Prevalence of Thrombocytopenia during Pregnancy & Its Effect on Pregnancy & Neonatal Outcome

Abstract

Background: To study the Prevalence of thrombocytopenia during pregnancy and its effect on pregnancy and neonatal outcome. Methods: It was a prospective one year study of pregnancy with thrombocytopenia. The cause of thrombocytopenia and feto-maternal outcomes in pregnancy with thrombocytopenia was studied. Results: Among 1450 deliveries, total 137 women were having thrombocytopenia in third trimester. The commonest etiology was gestational thrombocytopenia (61%). Thrombocytopenia due to severe preeclampsia and HELLP syndrome in this study was 24%,Placental abruption 9(6.6%), PPH 6(4.3%), Wound hematoma 5(3.6%) were noted. Fetal complications -stillbirth 11(8%), low birth weight 14(10.21%), low APGAR 22(16.2%) and neonatal thrombocytopenia 6(4.3%). Thrombocytopenia in pregnancy did not affect the mode of delivery and pre-term delivery rate. Conclusion: Feto-maternal complications with thrombocytopenia depend primarily on the disease causing it. Gestational thrombocytopenia, preeclampsia, HELLP syndrome, malaria, ITP and dengue were the common causes of thrombocytopenia in pregnant. Patients with GT and ITP have better maternal and peri-natal outcomes as compared to preeclampsia and HELLP syndrome.

Prevalence of thrombocytopenia in Parturient: Experience in Tertiary Care Center

“…Many reports observed higher rates of preterm deliveries in patients with moderate to severe thrombocytopenia. 4,[6][7][8]11 Our study also had a similar finding.…”

“…Several studies reported similar incidence. [6][7][8] Presence of medical and obstetric risk factors did not have any influence on maternal and neonatal outcome in these patients. This finding is similar to Nisha et al study.…”

“…Placental abruption (7%), PPH (4.3%) and DIC (9%) were the most common maternal complications noted in our study .Cesarean Section incision site oozing and wound hematoma were not observed in our study ,as compared to M Arora study. 8 Nisha et al 2 reported 9.98% PPH in their study.…”

Pregnancy emerged thrombocytopenia: maternal and fetal outcome

“…6 cases of caesarean section wound gape where one underwent exploratory laparotomy is seen in our study. 9,11,12 The study by Pallavi et al showed 1% cases and that of Sumathy et al shows that 0.5% case of incisional site oozing. 9,11 1 case of vaginal hematoma (2.17%) is seen which is similar to study by Pallavi et al having 1 case (2.5%) of episiotomy hematoma and Arora et al reported 5 (3.6%) cases of wound hematoma.…”

Prevalence of Gestational Thrombocytopenia: A Hospital Based Study

“…In our study the prevalence was 43.7%. Prevalence of gestational thrombocytopenia was 64.2% in a study conducted by Singh Nisha et al in 2012 15 . There were 74.7% cases of mild thrombocytopenia, 17.9% of moderate and 7.4% were thrombocytopenia.…”