Prevalence of pyoderma gangrenosum and Sweet�s syndrome in inflammatory bowel disease at a tertiary healthcare center.

Giraudo, Florencia; Miraglia, E; Yantorno, Martín; Garbi, María Laura; Maradeo, María Roxana; Baldoni, Fernando; Tufare, Francisco; Correa, Gustavo Javier

doi:10.17235/reed.2020.7431/2020

Cited by 4 publications

(1 citation statement)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In an Argentinian study of 444 IBD patients, the incidence of SS was observed to be 0.7%, approximately half that of PG. In all cases of SS, corticosteroids induced complete lesion involution [148].…”

Section: Ss Has Been Noted As An Extraintestinal Manifestation Of Inf...mentioning

confidence: 92%

New Practical Aspects of Sweet Syndrome

et al. 2022

View full text Add to dashboard Cite

Sweet syndrome (SS), or acute febrile neutrophilic dermatosis, is an inflammatory, non-infectious skin reaction characterized clinically by tender, erythematous papules/plaques/pustules/nodules commonly appearing on the upper limbs, trunk, and head and neck; histologically, SS is characterized by dense neutrophilic infiltrate in the dermis. SS is accompanied by fever; an elevation of inflammatory markers (e.g., erythrocyte sedimentation rate, C reactive protein) in serum may also be observed. Although most cases of SS are idiopathic, SS also occurs in the setting of malignancy or following administration of an associated drug. SS has also been reported in association with pregnancy and a burgeoning list of infectious (most commonly upper respiratory tract infections) and inflammatory diseases; likewise, the litany of possible iatrogenic triggers has also grown. Over the past several years, a wider spectrum of SS presentation has been realized, with several reports highlighting novel clinical and histological variants. Corticosteroids continue to be efficacious first-line therapy for the majority of patients with SS, although novel steroid-sparing agents have been recently added to the therapeutic armamentarium against refractory SS. New mechanisms of SS induction have also been recognized, although the precise etiology of SS still remains elusive. Here, we catalogue the various clinical and histological presentations of SS, summarize recently reported disease associations and iatrogenic triggers, and review treatment options. We also attempt to frame the findings of this review in the context of established and emerging paradigms of SS pathogenesis.

show abstract

Section: Ss Has Been Noted As An Extraintestinal Manifestation Of Inf...mentioning

confidence: 92%