori Infectionmentioning

confidence: 99%

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Epidemiology ofHelicobacter pyloriInfection

2014

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Medline and PubMed databases were searched on epidemiology of Helicobacter pylori for the period of April 2013-March 2014. Several studies have shown that the prevalence of H. pylori is still high in most countries. In north European and North American populations, about one-third of adults are still infected, whereas in south and east Europe, South America, and Asia, the prevalence of H. pylori is often higher than 50%. H. pylori remains highly prevalent in immigrants coming from countries with high prevalence of H. pylori. However, the lower prevalence of infection in the younger generations suggests a further decline of H. pylori prevalence in the coming decades. Low socioeconomic conditions in childhood are confirmed to be the most important risk factors for H. pylori infection. Although the way the infection is transmitted is still unclear, interpersonal transmission appears to be the main route. Finally, H. pylori recurrence after successful eradication can still occur, but seems to be an infrequent event.The epidemiology of Helicobacter pylori has been changing over the last decades, with a decline of the prevalence of the infection in most countries. The changing epidemiology of the bacterium has been associated with a parallel decline in peptic ulcer disease and gastric cancer [1] and may have an impact on the changing epidemiology of other diseases, such as gastroesophageal reflux disease, allergies, and asthma [2].Over the last year, several studies reported data on the prevalence of H. pylori infection in both adults (Table 1) and children (Table 2) in Europe, Canada, Latin America, Asia, and Africa. Prevalence of Helicobacter pylori InfectionIn Europe, the prevalence of H. pylori seems to be lower in Northern countries than in Southern and Eastern countries. In the Netherlands, a randomly selected sample of 1550 blood donors from four different regions was tested for the presence of antibodies against H. pylori and the CagA antigen [3]. In this study, only native Dutch subjects were evaluated excluding non-European immigrants. This study reported a 32% prevalence of H. pylori infection, with 28% of H. pyloripositive subjects carrying a CagA-positive strain. The seroprevalence of H. pylori declined from 48% in subjects born between 1935 and 1946 to 16% in those born between 1977 and 1987, as a likely consequence of a birth cohort effect. Also the proportion of CagApositive subjects decreased from 38% to 14% in the same age cohorts. These data would suggest that a further reduction of H. pylori prevalence in the Netherlands over the coming decades could be expected.Additionally, from the Netherlands, a populationbased prospective study of a cohort of more than 6500 pregnant women was published [4]. This study found that the prevalence of H. pylori in Dutch women was 24%. The most important finding was that the prevalence of H. pylori was much higher in non-Dutch women with 64% of them being H. pylori seropositive. Moreover, in the latter group, infected subjects born abroad (first-generation i...

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Section: Prevalence Of Helicobacter Pylori Infectionmentioning

confidence: 99%

Section: Risk Factors For Helicobacter Pylori Infectionmentioning

confidence: 99%

Section: Risk Factors For Helicobacter Pylori Infectionmentioning

confidence: 99%

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Epidemiology ofHelicobacter pyloriInfection

2014

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“…16 In our study, the presence of H. pylori was 35%; with prevalence being more among alcoholics. The low incidence in our study could be due to the use of only a single method (RUT) to detect H. pylori.…”

Section: Discussionmentioning

confidence: 82%

Clinical and endoscopic evaluation of dyspeptic patients attending a tertiary care hospital in South India: A prospective study

Manappallil

2017

Asian J Med Sci

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Background:The incidence of dyspepsia has been increasing all over the world; with some having an organic cause while others have functional dyspepsia. Helicobacter pylori infection is also a contributory factor. Moreover, these dyspeptic patients also show a wide spectrum of symptoms. Aims and Objective: The aim of this study was to clinically and endoscopically evaluate the patients with dyspepsia; and also to assess the prevalence of Helicobacter pylori. Materials and Methods: A prospective study was conducted on 100 dyspeptic patients who were advised an upper gastrointestinal endoscopy based on clinical grounds at Pondicherry Institute of Medical Sciences, Pondicherry, India. Results: Of the 100 dyspeptic patients evaluated in this study, the mean age was 42 years, with 54% belonging to 20 to 40 years, 35% to 41 to 60 years and 11% above 60 years age groups. 61% were males and 39% females. They belonged to various occupational groups with majority leading a retired life or as homemakers (36%), followed by those with white collar jobs or as students (29%), unskilled workers (26%) and skilled workers (9%). Majority of these patients were non vegetarians (83%). Smokers and alcoholics comprised of 38% and 43% of the subjects respectively; and 31% had history of NSAID consumption. Epigastric pain and epigastric burning sensation were the main complaints among dyspeptic patients. Heartburn was more common among smokers and alcoholics; and epigastric pain among NSAID users. The main endoscopic abnormalities were erythematous and erosive gastritis (42% and 21% respectively), followed by duodenal ulcer (18%) and erosive duodenitis (15%). Duodenal ulcers were more common among males (89%). Duodenitis (89%) and duodenal ulcers (67%) were mainly seen in alcoholics. 18% of our study patients had a normal endoscopic finding. Helicobacter pylori was present in 35% of the subjects. Epigastric pain and epigastric burning sensation were the main symptoms among these patients; with erythematous gastritis being the main endoscopic finding. Conclusion: Dyspepsia was more common among younger age groups. Epigastric pain and epigastric burning sensation were the most common symptoms. Erythematous gastritis followed by erosive gastritis was the common endoscopic abnormality. Some patients also had normal findings on endoscopy.Helicobacter pylori was present in a significant number of patients.

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“…11 The prevalence of H pylori in gastric biopsy is 58.7 % similar to other studies in South India, showing 59.4 % prevalence. 12 According to this study, the sensitivity and specificity of H&E stain were 75.86%, and 98.41%, respectively. This is in concordance with similar studies showing sensitivity of 70% -98 % and specificity of 90-98% with H&E stain .However in cases showing low density of organisms, the specificity of H&E was low compared to Giemsa.…”

Section: Resultsmentioning

confidence: 99%

Role of Special Stain Giemsa in Demonstration of Helicobacter Pylori in Gastric Biopsies

Elias¹

2017

JMSCR

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Prevalence of helicobacter pylori infection among patients undergoing upper gastrointestinal endoscopy in a medical college hospital in Kerala, India

Cited by 53 publications

References 15 publications

Epidemiology ofHelicobacter pyloriInfection

Epidemiology ofHelicobacter pyloriInfection

Clinical and endoscopic evaluation of dyspeptic patients attending a tertiary care hospital in South India: A prospective study

Role of Special Stain Giemsa in Demonstration of Helicobacter Pylori in Gastric Biopsies

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