Prevalence of Hepatitis-B Surface Antigen (HbsAg), Hepatitis C Virus (HCV) and Human Immunodeficiency Virus (HIV) among Blood Donors in Kano State, Nigeria

Momodu, Imoru; Eke, Christopher Bismarck; Adegoke, AA

doi:10.4314/jmls.v12i1.35276

Cited by 17 publications

(17 citation statements)

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“…This prevalence is similar to 4.6 and 3.8% reported in similar Nigerian studies in Sokoto [41] and Kano [42]. However, lower values of 1 and 2.8% have been reported in Portharcourt [26] and Kaduna [43].…”

Section: Discussionsupporting

confidence: 88%

Seroprevalence of transfusion-transmissible infections (HBV, HCV, syphilis and HIV) among prospective blood donors in a tertiary health care facility in Calabar, Nigeria; an eleven years evaluation

et al. 2018

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BackgroundProvision of constant and safe blood has been a public health challenge in Sub-Saharan Africa with high prevalence of transfusion-transmissible infections (TTIs). This study was aimed at determining the trend and seroprevalence of HBV, HCV, syphilis and HIV across the years within study among prospective blood donors at blood bank in University of Calabar Teaching Hospital (UCTH), Calabar, Nigeria.MethodsA retrospective analysis of blood donor data from January 2005 to December 2016 was conducted in Blood Bank/Donor Clinic of University of Calabar Teaching Hospital, Calabar, Nigeria. Sera samples were screened for hepatitis B surface antigen (HBsAg), antibodies to hepatitis C virus (HCV), human immunodeficiency virus (HIV) 1 and 2 and Treponema pallidum using commercially available immunochromatic based kits.ResultsOut of the 24,979 screened prospective donors in the 2005–2016 study period, 3739 (14.96%) were infected with at least one infective agent. The overall prevalence of HBV, HCV, syphilis and HIV were 4.1, 3.6, 3.1 and 4.2%, respectively. During the period of study, the percentage of all transfusion-transmissible infections declined significantly with remarkable decline in HIV. The study showed male dominated donor pool (98.7%) with higher prevalence (4.2%) of transfusion-transmissible infections than in female donors (0.0%). Commercial donors constituted majority (62.0%) of the donors and as well had the highest prevalence of transfusion-transmissible infections. Majority (62.9%) of the donors were repeat donors.ConclusionHBV, HCV, syphilis and HIV have remained a big threat to safe blood transfusion in Nigeria and Sub-Saharan Africa at large. Strict adherence to selection criteria and algorithm of donor screening are recommended.

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Section: Discussionsupporting

confidence: 88%

Seroprevalence of transfusion-transmissible infections (HBV, HCV, syphilis and HIV) among prospective blood donors in a tertiary health care facility in Calabar, Nigeria; an eleven years evaluation

et al. 2018

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“…Previous studies in different population subgroups in Nigeria, some African and Middle -Eastern countries have recorded varying prevalence rates of HCV (Jeremiah et al, 2008). Just like the prevalence of 0.40% obtained in this study, low HCV prevalence rates were recorded in some studies conducted among blood donors in Kano, Nigeria (0.40%), Namibia (0.90%), Sudan (1.90%), Senegal (0.80%), and Ghana (0.90%), (Jeremiah et al, 2008;Imoru et al, 2003). However, higher prevalence rates were found in studies previously conducted in Nigeria; 4.50%, among sickle cell disease patients with regular blood transfusion in Benin, 5.70%, among HIV patients in Jos, 8%, among university undergraduates in Ilorin, 5%, and 12.30%, in Port-Harcourt and Benin respectively (Nwannadi et .…”

Section: Discussionsupporting

confidence: 72%

Prevalence of Hepatitis C virus antibody among undergraduates in Ogbomoso, Southwestern Nigeria

