2018
DOI: 10.3399/bjgp18x694589
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Prevalence of primary aldosteronism in primary care: a cross-sectional study

Abstract: In this study a prevalence of PA of 2.6% in a primary care setting was established, which is lower than estimates reported from other primary care studies so far. This study supports the screening strategy as recommended by the Endocrine Society Clinical Practice Guideline. The low proportion of screened patients (9.2%), of the large cohort of eligible patients, reflects the difficulty of conducting prevalence studies in primary care clinical practice.

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Cited by 47 publications
(36 citation statements)
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“…In contrast, according to a retrospective, international, multicenter study by Mulatero et al published in 2004, hypokalemic PA in fact accounts for only 9-37 % of cases [15]. This number is consistent with the results of numerous other studies [64][65][66][67][68]. ▶table 2 gives an overview of the relevant results of cited studies.…”
Section: Prevalence Of Hypokalemia In Pasupporting
confidence: 66%
“…In contrast, according to a retrospective, international, multicenter study by Mulatero et al published in 2004, hypokalemic PA in fact accounts for only 9-37 % of cases [15]. This number is consistent with the results of numerous other studies [64][65][66][67][68]. ▶table 2 gives an overview of the relevant results of cited studies.…”
Section: Prevalence Of Hypokalemia In Pasupporting
confidence: 66%
“…Furthermore, the included subjects had only mild hypertension most likely due to diagnosis at earlier stages of the disease resulting from an increasing awareness for primary aldosteronism and broadened indications for screening. Therefore, the study population might not represent the historically described population with primary aldosteronism which presented most often with moderate to severe hypertension (30,31).…”
Section: Discussionmentioning
confidence: 99%
“…Primary aldosteronism (PA) is one of the most common causes of secondary hypertension. The estimated prevalence ranges from 3-6% in primary care [1,2] to 5-11% in referred hypertensive patients [3,4] and is even higher in patients with resistant hypertension (more than 11%) [5]. Diagnosing PA is important as targeted therapy may lower the increased risk for cardiovascular events and target organ damage [6] in these patients.…”
Section: Introductionmentioning
confidence: 99%