Prevalence of lipid abnormalities in Poland. The NATPOL 2011 survey

Abstract

A b s t r a c tBackground: Poland represents a country of high cardiovascular (CV) risk. The association between lipid abnormalities and increased CV risk is well established. Therefore, it is important to monitor the prevalence and control of dyslipidaemia. Aim:To evaluate serum lipids concentrations as well as the prevalence, awareness, and control of lipid abnormalities in a representative sample of adults in Poland. Methods:In 2011, in a national cross-sectional survey blood samples were collected from 1168 males and 1245 females, aged 18-79 years, for measurement of total cholesterol (TC), high density lipoprotein cholesterol (HDL-C), and triglycerides (TG) in blood serum. Low density lipoprotein cholesterol (LDL-C) was calculated using Friedewald's formula.Results: Mean serum TC concentration was 197.1 mg/dL in males (M) and 198.6 mg/dL (95% CI 195.7-201.5) in females (F). Levels of LDL-C were 123.6 mg/dL (120.9-126.2) and 123.7 mg/dL (121.4-126.1), HDL-C -45.8 mg/dL (44.7-47.0) and 54.1 mg/dL (53.1-55.1), TG -140.9 mg/dL (133.0-148.8) and 104.0 mg/dL (99.8-108.2) for males and females, respectively. TC ≥ 190 mg/dL was found in 54.3% subjects (M 54.3%; F 54.4%). After adding patients on lipid-lowering treatment, hypercholesterolaemia was present in 61.1% of adults (M 60.8%; F 61.3%). LDL-C ≥ 115 mg/dL was detected in 57.8% of all subjects (M 58.3%; F 57.3%), while HDL-C < 40 mg/dL in 35.2% of males and < 45 mg/dL in 22% of females TG ≥ 150 mg/dL was found in 21.1% of subjects (M 28.4%; F 14.0%). The highest prevalence of elevated TC and LDL-C levels was present in the age group of 40-59-year-olds. Of those with hypercholesterolaemia 58.7% (M 61.5%, F 56.0%) were not aware of the condition; 22.0% (M 21.0%, F 24.5%) were aware but were not being treated; 8.1% (M 7.7%, F 8.5%) were treated but with TC ≥ 190 mg/dL; and only 10.9% (M 10.7%, F 11.0%) were being treated with TC < 190 mg/dL. Conclusions:The prevalence of dyslipidaemia in Poland continues to be high -over 60% of adults have hypercholesterolaemia, and control remains poor. The results of the NATPOL 2011 survey call for urgent preventive measures.

Risk factors, prognosis, and secondary prevention of myocardial infarction in young adults in Poland

“…The most intimidating fact is that 58.7% of all patients were unaware of their high cholesterol level. Additionally, only 10.9% of patients were treated successfully [27].…”

“…The results of NATPOL 2011 [27] assess the prevalence of hypercholesterolaemia in the Polish population at 62%. The prevalence of hypercholesterolaemia varied with sex and age.…”

Czynniki ryzyka sercowo-naczyniowego w grupie 100 pacjentów z zatorem tętnic siatkówki — rejestr jednoośrodkowy

“…The prevalence of hypertension in our patients with RAO was much higher compared to the general Polish population evaluated in the NATPOL 2011 study (78 vs. 31.9%) [13]. Regarding lipid parameters, our patients with RAO had more hypercholesterolemia (67% vs. 61.1%) and higher total cholesterol, LDL cholesterol, and TG levels compared to the NATPOL 2011 study population (205 vs. 198 mg/dL, 126 vs. 123 mg/dL, and 147 vs. 122 mg/dL, respectively) while the mean HDL cholesterol in patients with RAO was lower (47 vs. 50 mg/dL) [14]. In a similar WOBASZ II study in the Polish population, the rate of hypercholesterolemia was 67%, close to our findings [15].…”

Dyslipidemia aterogenna w codziennej praktyce — interdyscyplinarny konsensus polskich ekspertów

“…Hipertriglicerydemia (TG ≥ 150 mg/dl) występuje u 22% badanych (u 28% mężczyzn i u 14% kobiet). Jeżeli za próg hipertriglicerydemii przyjąć TG wynoszące co najmniej 200 mg/dl, dotyczy ona blisko 11% dorosłych Polaków [4]. Wspominane dane z badania NATPOL 2011 pozwalają szacować, że 10,5 miliona dorosłych Polaków na obniżone stężenie HDL-cholesterolu, a 3,2 mln na stę-żenie TG wynoszące 200 mg/dl lub wyższe.…”