Prevalence of lower urinary tract infection in South Indian type 2 diabetic subjects

Abstract

This study was done to determine the prevalence of lower urinary tract infection (UTI), the causative pathogens, their antimicrobial pattern, and the recurrence of infection in type 2 diabetic subjects. A total of 1157 (M: F 428: 729) type 2 diabetic subjects were selected for this study. Midstream urine specimens were collected and the culture tests were done by a quantitative method whereas antimicrobial sensitivity was determined by using the Kirby-Bauer method. A significant colony count was seen in 495 (42.8%) subjects and an insignificant count in 350 (30.3%) subjects; there were a few cases of recurrent UTI. Women (47.9%) had a significantly higher prevalence of UTI than men (34.1%) (χ2 = 20.3, P < 0.0001). Except for BMI, UTI was significantly associated with age, duration of diabetes, and poor glycemic control in both sexes. About 533 pathogens of gram positive and gram negative bacilli were isolated from 495 subjects in this study. Escherichea coli (E. coli) was the most commonly found organism. Gram negative pathogens were found to be highly sensitive to sulbactum / cefoperazone and piperacillin / tazobactum. The prevalence of UTI was significantly higher in women than men with E. coli being the major isolated pathogen. Gram negative pathogens were highly sensitive to sulbactum / cefoperazone and piperacillin / tazobactum.

Morbidity Profile and Causes of Mortality in Type 2 Diabetes Patients: Data from a Tertiary Teaching Hospital from Eastern India

“…Sridhar CB et al reported symptomatic UTI to be 14% in mostly menopausal women with DM, which is significantly lower than our observation, which may be due to the fact that our study is hospital based and most of the hospital admissions are due to infections that encompass UTI mostly [33]. Our observation is comparable with that of Bettegowda S et al who reported prevalence of UTI to be 26.8% and E. coli was the most common pathogen isolated followed by Candida albicans and Jenifer J et al from South India who reported prevalence of UTI to be 42.8% and E. coli as the most common pathogen isolated where as sterile culture was found in 24.3% cases [34] [35].…”

“…11.6% [33] and 4.4% [34] possibly because of a referral tertiary care hospital and emphasizes the importance of non-tubercular pulmonary infection in subjects with T2DM. Tuberculosis (TB) was found in 4.5% cases in our series.…”

Urinary tract infections in Romanian patients with diabetes: prevalence, etiology, and risk factors

“…Various studies have estimated the prevalence of UTIs among patients with DM, obtaining similar results in the United States 5,11. In developing countries, the prevalence of UTIs is significantly higher: in Saudi patients with DM, Al-Rubeaan et al obtained a prevalence of UTIs of 25.3%,12 higher in females (41.1%) than in males (7.2%) and similar in both types of DM, while in India, the reported prevalences of UTIs in patients with DM ranged between 42% and 45% 13,14. The variation in the reported rates of UTIs by geography may be due to cultural differences.…”

Asymptomatic Bacteriuria Among Type 2 Diabetes Mellitus Patients in Primary Care Centre in Saudi Arabia.

“…The microorganisms causing ASB in persons with diabetes mellitus are similar to those causing bacteriuria in non-diabetic individuals 16,20,24 . In most previous studies, E coli was the most prevalent microorganism (59.1%) recovered from the urine cultures of the participants with high sensitivity to nitrofurantoin.…”