Prevalence of Salmonella serotypes and antibiogram of Salmonella typhi in a Tertiary Care Hospital in NCR Region, India

Girotra, Ruchi; Dawar, Reetika; Naz, Ruby; Garg, Sunil; Gupta, Rakesh

doi:10.20546/ijcmas.2016.504.092

Cited by 2 publications

(2 citation statements)

References 16 publications

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“…aureus at 48 h incubation. Thus, mixed results were obtained when the issues of growth inhibitory activities of honeys, against grampositive and gram-negative bacteria, have been considered; such variation in the honeys antibacterial activities has been linked to multiple issues: source and chemistry of honey, and geographic and seasonal (spatial and temporal) variation in honey collection [19,21,34].…”

Section: Discussionmentioning

confidence: 99%

Exploration of Antibacterial and Antioxidative Property of Two Natural Honey Samples from Malda District, India

Mandal¹,

Roy²,

Mandal³

2016

Transl Med (sunnyvale)

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Aims: The current study determines the antibacterial activity of 'Bakul' (Mimusops elengi) leaf, seed and bark extracts against gram-negative clinical bacterial isolates as well as the standard bacterial strains. Methods: The disc diffusion method was followed to determine the antibacterial activity of M. elengi leaf, seed and bark extracts against the clinical isolates of Escherichia coli, Klebsiella pneumoniae, Proteus vulgaris and Pseudomonas aeruginosa. The antibiotic susceptibility of the bacterial isolates was determined by disc diffusion. Results: The concentration dependent activity of the extracts against the bacteria was recorded with zone diameter of inhibition 7-21 mm. The extracts in combination with antibiotics (cefpodoxime, gentamycin and ciprofloxacin) had growth inhibitory indices (GIIs), 0.5-0.6, 0.5-0.89 and 0.73-0.82 against E. coli, K. pneumoniae and Pr. vulgaris clinical isolates, respectively, while for the standard strains (E. coli, K. pneumoniae and Ps. aeruginosa) the GIIs ranged 0.56-0.86. Most of the extracts were tested positive for the presence of flavonoids, glycosides, steroids, terpenoids, quinone and phenol. Conclusion: The M. elengi leaf, seed and bark extracts, in combination with antibiotics, had synergistic interactions against all the standard bacterial strains and Pr. vulgaris clinical isolate, while both synergistic and additive interactions were recorded against E. coli and K. pneumoniae clinical isolates.

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Section: Discussionmentioning

confidence: 99%

Exploration of Antibacterial and Antioxidative Property of Two Natural Honey Samples from Malda District, India

Mandal¹,

Roy²,

Mandal³

2016

Transl Med (sunnyvale)

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“…This discrepancy in the antibacterial potency against selected pathogens could be ascribed to the chemistry of honey (its acidic pH 3.2-4.5, high osmolarity, hydrogen peroxide, non-peroxide factors), its phytochemical nature (content of phenols, tetracycline derivatives, amylase, streptomycin, sulfathiazole, fatty acids, ascorbic acid, flavonoides, trepens, benzyl alcohol and benzoic acids, etc. ), and geographic and seasonal (spatial and temporal) variation in honey collection (Mohapatra et al 2011;Tada et al 2012;Radhakrishnan et al 2014;Girotra et al 2016;Roy et al 2016). Further, there may exist a correlation between the microbial diversity and antibacterial potential of the hive bee's honey.…”

Section: Discussionmentioning

confidence: 99%

Antibacterial potential of hive bees honey from Himachal Pradesh, India

et al. 2021

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This paper presents a pioneer study on the microbial diversity and antibacterial potential of hive bees (Apis cerana and A. mellifera) honey collected from Himachal Pradesh. In total, 26 bacteria (14 from A. cerana and 12 from A. mellifera) but no fungal isolate were recovered. Bee species and locations comparison in terms of bacterial load (log CFU/g) revealed maximum loads of 3.74 and 3.99 in the honey from A. cerana and Mandi location, respectively. The most prevalent strains (HC3, HC5, HC6, HC8 and HM2) were identified (16S rRNA ribotyping) as Staphylococcus haemolyticus (MT742636), "Bacillus subtilis subsp. stecoris" (MT742637), Bacillus safensis subsp. safensis (MT742638), "Bacillus zanthoxyli" (MT742639) and Bacillus safensis subsp. safensis (MT938911). The apiary honey displayed good to excellent inhibitory activity against Escherichia coli ATCC1041 whereas, fair to good against Bacillus subtilis ATCC6633, Pseudomonas aeruginosa ATCC10662, Salmonella typhi NCTC786 and Klebsiella pneumoniae ATCC13883, highlighting its use as a therapeutic agent. Furthermore, it can be effective in minimizing numerous side effects associated with the consumption of synthetic drugs for treating bacterial infections thereby signifying the role of honey as a healthier substitute for synthetic drugs.

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Prevalence of Salmonella serotypes and antibiogram of Salmonella typhi in a Tertiary Care Hospital in NCR Region, India

Cited by 2 publications

References 16 publications

Exploration of Antibacterial and Antioxidative Property of Two Natural Honey Samples from Malda District, India

Exploration of Antibacterial and Antioxidative Property of Two Natural Honey Samples from Malda District, India

Antibacterial potential of hive bees honey from Himachal Pradesh, India

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