Prevalence of Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma in Upper Egypt

Shazly, Tarek A.; Farrag, Abdelsattar; Kamel, Asmaa A.; Al-Hussaini, Ashraf K.

doi:10.1186/1471-2415-11-18

Cited by 41 publications

(26 citation statements)

References 28 publications

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“…The high frequency of glaucoma in this hospital-based study may be due to the regular follow-ups attended by glaucoma patients. Similarly a high frequency of glaucoma has been found in hospital-based studies with reported rates of 33.1% by Al-Bdour et al [17], 30.3% by Shazly et al [23], and 40% by Rao et al [24]. Kaljurand and Teesalu [25] reported a high frequency of 35.7% for glaucoma in their population-based study although the glaucoma frequency is generally lower in population-based studies [4, 26, 27].…”

Section: Discussionsupporting

confidence: 57%

The Frequency of Exfoliation Syndrome in the Central Anatolia Region of Turkey

Kılıç

Sezer

Çomçalı

et al. 2014

Journal of Ophthalmology

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Aim. The aim of this study was to investigate the frequency of exfoliation syndrome in the Central Anatolia region of Turkey and to evaluate its relationship with cardiovascular and ocular diseases. Methods. Patients over the age of 45 years who presented to the clinic were included in the study. All cases underwent a comprehensive ophthalmology examination. Exfoliation syndrome was diagnosed with the presence of exfoliative material on the lens anterior capsule or iris on slit lamp examination. The patients were divided into two groups as the exfoliation syndrome group and nonexfoliation syndrome group according to the presence of exfoliative material. Results. Exfoliative material was found in one or both eyes of 212 of the 2103 patients (10.1%) evaluated within the scope of the study. A significant relationship was found between exfoliation syndrome and increasing age and male gender. A significant relationship was found between exfoliation syndrome and glaucoma, cataracts, age-related macular degeneration, and phacodonesis. While no relationship was found between exfoliation syndrome and hypertension or diabetes mellitus, a significant relationship was found with coronary artery disease. Conclusion. The unilateral or bilateral exfoliation syndrome frequency was 10.1% in this hospital-based study. A statistically significant relationship was found between exfoliation syndrome and advancing age, gender, and coronary artery disease.

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Section: Discussionsupporting

confidence: 57%

The Frequency of Exfoliation Syndrome in the Central Anatolia Region of Turkey

Kılıç

Sezer

Çomçalı

et al. 2014

Journal of Ophthalmology

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“…However, a hospital-based study in Saudi Arabia and Pakistan found 45% and 40% of patients with PXS to have high IOP [6,9]. Also the prevalence of elevated IOP associated with exfoliation syndrome in this study was lower than has been reported by Al Jaffal Z and Kayyali in Syria (37.5%) [10], Al-Bdour et al in Jordan (33.1%), [11] Shazly et al in Egypt (30.4%) [12] and Yalaz et al in Turkey (32.1%) [13]. In India, 34% of exfoliation syndrome patients have "manifest glaucoma," although the criteria for the diagnosis of glaucoma are not detailed [14].…”

