Prevalence of organic colonic lesions in patients meeting Rome III criteria for diagnosis of IBS: a prospective multi-center study utilizing colonoscopy

Abstract

The prevalence of organic colonic diseases in patients who met the Rome III criteria was at an acceptably low level, indicating that the Rome III criteria are adequately specific for the diagnosis of IBS without performing a colonoscopy examination.

Prevalence of irritable bowel syndrome-like symptoms in ulcerative colitis patients with clinical and endoscopic evidence of remission: prospective multicenter study

“…To confirm the relationship of endoscopic findings with the presence of IBS-like symptoms in UC patients, it is important to analyze a large number of subjects who underwent a colonoscopy. In addition, the prevalence rate of IBS found in the control group was relatively low (4.8%), which was similar to the result of our recent study regarding the prevalence of IBS in Japanese subjects (4.4%) [2]. Epidemiological studies using a validated symptom-based definition, such as that by Manning, or Rome criteria have demonstrated various prevalence rates of IBS ranging from 2.5% to 25% in general populations [4].…”

“…The Japanese version of the questionnaire used in this study was validated in our previous study [2].…”

“…Irritable bowel syndrome (IBS) is a chronic functional disorder of the intestinal tract in the absence of organic abnormalities and characterized by clinical symptoms such as abdominal pain and discomfort, along with alterations in bowel habits [1][2][3][4][5]. IBS represents a highly prevalent intestinal disease that affects around 10-15% of adults in most countries, and a number of studies have demonstrated that psychological distress, disturbances of intestinal motility and visceral hypersensitivity are closely associated with its pathogenesis [6][7][8].…”

Overlapping of Organic Disorders with Irritable Bowel Syndrome Among Teachers in Tabuk, Saudi Arabia Using Rome III Criteria

“…The marital status was not significant in the current study in accordance with previous research [17] The rate of an organic lesion on colonoscopy among patients with irritable bowel syndrome and no red flag signs was not higher as compared to healthy controls ranging from 10-40% [19,20]. By contrast: during the year following the diagnosis of irritable bowel syndrome the diagnosis of inflammatory bowel diseases was 9-16 times higher [21][22][23][24].…”

What is irritable bowel syndrome?

“…In this classic form, and in the absence of alarm features, the diagnosis is usually obvious to the experienced functional gastroenterologist familiar with the nonverbal clues that can help to substantiate the clinical impression. With this positive approach to diagnosis, investigation should be aimed at excluding realistic alternatives rather than being exhaustive and there is evidence to suggest that significant disease is seldom missed by following such a course of action [Vanner et al 1999;Jellema et al 2009;Ishihara et al 2012]. However, very reasonably, others feel extremely uncomfortable with this symptom-based style of diagnosis and think that a more scientific, pathophysiology-based approach should be developed.…”