Prevalence of Human Herpesviruses in Patients with Aggressive Periodontitis

Yapar, Mehmet; Saygun, Işıl; Özdemir, Atilla; Kubar, Ayhan; Şahin, Sermet

doi:10.1902/jop.2003.74.11.1634

Cited by 55 publications

(61 citation statements)

References 42 publications

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“…In other research, it has been associated with aggressive and chronic periodontitis (Bilichodmath et al, 2009;Botero et al, 2007;Contreras et al, 2000;Ling et al, 2004, Yapar et al, 2003Saygun et al, 2004). We found that 8% of the individuals in our study from northeastern Mexico suffering from chronic periodontitis had HSV-1 present in the periodontal pockets.…”

Section: Discussionsupporting

confidence: 52%

Identification of Herpes virus in patients with chronic periodontitis from Northeastern Mexico

Mauricio¹,

Ernesto²,

Rosa³

et al. 2013

Afr. J. Microbiol. Res.

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Periodontitis is an inflammatory process that occurs in the tissues surrounding the teeth. It is caused by microorganisms and groups of microorganisms and results in loss of periodontal ligament and alveolar bone. Herpes virus has emerged as a putative pathogen in periodontal disease. Periodontal disease was demonstrated in 50 patients by careful probing of pockets and completion of a medical record. Three saliva samples were collected in individuals with deep pockets. Samples were obtained with a sterile swab and placed in 10% glucose solution for storage at -80°C. DNA purification and PCR, in addition to electrophoresis, were performed. Of the 50 samples processed, two were positive for HSV-1 and two for HSV-2. Three were from women with mild, moderate, and severe chronic periodontitis, respectively, and one (HSV-1) from a man with mild chronic periodontitis. Due to the low prevalence of herpes simplex virus in periodontal pockets, it was not possible to determine its role in the progression of periodontitis.

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Section: Discussionsupporting

confidence: 52%

Identification of Herpes virus in patients with chronic periodontitis from Northeastern Mexico

Mauricio¹,

Ernesto²,

Rosa³

et al. 2013

Afr. J. Microbiol. Res.

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“…This has led many investigators to look for a possible viral cause in the development of aggressive periodontitis. [7] Since the mid1990s viruses have emerged as putative pathogens in aggressive periodontitis, in particular Human cytomegalovirus (HCMV), Epstein-Barr virus (EBV) and Herpes simplex virus-1 (HSV-1). Herpesviruses seem to be the most important DNA viruses in oral pathology.…”

Section: Introductionmentioning

confidence: 99%

Role of herpes simplex-1, epstein barr and human cytomegalo viruses in aggressive periodontitis

Dani¹,

Dwarakanath

Alampalli

et al. 2013

International Journal of Dental Research

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Objectives: Aggressive periodontitis is characterized rapid and severe destruction of the tooth supporting tissues with a complex and unclear etiopathogenesis. The present study was designed to identify the role of herpesviruses in pathogenesis of aggressive periodontitis. Material and methods: Study included 15 subjects diagnosed with aggressive periodontitis (group A) and 15 periodontally healthy subjects (group B). Subgingival plaque was collected from the deepest periodontal pocket and gingival tissue biopsy from the adjacent interdental papilla. Results analyzed by polymerase chain reaction. Results: EBV detected in 67% plaque and 73% tissue samples in group A, 7% plaque and none in the tissue samples in group B. HCMV identified in 53% plaque and 20% of tissue samples in group A, 20% plaque and 7% tissue samples in group B. HSV-1 found in 47% plaque and 13% tissue samples in group A, 13% plaque and 47% tissue samples in group B. Conclusion: An increased prevalence of EBV, HCMV and HSV-1 in group A in comparison to healthy controls was observed. Only EBV showed significant difference between both groups. Despite similarity in pathogenic traits between herpesvirus diseases and Periodontitis, delineating the exact role that viruses play in the etiopathogenesis of aggressive periodontitis is difficult.

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“…In the immuno deficient, B cell clones may replicate unchecked, resulting in lymphomas (Yapar et al, 2003).…”

Section: Pathogenesis (Winkler Et Al 1988; Yapar Et Al 2003)mentioning

confidence: 99%

Role of Viruses in Periodontal Diseases: A Review

Taneja¹,

Kudva²,

Goswamy³

et al. 2017

Int.J.Curr.Microbiol.App.Sci

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Prevalence of Human Herpesviruses in Patients with Aggressive Periodontitis

Abstract: These findings indicate that subgingival presence of EBV-1 HCMV is strongly associated with aggressive periodontitis, and coinfection with HCMV and EBV-1 appears to be particularly deleterious to periodontal health.

Cited by 55 publications

References 42 publications

Identification of Herpes virus in patients with chronic periodontitis from Northeastern Mexico

Identification of Herpes virus in patients with chronic periodontitis from Northeastern Mexico

Role of herpes simplex-1, epstein barr and human cytomegalo viruses in aggressive periodontitis

Role of Viruses in Periodontal Diseases: A Review

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