Abstract:There were significant differences in detecting asymptomatic RHD in school pupils of different countries and in different communities within a country in sub-Saharan Africa. The variation in the prevalence of RHD between countries and communities has important implications for the modelling of the global burden of RHD.
“…(17) Our results (4.9/1 000), in an older age group cohort, however corresponds with the definitive RHD rate mentioned in the Engel study (2.3/1 000 in Bonteheuwel and 6.9/1 000 in Langa). As previously mentioned, the highly variable findings in the older age groups of the Engel study makes inter-study age group comparisons difficult.…”
Section: Resultscontrasting
confidence: 43%
“…(17) The study found a prevalence rate of 30.5/1 000 in Jimma and 20.2/1 000 in Cape Town. Two populations were studied in Cape Town.…”
“…(17) Our results (4.9/1 000), in an older age group cohort, however corresponds with the definitive RHD rate mentioned in the Engel study (2.3/1 000 in Bonteheuwel and 6.9/1 000 in Langa). As previously mentioned, the highly variable findings in the older age groups of the Engel study makes inter-study age group comparisons difficult.…”
Section: Resultscontrasting
confidence: 43%
“…(17) The study found a prevalence rate of 30.5/1 000 in Jimma and 20.2/1 000 in Cape Town. Two populations were studied in Cape Town.…”
“…This strategy relies entirely on case detection and echocardiography has been identified as a superior modality (compared to clinical screening with auscultation) to deliver these cases. (5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15) However, this strategy has its problems. This focused review will critically evaluate the shortcomings of the current criteria used for the screening of asymptomatic RHD.…”
SCREENING FOR RHEUMATIC HEART DISEASEThe burden of rheumatic heart disease (RHD) remains unacceptably high in the third world, including Sub-Saharan Africa.
“…[2] In Mozambique and South Africa, RHD is estimated to affect 20 -30/1 000 asymptomatic schoolchildren. [3,4] Intramuscular penicillin is more effective than oral penicillin in the secondary preven tion of acute rheumatic fever (ARF), and is highly effective for the primary prevention of ARF in children and young adults with pharyngitis. [5,6] Intramuscular benzathine penicillin G (BPG) is therefore a first-line drug for primary and secondary prevention of ARF and RHD.…”
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