Section: Discussioncontrasting

confidence: 64%

The Prevalence of Glaucoma among Pseudoexfoliation Syndrome Patients

Al-Saffar¹,

Ahmed²

2019

SJMPS

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Introduction: Pseudoexfoliation syndrome is a recognized risk factor for developing glaucoma, cataract and lens dislocation. Pseudoexfoliation syndrome is also associated with increased risk of complications during cataract surgery due to poor mydriasis and zonular weakness. Objective: The aim is to find out the prevalence of glaucoma in Pseudoexfoliation syndrome patients attended to Shaheed Doctor Aso hospital, Sulaimaniya city, Kurdistan region of Iraq and Azadi Teaching Hospital, Kirkuk city-Iraq. Patients and Methods: This cross sectional study encompassed 378 patients (756 eyes) with whom the pseudoexfoliation syndrome was detected as an incidental finding aged 50 years or older. A detailed evaluation including general and ophthalmic history, slit lamp biomicroscopy, intraocular pressure measurement (TOPCON computerized tonometer CT-80 and Goldmann Applanation tonometer), gonioscopy (Goldmann three mirrors goniolens) and dilated eye examination were performed. Oral informed consent was obtained from all participants. Results: Out of the 378 patients who had pseudoexfoliation syndrome, 58 (15.3%) were diagnosed with pseudoexfoliation glaucoma and 34 patients (9%) with ocular hypertension. In the glaucomatous patients, men to women ratio was 2:1, this was statistically significant (p = 0.001). Most of patients in the age group (70-79) years of age, represent 23.3%. Bilateral Pseudoexfoliation syndrome was associated more with pseudoexfoliation glaucoma (58.6%), while unilateral pseudoexfoliation syndrome was associated more with ocular hypertension (64.7%). The Kurdish race patients expressed the highest prevalence of pseudoexfoliation glaucoma and ocular hypertension (31.5%) followed by the Arabic race (20%) and lastly the Turkmen (16%). Conclusion: Pseudoexfoliation syndrome showed to be a significant glaucoma risk factor locally, with a prevalence of (15.3%), and if we added the Ocular hypertension (9%), it will be (24.3%). Recommendation: Patients with Pseudoexfoliation syndrome should be informed and examined at least annually as the risk may be present throughout their life and increasing with age.

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“…The prevalence of PXS in Nigerian communities has been reported to be very low [16]. However; several investigators have reported high proportions of PXG among patients with PXS, ranging from 30.3% [17] to 67% [16].…”

Section: Introductionmentioning

confidence: 99%

Prevalence and Associations of Pseudoexfoliation Glaucoma in a Group of Tertiary Eye Care Facilities in Southwest Nigeria

Onochie¹,

Okoye²,

Onakoya³

et al. 2016

OJOph

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Background: Globally, glaucoma is the leading cause of irreversible blindness. Pseudoexfoliation glaucoma is the most common form of secondary open angle glaucoma. Purpose: To determine the prevalence and characteristics of pseudoexfoliation glaucoma (PXG) among newly diagnosed glaucoma patients in Eye Foundation Hospital Ikeja, Guinness Eye Center, Lagos University Teaching Hospital and Deseret Community Vision Institute, Ijebu Imushin. Methods: This hospital-based, descriptive cross-sectional study included newly diagnosed adult glaucoma patients at the glaucoma clinics of three tertiary eye care centers. A study proforma was used to obtain socio-demographic information, medical history, ocular history and relevant findings on ocular and systemic examination. Descriptive and comparative statistical analyses were performed. Values were considered statistically significant where P < 0.05. Results: One hundred and forty adult glaucoma patients aged 60.5 ± 11.9 SD years and male to female ratio of 2:1 were examined. The prevalence of PXG among the glaucoma patients was 16.9%. The pseudoexfoliative material (PXM) was most commonly found on the pupil (39%). Common ocular features seen among PXG patients were poor pupillary dilation with mydriatic agents (44%) and Sampaolesi's line in the anterior chamber angle (41%). A higher proportion of PXG patients than primary open angle glaucoma (POAG) patients showed signs of severe glaucoma, including severe optic disc cupping (P = 0.019) and visual field defects (P = 0.014). Hearing defects were the only significantly associated non-ocular feature * Corresponding author. C. Onochie et al. 71 (P = 0.0005). Conclusion: The prevalence of PXG was 16.9%. This implies that it is relatively common in Nigeria. Hearing loss is an important non-ocular association. Careful ocular examination of glaucoma patients is recommended to identify PXG, which runs a more severe clinical course than POAG.

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Prevalence of Pseudoexfoliation Syndrome and Pseudoexfoliation Glaucoma in Upper Egypt

Cited by 41 publications

References 28 publications

The Frequency of Exfoliation Syndrome in the Central Anatolia Region of Turkey

The Frequency of Exfoliation Syndrome in the Central Anatolia Region of Turkey

The Prevalence of Glaucoma among Pseudoexfoliation Syndrome Patients

Prevalence and Associations of Pseudoexfoliation Glaucoma in a Group of Tertiary Eye Care Facilities in Southwest Nigeria

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