Prevalence of obesity in type 2 diabetes in secondary care: association with cardiovascular risk factors

Daousi, Christina; Casson, Ian; Gill, Geoff; MacFarlane, I A; Wilding, John; Pinkney, Jonathan

doi:10.1136/pmj.2005.039032

Cited by 272 publications

(211 citation statements)

References 27 publications

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“…HbA1c level increased with BMI in our study but it was poorly correlated with BMI in the JDCS. Other studies have reported that diabetic patients with obesity had poor control of blood glucose, blood pressure and serum lipids, although they were more likely to be receiving antihypertensive drugs and lipidlowering drugs compared with non-obese patients [4,5]. In our study, patients in the older age group had glycemic, blood pressure and serum lipid control that was almost acceptable, even in those with BMI ≥30.…”

Section: Discussionsupporting

confidence: 52%

Twelve-year trends of increasing overweight and obesity in patients with diabetes: the Shiga Diabetes Clinical Survey

et al. 2018

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Abstract. The prevalence of obesity is increasing globally in patients with diabetes. This study aimed to examine 12-year trends of increasing obesity in Japanese patients with diabetes, and their clinical features. The study used results of the Shiga Diabetes Clinical Survey, which recorded medical performance in diabetic patients in 2000, 2006 and 2012. Data were analyzed from 14,205, 14,407 and 21,449 adult patients in these three years, respectively. Overweight and obesity prevalence and the clinical features of diabetes patients were examined, stratified by body mass index (BMI) and age. The prevalence of overweight (BMI 25-30 kg/m 2 ) and obesity (BMI ≥30 kg/m 2 ) were 27.0% and 5.1% in 2000, 28.9% and 7.3% in 2006 and 30.9% and 10.0% in 2012. Glycemic control, blood pressure and serum lipid profile improved over 12 years in all BMI categories. However, glycemic and triglyceride control were insufficient in obese patients aged <65 years (hemoglobin A1c 7.5 ± 1.4%, triglyceride 197.7 ± 178.4 mg/dL in 2012). The percentage of patients who used antihypertensive and lipidlowering drugs increased and patients with higher BMI had increased frequency of using these drugs, both in young and old age groups. Higher BMI was significantly and positively associated with albuminuria. In summary, overweight and obesity have increased in Japanese diabetic patients, particularly for younger generations. Findings suggest that obesity may lead to poorer glycemic control, blood pressure and lipid profiles. Overweight and obesity are important modifiable risk factors for diabetes, suggesting that more active weight-control interventions are warranted.

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Section: Discussionsupporting

confidence: 52%

Twelve-year trends of increasing overweight and obesity in patients with diabetes: the Shiga Diabetes Clinical Survey

et al. 2018

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“…This is lower than the findings of Daousi et al (2006) which showed that 86% of the studied subjects were obese. It is also lower than the findings of the study done in Oyo State, Nigeria by Fadupin et al (2004) where it was found that 83.0% of the out-patients were either overweight or obese.…”

Section: Discussioncontrasting

confidence: 54%

Nutritional status, lifestyle and knowledge of predisposing factors on hyperlipedemia among out-patients in Enugu State University Teaching Hospital (ESUTH), Nigeria

Nwamarah¹,

Otitoju²,

Otitoju³

2016

Afr. J. Biotechnol.

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The growing trend of hyperlipidemia in most developing countries has resulted largely from changes in lifestyle, diet and lack of adequate exercise which have led to decreased life expectancy and burden of cardiovascular diseases. A purposive sample size of 206 out-patients was selected for this study after obtaining their due consents. Out of these, 108 (52.84%) were female and 98 (47.6%) males. Validated structured questionnaires were administered to collect basic socio-economic data from the respondents. Information obtained include drinking habits, medical history, and dietary habits. Data were presented by using descriptive statistics: frequencies and percentages. The anthropometric variables (weight and height) were analysed by using mean and standard deviation tools. Body mass index (BMI) was determined using the weight and height measurements. About 39.8% of respondents were within the age bracket (29-39 years), 25.7% had family history of diabetes mellitus, 25.2% hypertension and 11.7% had hypercholesterolemia. More than half (66.5%) of the respondents consumed alcoholic drinks. About 65.1% of the alcoholics, drink 1-3 times weekly and 46.1% took alcohol 4-6 times weekly while 14.5% drink daily. Some respondents who consumed groundnut, banana with groundnut, biscuit, buns, bread, meat pies, cakes or chicken pies with malt, juice or soft drink were 63.5%. Less than half (40.2%) of the respondents were overweight and about 37.4% of them were obese. About 45.6% of the respondents had a fair knowledge of hyperlipidemia, 40.3% had poor knowledge while 14.1% had a good knowledge. This study showed a strong evidence of poor knowledge of hyperlipidemia among out-patients attending Enugu State University Teaching Hospital (ESUTH), which may have influenced their lifestyle, dietary habit and subsequently their nutritional/health status.

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“…Recent cross-sectional data revealed that 37% of 44 042 Swedish patients with type 2 diabetes had BMI X30 kg/m 2 ). 10 Other recent analyses have identified 75% of Brazilian type 2 diabetes patients as overweight (BMI425 kg/m 2 ) and 30% as obese, 11 while in the United Kingdom 12 and United States, 13 85 and 86%, respectively, were overweight and 52 and 55%, respectively, were obese. The prevalence of both obesity and diabetes is increasing rapidly.…”

Section: Role Of Obesity In the Pathogenesis And Management Of Typementioning

confidence: 99%

Metformin and body weight

2007

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Most patients with type 2 diabetes are overweight or obese, overweight or obesity increases the risk of developing type 2 diabetes and obesity per se is strongly associated with multiple cardiometabolic risk factors. However, many antidiabetic treatments increase body weight. The oral antidiabetic agent, metformin, has been evaluated in hundreds of clinical studies in diverse patient populations during approximately five decades of clinical use. This review summarizes the effects of metformin on body weight, with special reference to studies of longer duration (X6 months) as both diabetes and obesity are long-term conditions. Approximately half of studies in drug-naive type 2 diabetic patients demonstrated significant weight loss with metformin compared with baseline or comparator drugs, although pooled analyses have suggested no significant effect versus placebo. Similarly, metformin has been shown to induce weight loss in obese nondiabetic populations, although studies of long duration in this population are scarce. Metformin does appear to mitigate the adverse effects of insulin on body weight. The weight-neutral or weight-sparing effects of metformin constitute a therapeutic advantage in diabetes management where other first-line oral antidiabetic treatments often promote clinically significant weight gain.

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Prevalence of obesity in type 2 diabetes in secondary care: association with cardiovascular risk factors

Cited by 272 publications

References 27 publications

Twelve-year trends of increasing overweight and obesity in patients with diabetes: the Shiga Diabetes Clinical Survey

Twelve-year trends of increasing overweight and obesity in patients with diabetes: the Shiga Diabetes Clinical Survey

Nutritional status, lifestyle and knowledge of predisposing factors on hyperlipedemia among out-patients in Enugu State University Teaching Hospital (ESUTH), Nigeria

Metformin and body weight

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