Prevalence of sleep disturbances and their effects on quality of life in adults with untreated pituitary tumor and meningioma

Lin, Mei Ru; Chen, Pin Yuan; Wang, Huan-Chih; Lin, Pei; Lee, Hsin Chien; Chiu, Hsiao‐Yean

doi:10.1007/s11060-021-03811-w

Cited by 7 publications

(14 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Finally, consistent with previous literature, the results from the HRQoL studies highlighted the occurrence of sleep disturbance in a symptom cluster with other prevalent symptoms, such as fatigue, drowsiness, stress, and pain [17,18,27,45]. Two studies explored whether tumour characteristics such as location or laterality impacted sleep regulation or QoL; however, neither location and/or laterality appeared to be associated with sleep disturbance in the current review [18,21]. Only one study (n = 5) reported caregiver sleep [37], thus limiting the ability to explore risk factors or clinical associations for sleep disturbance in caregivers specifically.…”

Section: Risk Factors/clinical Associationssupporting

confidence: 83%

“…Most articles reported gender distribution, noting PBT survivors were predominantly male (52%) and caregivers female (71%). Ten studies exclusively included high-grade glioma (HGG) samples [ 17 , 24 , 25 , 30 , 36 , 37 , 40 , 43 , 46 , 47 ], while seven exclusively included low-grade glioma (LGG) samples [ 21 , 23 , 27 , 31 , 35 , 39 , 42 ]. Seventeen studies involved mixed samples of LGG and HGG [ 14 – 16 , 19 , 20 , 22 , 26 , 28 , 29 , 32 – 34 , 38 , 39 , 41 , 44 , 45 ].…”

Section: Resultsmentioning

confidence: 99%

“…Sleep was primarily assessed using validated subjective questionnaires, including the Pittsburgh Sleep Quality Index (PSQI) [ 19 , 21 , 29 , 33 , 37 ], the Insomnia Severity Index (ISI) [ 29 , 45 ], the Epworth Sleepiness Scale (ESS) [ 21 ], the Athens Insomnia Scale (AIS) [ 21 ], the General Sleep Disturbance Scale (GSDS) [ 17 ], and the Brief Sleep Disturbance Scale (BSDS) [ 32 ]. Furthermore, validated symptom or outcome measures reporting ≥ 1 sleep item included the NCCN Distress thermometer [ 20 ], the PROMIS Clinical Outcomes Assessment (V1) [ 22 ], the Fact-BR [ 36 ], and the Common Terminology Criteria for Adverse Events (CTCAE) [ 26 ].…”

Section: Resultsmentioning

confidence: 99%

“…All 34 included articles were published between 1998 and 2022, consisting of 16 cross-sectional studies [14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29], 7 randomised control trials (RCT) [30][31][32][33][34][35][36], 4 quasi-experimental studies [37][38][39][40], and 7 cohort studies [41][42][43][44][45][46][47]. The results of the included articles were informed by 4,694 PBT survivors and 120 caregivers, with sample sizes ranging from 12 to 621 with an age range of 18-86 years.…”

Section: Characteristics Of Included Studiesmentioning

confidence: 99%

“…In total, 9 (25%) included articles had a primary focus on the prevalence, severity or presentation of sleep disturbance in PBT survivors [19-22, 26, 29, 30, 38], with the remaining articles having a primary focus on HRQoL [14-18, 23-25, 28, 30-37, 39-48]. Of five studies that used the PSQI, three reported the percentage of people scoring > 5 (i.e., significant sleep disturbance) with results estimating the prevalence of sleep disturbance between 37.0 and 81.8% [19,21,29]. One study using the GSDS [17] reported 100% of subjects experienced sleep disturbance.…”

Section: Characteristics Of Included Studiesmentioning

confidence: 99%

See 4 more Smart Citations

Prevalence and management of sleep disturbance in adults with primary brain tumours and their caregivers: a systematic review

et al. 2023

View full text Add to dashboard Cite

Purpose The aims of this systematic review were to (1) examine the prevalence, severity, manifestations, and clinical associations/risk factors of sleep disturbance in primary brain tumour (PBT) survivors and their caregivers; and (2) determine whether there are any sleep-focused interventons reported in the literature pertaining to people affected by PBT. Methods This systematic review was registered with the international register for systematic reviews (PROSPERO: CRD42022299332). PubMed, EMBASE, Scopus, PsychINFO, and CINAHL were electronically searched for relevant articles reporting sleep disturbance and/or interventions for managing sleep disturbance published between September 2015 and May 2022. The search strategy included terms focusing on sleep disturbance, primary brain tumours, caregivers of PBT survivors, and interventions. Two reviewers conducted the quality appraisal (JBI Critical Appraisal Tools) independently, with results compared upon completion. Results 34 manuscripts were eligible for inclusion. Sleep disturbance was highly prevalent in PBT survivors with associations between sleep disturbance and some treatments (e.g., surgical resection, radiotherapy, corticosteroid use), as well as other prevalent symptoms (e.g., fatigue, drowsiness, stress, pain). While the current review was unable to find any sleep-targeted interventions, preliminary evidence suggests physical activity may elicit beneficial change on subjectively reported sleep disturbance in PBT survivors. Only one manuscript that discussed caregivers sleep disturbance was identified. Conclusions Sleep disturbance is a prevalent symptom experienced by PBT survivors, yet there is a distinct lack of sleep-focused interventions in this population. This includes a need for future research to include caregivers, with only one study identified. Future research exploring interventions directly focused on the management of sleep disturbance in the context of PBT is warranted.

show abstract