Background: To study the Prevalence of thrombocytopenia during pregnancy and its effect on pregnancy and neonatal outcome. Methods: It was a prospective one year study of pregnancy with thrombocytopenia. The cause of thrombocytopenia and feto-maternal outcomes in pregnancy with thrombocytopenia was studied. Results: Among 1450 deliveries, total 137 women were having thrombocytopenia in third trimester. The commonest etiology was gestational thrombocytopenia (61%). Thrombocytopenia due to severe preeclampsia and HELLP syndrome in this study was 24%,Placental abruption 9(6.6%), PPH 6(4.3%), Wound hematoma 5(3.6%) were noted. Fetal complications -stillbirth 11(8%), low birth weight 14(10.21%), low APGAR 22(16.2%) and neonatal thrombocytopenia 6(4.3%). Thrombocytopenia in pregnancy did not affect the mode of delivery and pre-term delivery rate. Conclusion: Feto-maternal complications with thrombocytopenia depend primarily on the disease causing it. Gestational thrombocytopenia, preeclampsia, HELLP syndrome, malaria, ITP and dengue were the common causes of thrombocytopenia in pregnant. Patients with GT and ITP have better maternal and peri-natal outcomes as compared to preeclampsia and HELLP syndrome.

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