Jemilohun

Oyelade

Oiwoh

2014

African Journal of Infectious Diseases

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Background: This study was conducted to determine the prevalence of hepatitis C virus antibody (anti-HCV), among a healthy university undergraduate population in south-western Nigeria. Materials and Methods: Relevant medical information of students who underwent the post-admission screening exercise for the year 2012, at the Ladoke Akintola University of Technology (LAUTECH), Health Center, Ogbomoso were extracted from the laboratory log book. All tests were done using rapid anti-HCV test kit by Health -Chem diagnostics, USA. A total of 1,572 students were included in the study. The mean age was 19.61 (± 2.75) years while the age range was 15-50 years. A total of 821 (52.20%), of the subjects were males while 751 (47.80%) were females. More than ninety nine percent (99.90%) of the subjects were aged 15-30 years, whereas those aged ≥31 years were comparatively few (0.60%). Results: Of the 1572 students, 6 tested positive, giving an overall prevalence of 0.40%. Three (0.37%) of the 821 male subjects tested positive while 3(0.40%) also of the 751 female subjects tested positive. Age-group 21-30 years had the highest prevalence of anti -HCV (0.50%), followed by agegroups ≤ 20 years with 0.30% prevalence. None of the subjects in age-groups 31-40 and ≥ 41 years tested positive. Conclusion: These observed differences were not statistically significant. The prevalence of Hepatitis C Virus is low among the young healthy undergraduate population in the south -western region of Nigeria.

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“…Marked variation in the prevalence of HIV antibody of HIV antibody has been reported in different part of Nigeria. Some workers have reported prevalence of HIV to be lower than the 2% found in this study, while others reported higher prevalence of HIV antibody from some locations [18,19,13]. Ejele, et al, [18] found that 4% of blood donors in Port Harcourt, South-Southern Nigeria had HIV antibody.…”

Section: Discussioncontrasting

confidence: 49%

Transfusion transmissible viral infections among potential blood donors in Ibadan, Nigeria

Afolabi¹,

Abraham²,

Oladipo³

et al. 2013

Af J Clin Exp Micro

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It is evident that proper screening procedures prior blood transfusion is a cost-effective approach for prevention and control of transfusion-transmissible infections (TTIs). Also, it has been documented that sub-standard test kits are mostly used in resource limited settings for transfusion related diagnosis. However, the role of such practice in epidemiology of transfusion transmissible viral infections in a tertiary health care facility would give an insight to the rates of blood transfusion associated viral transmission in the community at large. Therefore, the study was designed to determine the prevalence of Human Immunodeficiency Virus (HIV), Hepatitis B and Hepatitis C viruses among blood donors in a tertiary hospital where quality diagnostic procedures are considered prior recruitment of donors. Post ethical approval, counselled and consenting 507(M= 426; F=81) aged 19 to 68 years (Median age:39) potential blood donors were recruited and tested for HIV, HBsAg and anti-HCV using commercial ELISA testkit in strict compliance with the manufacturer'sprocedures. Overall results show rates of 2.0%, 5.9% and 1.4% for HIV, HBsAg and HCV respectively. Also, highest prevalence rates were recorded among age group 26 to 35 years as 2.6%, 7.2% and 2.1% for HIV, HBV and HCV respectively. Furthermore, higher prevalences rates were noted among unmarried individuals as 2.6%, 6.8% and 2.1% for HIV, HBV and HCV respectively.

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Prevalence of Hepatitis-B Surface Antigen (HbsAg), Hepatitis C Virus (HCV) and Human Immunodeficiency Virus (HIV) among Blood Donors in Kano State, Nigeria

Cited by 17 publications

References 0 publications

Seroprevalence of transfusion-transmissible infections (HBV, HCV, syphilis and HIV) among prospective blood donors in a tertiary health care facility in Calabar, Nigeria; an eleven years evaluation

Seroprevalence of transfusion-transmissible infections (HBV, HCV, syphilis and HIV) among prospective blood donors in a tertiary health care facility in Calabar, Nigeria; an eleven years evaluation

Prevalence of Hepatitis C virus antibody among undergraduates in Ogbomoso, Southwestern Nigeria

Transfusion transmissible viral infections among potential blood donors in Ibadan, Nigeria

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