Prevalence of inappropriate prescribing in primary care

Bregnhøj, Lisbeth; Thirstrup, Steffen; Kristensen, M; Bjerrum, Lars; Sonne, Jesper

doi:10.1007/s11096-007-9108-0

Cited by 58 publications

(63 citation statements)

References 27 publications

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“…In literature are reported dosage errors by 6.7% [7] although the data found in this study is lower than that reported in literature, the consumption of drugs not specified and / or higher than the recommended doses, exposes the EP to the risk of adverse events related to drugs, unwanted physiological responses to exercise, promote drug interactions, adverse reactions and more. Sometimes the EP receives medications for the treatment of acute diseases, but those are included in the prescription and without further review of the evolution of the disease are still prescribed by "repeated formula".…”

Section: Discussioncontrasting

confidence: 67%

“…As evidenced by several studies [5,7,8,12,20,15], consumption of more than 5 medications means a high risk of causing ADR, that added to the result of inappropriate prescribing obtained in this study, half of the population with the methodology STOPP are constantly at risk, because of that, measures must be taken for identification and prevention of PIP. It is proposed to strengthen the integration of clinical services to the pharmaceutical service that also aims to contribute in a harmonious and integral way to improve the quality of individual and collective life under the Health Promotion and Prevention.…”

Section: Discussionmentioning

confidence: 70%

“…[17] This result is high compared with those reported in the literature with values of 12% [5,7] which means that it must be developed a strengthening in the review of all indications of drugs in the EP.…”

Section: Discussionmentioning

confidence: 95%

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Evaluation Of Pharmacotherapy Used On Geriatric Population In An Institution Of Special Regime With The Screening Tool Of Older Persons’ Potentially Inappropriate Prescriptions (STOPP) Criteria

2016

Vitae

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Background: Geriatric patients represent a major challenge for appropriate prescription because they have significant changes in vital areas, multiple comorbidities among other things that encourage their fragility. In light of current evidence, the number of prescription errors increases with age and with the number of drugs USED, showing that people over 65 is at greater risk of medical error when more than 8 drugs are consumed. Objectives: To identify and describe the inappropriate medicines in elderly people in order to propose an institutional prescription guide based on the results of the application of the Screening Tool of Older Persons' Potentially Inappropriate Prescriptions (STOPP) assessment methodology. Methods: A cross-section observational study with a retrospective collection of information was carried out in order to identify the frequency of inappropriate prescriptions in 300 elderly patients that were over 65 years, with a consumption of more than 5 medications and applying the STOPP criteria. The study was made in a special regime medical institution, reviewing medical records and considering variables such as number of medications, indications, dosage, therapeutic duplication, interactions and contraindications, among others. Results: The principal diagnosis was hipertension (47%) followed by diabetes mellitus (10%) and other hypothyroidisms (4%).After applying the STOPP criteria to each of the medical records, it was found that 50.7% (152) of the studied population had at least one inappropriate prescription distributed as follows: 2 prescriptions had 4 STOPP criteria, 7 prescriptions had 3 STOPP criteria, 28 had 2 STOPP criteria and 115 had 1 STOPP criteria. Conclusions: It was found that half of the prescriptions have at least one inadequate prescribed criteria, being the most important the inappropriate use of not indicated drugs or without an indication. Finally, guidelines for the rational use of drugs in the elderly with every detail of this institution are proposed.

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Section: Discussioncontrasting

confidence: 67%

Section: Discussionmentioning

confidence: 70%

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Evaluation Of Pharmacotherapy Used On Geriatric Population In An Institution Of Special Regime With The Screening Tool Of Older Persons’ Potentially Inappropriate Prescriptions (STOPP) Criteria

2016

Vitae

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“…This condition corresponds to the characteristic of the subject (71% were female). In contrast, Reis and Cassiani and Carvalho et al and Bregnhøj et al revealed that potential drug interactions occurred in patients with cardiovascular diseases [7,8,13]. Patients with the pathological condition have an increased risk for drug interactions through pharmacokinetic mechanism [2].…”

Section: Discussionmentioning

confidence: 97%

Significant Drug Interactions Among Intensive Care Unit Patients

Hamidy

Fauzia

2017

Asian J Pharm Clin Res

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Objective: Drug interaction is one factor that contributes to drug-related problems. The hospitalized patients in intensive care units (ICU) have a higher risk for developing drug interactions. The purpose of this study was to evaluate the potency of significant drug interactions in ICU patients.Methods: Drug-drug interactions from patient's medical records from ICU of Arifin Achmad General Hospital in Pekanbaru, Province of Riau, Indonesia at period of July to December 2015 were assessed. Drug Interaction Checker (Medscape) software was used to identify potential drug interactions.Results: This study included 28 ICU patients (mean age, 48 years) who had the potency to drug interactions based on the software. Of these, 29% were male and 71% were female patients. The number of drugs that were given to patients was 3-13 drugs (average 7 drugs per patient). There were 122 potential drug-drug interactions found in this study, including 43% potency of minor or non-significant, 52% potency of significant, 3% potency of serious, and 2% potency of contraindicated drug interactions. A total of 67% were pharmacodynamics and 33% were pharmacokinetics interactions. Dexamethasone, ketoprofen, ketorolac, furosemide, nifedipine, and enoxaparin were among drugs with the highest frequency of potential drug interactions. Conclusion:Significant drug-drug interactions were prevalent in the ICU patients. This may be due to the complexity of the pharmacotherapies administered. The health professionals who provide care to these patients should be aware to identify and prevent possible drug events.

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“…Although this is not exceptionally high (Bregnhøj reported prescribing of ineffective medication in 6% of all GP prescriptions 5 ), AVDs may cause serious side effects, like dystonia and parkinsonism. 6,7 Next to this, prescribing ineffective drugs may distract from the preferred approach of non-vestibular dizziness in older patients: a systematic exploration of possible contributory causes of dizziness that are amenable to treatment.…”

Section: Looks Vestibular: Irrational Prescribing Of Antivertiginous mentioning

confidence: 99%

Looks vestibular: irrational prescribing of antivertiginous drugs for older dizzy patients in general practice

Maarsingh¹,

Schellevis²,

Horst³

2012

Br J Gen Pract

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Prevalence of inappropriate prescribing in primary care

Cited by 58 publications

References 27 publications

Evaluation Of Pharmacotherapy Used On Geriatric Population In An Institution Of Special Regime With The Screening Tool Of Older Persons’ Potentially Inappropriate Prescriptions (STOPP) Criteria

Evaluation Of Pharmacotherapy Used On Geriatric Population In An Institution Of Special Regime With The Screening Tool Of Older Persons’ Potentially Inappropriate Prescriptions (STOPP) Criteria

Significant Drug Interactions Among Intensive Care Unit Patients

Looks vestibular: irrational prescribing of antivertiginous drugs for older dizzy patients in general practice

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