Prevalence of hepatitis B and human T‐lymphotropic virus infection among blood donors at a hospital in the south‐central highlands of Peru

Ramírez-Soto, Max Carlos; Huichi-Atamari, Milagros

doi:10.1111/tme.12451

Cited by 3 publications

(2 citation statements)

References 4 publications

(7 reference statements)

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“…Similar studies from several blood banks from Medellin observed 0.06-0.176% positivity, mainly for HTLV-1 [243,244]. We also found two studies conducted on blood donors from Peru, Arequipa (0.9% HTLV-1 positive) and Abancay (3.4%, unknown subtype), and one in pregnant women from Lima (1.7% HTLV-1 positive) [253,254,256]. Concerning Chile, 0.12-0.24% HTLV positivity was described, showing higher prevalence in the central region of Valdivia than in Concepcion in the South; together with an almost 3:1 female to male ratio and a 7:1 HTLV-1 to HTLV-2 ratio [265,274].…”

Section: Htlv Prevalence and Morbidity In Latin Americasupporting

confidence: 86%

Lymphotropic Viruses EBV, KSHV and HTLV in Latin America: Epidemiology and Associated Malignancies. A Literature-Based Study by the RIAL-CYTED

Chabay

Lens

Hassan

et al. 2020

Cancers

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The Epstein–Barr virus (EBV), Kaposi sarcoma herpesvirus (KSHV) and human T-lymphotropic virus (HTLV-1) are lymphomagenic viruses with region-specific induced morbidity. The RIAL-CYTED aims to increase the knowledge of lymphoma in Latin America (LA), and, as such, we systematically analyzed the literature to better understand our risk for virus-induced lymphoma. We observed that high endemicity regions for certain lymphomas, e.g., Mexico and Peru, have a high incidence of EBV-positive lymphomas of T/NK cell origin. Peru also carries the highest frequency of EBV-positive classical Hodgkin lymphoma (HL) and EBV-positive diffuse large B cell lymphoma, not otherwise specified (NOS), than any other LA country. Adult T cell lymphoma is endemic to the North of Brazil and Chile. While only few cases of KSHV-positive lymphomas were found, in spite of the close correlation of Kaposi sarcoma and the prevalence of pathogenic types of KSHV. Both EBV-associated HL and Burkitt lymphoma mainly affect young children, unlike in developed countries, in which adolescents and young adults are the most affected, correlating with an early EBV seroconversion for LA population despite of lack of infectious mononucleosis symptoms. High endemicity of KSHV and HTLV infection was observed among Amerindian populations, with differences between Amazonian and Andean populations.

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Section: Htlv Prevalence and Morbidity In Latin Americasupporting

confidence: 86%

Lymphotropic Viruses EBV, KSHV and HTLV in Latin America: Epidemiology and Associated Malignancies. A Literature-Based Study by the RIAL-CYTED

Chabay

Lens

Hassan

et al. 2020

Cancers

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“…In Peru, HTLV-1 infections are reported in 1.2% to 3.4% of potential blood donors [10,50]. Blood products have been screened for HTLV-1 since 1997 in this country, but there is no specific program in pregnant women or neonates.…”

Section: Discussionmentioning

confidence: 99%

Screening for Human T-Cell Lymphotropic Virus (HTLV) in Pregnant Women in the Peruvian Amazon and Systematic Review with Meta-Analysis of HTLV Infection in Peru

et al. 2021

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Background. Human T-cell lymphotropic virus type 1 (HTLV-1) is responsible for tropical spastic paraparesis and HTLV-1-associated leukemia/lymphoma. The infection is endemic in some areas of Peru, but its prevalence in the Peruvian Amazon is not well established. We aimed to assess the seroprevalence of HTLV-1 infection in pregnant women in the Peruvian Amazon. Moreover, we performed a systematic literature review and meta-analysis of the seroprevalence of HTLV infection in Peru. (2) Methods. This is a prospective cross-sectional study involving pregnant women attending health centers in the city of Iquitos, Peru, in May and June 2019. The presence of antibodies against HTLV-1 was assessed using ELISA (HTLV I + II ELISA recombinant v.4.0, Wiener lab, Rosario, Argentina). Positive cases were confirmed by Western Blot and HTLV-1 proviral load. (3) Results. The study included 300 pregnant women with a mean age of 26 years (standard deviation [SD] 6.4). Five patients were diagnosed with HTLV-1 infection (prevalence 1.7%, 95% confidence interval (CI) 0.7% to 3.8%). Pregnant women with HTLV-1 infection were discretely younger (mean age 22.6 [SD 22.6] vs 26.8 [SD 6.3]; p = 0.128). None of the five women had been transfused, and all were asymptomatic. Two (40%) also had a positive serology for Strongyloides, but larvae were not detected in any of the parasitological stool studies. The systematic review component identified 40 studies, which showed that the prevalence of HTLV infection in the general population was 2.9% (95% CI 1.2% to 5.3%) and in women of childbearing age, 2.5% (95% CI 1.2% to 4.0%). (4) Conclusion. The prevalence of HTLV-1 in the Peruvian Amazon basin is about 1.7%, indicating an endemic presence. Screening for HTLV-1 in prenatal care is warranted.

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Public policies on health and housing: factors of radon 222 gas and its effects on lung (Preprint)

Janampa AcuÑa Sr,

CERAFIN URBANO,

CERAFIN URBANO

et al. 2023

Preprint

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UNSTRUCTURED Lung cancer has increased the mortality rate in the population, and radon 222 gas is the second cause of lung cancer after smoking. The purpose of the study was to determine the factors of radon gas that cause effects on lung cancer in cancer patients according to national and international studies. The theoretical analysis methodology allowed reaching the study of publications regarding the study variable from the data found in scientific information organisations such as Pub Med, Scielo, Scopus and scientific method developed by Instituto Sindical de Trabajo, Ambiente y Salud (ISTAS-CCOO) (2019); a total of 56 publications related to the treatment of radon gas as a cause of lung cancer were established. It has been found that the incidence that is translated and concentrated is in the construction areas of granite material, in waste from mining areas, in closed environments, as well as that air is a factor that spreads the gas with higher level and water is a factor of high concentration; but no strong evidence has been demonstrated about the cause of radon gas.

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Prevalence of hepatitis B and human T‐lymphotropic virus infection among blood donors at a hospital in the south‐central highlands of Peru

Cited by 3 publications

References 4 publications

Lymphotropic Viruses EBV, KSHV and HTLV in Latin America: Epidemiology and Associated Malignancies. A Literature-Based Study by the RIAL-CYTED

Lymphotropic Viruses EBV, KSHV and HTLV in Latin America: Epidemiology and Associated Malignancies. A Literature-Based Study by the RIAL-CYTED

Screening for Human T-Cell Lymphotropic Virus (HTLV) in Pregnant Women in the Peruvian Amazon and Systematic Review with Meta-Analysis of HTLV Infection in Peru

Public policies on health and housing: factors of radon 222 gas and its effects on lung (Preprint)

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