Prevalence of the polycystic kidney disease and renal and urinary bladder ultrasonographic abnormalities in Persian and Exotic Shorthair cats in Italy

Abstract

The ultrasonographic findings of kidneys, liver and urinary bladder of 288 Persian and 44 Exotic Shorthair clinically normal cats that underwent screening for polycystic kidney disease (PKD) between July 2003 and December 2005 were reviewed. Cats were divided into two groups, one including cats aged <9 months (group 1) and one cats aged >/=9 months (group 2). Cats were classified as PKD-positive when at least one renal cyst was found. One hundred and thirty-six cats (41.0%) had more than one cyst in at least one kidney. The prevalence of PKD was similar in both groups. Eight PKD-positive cats had cystic livers (5.9%). Other renal abnormalities included a pelvic calculus and a medullary rim sign (MRS). The difference in prevalence of an MRS in group 2 compared to group 1 and the difference between PKD-positive and -negative cats in group 2 were not significant. There was no difference in mean kidney length between PKD-positive and -negative cats in group 2. Urinary bladder anomalies were principally represented by urinary sediment, with prevalence significantly higher in group 2. No difference was detected in group 2 between PKD-positive and -negative cats. In conclusion feline PKD is common in Italy. The ultrasonographic findings of MRS and urinary bladder sediment did not correlate with feline PKD. Urinary bladder sediment is common in Persians and Exotic Shorthairs and more likely in adults.

Bilateral multiple cystic kidney disease and renal cortical abscess in a Boerboel

“…Polycystic kidney disease has been diagnosed in the Persian cat and English bull terrier, West highland white terrier and Cairn terrier dogs [4][5][6][7]12,32,33,36,37 and the cysts have been reported to originate from mainly the collecting duct and the distal part of the nephron 17 . The sensitivity and specificity for the detection of PKD in Persian cats at an age of 3 months using ultrasonography has been shown to be 92.6 % and 91 %, respectively 8 .…”

Urinary Tract

“…17,[38][39][40][41][42][43][44][45][46][47][48][49][50][51] Polycystic renal disease an autosomal dominant mutation, is the most common inherited renal disease of cats and prevalence in Persians is 37% to 49%. 17,[38][39][40][41][42][43][44][45][46][47][48][49][50][51] Polycystic renal disease an autosomal dominant mutation, is the most common inherited renal disease of cats and prevalence in Persians is 37% to 49%.…”

High Resolution Ultrasonography for Assessment of Renal Cysts in the PCK Rat Model of Autosomal Recessive Polycystic Kidney Disease

“…Furthermore, ultrasonography examination was shown to be useful and reliable for diagnosing PKD in cats with polycystic kidney [17][18][19]. It has also been shown that the resistive index which measures the arterial resistance in the peripheral vessels by Duplexultrasound is a valuable diagnostic tool to detect renal diseases in cats [20].…”