Prevalence of Treatment Failure among Pulmonary Tuberculosis Patients in Federal Medical Centre, Gombe, Northeastern Nigeria

Jibrin, Yusuf Bara; Ali, Aminian; Sa'ad, Sulaiman Tanimu; Kolo, P.M.

doi:10.5402/2013/461704

Cited by 14 publications

(11 citation statements)

References 13 publications

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“…This is highly unsatisfactory as it is almost impossible to control TB if such a situation persists. A similarly high treatment failure rate was reported by Jibrin et al in the Northern part of the country [20]. Our study showed a significantly higher rate of treatment failure among the HIV-positive individuals when compared to their noninfected counterparts.…”

Section: Discussionsupporting

confidence: 87%

Epidemiological characteristics and clinical outcome of HIV-related tuberculosis in a population of TB patients in South-Western Nigeria

Olowe

Makanjuola

Adekanmi

et al. 2017

EuJMI

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Tuberculosis (TB) is the second leading cause of death from infectious disease globally with its impact more dramatic in resource limited settings. Individuals with human immunodeficiency virus (HIV) infection who also develop tuberculosis represent a significant challenge to TB control. This study was carried out to determine the prevalence of TB–HIV coinfection and pattern of infection among TB patients. We also compared treatment outcome among coinfected patients with those not coinfected.A six-year retrospective review of records of patients managed at the Tuberculosis Treatment Center of the LAUTECH Teaching Hospital, South-Western Nigeria from January 2009 to December 2014 was carried out.One hundred and five (26.3%) of the 399 TB patients seen in the study period were coinfected with HIV. About 10% of the subjects had extrapulmonary tuberculosis. Treatment failure was significantly worse among patients who had both HIV and TB compared with those who had TB only (49.5% vs. 32%, p = 0.001). Death rate was also higher in the coinfected individuals implying a poorer clinical outcome.High prevalence of TB–HIV coinfection and poor treatment outcome in this group of individuals, though predictable, calls for a more concerted effort in the management of TB–HIV coinfection.

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Section: Discussionsupporting

confidence: 87%

Epidemiological characteristics and clinical outcome of HIV-related tuberculosis in a population of TB patients in South-Western Nigeria

Olowe

Makanjuola

Adekanmi

et al. 2017

EuJMI

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“…This study showed that pulmonary tuberculosis affects mostly the most productive age group of the population unlike in developed countries where TB affects mostly the elderly (P D O Devies, 1999) which is similar with other the findings of other studies (Jibrin et al, 2013), , (Kochi 1999). These are active, skillful, experience and mobile individual that drive the economy of the developing nation (Armstrong 1995).…”

Section: Discussionsupporting

confidence: 87%

“…This will have positive effect on the compliance and reduce the chances of lost to follow-up. A similar finding was documented by (Jibrin et al, 2013). In some studies, the patients have to travel a distance of more than 7Km to the treatment centre and that implicate poor treatment outcome (Lisha et al, 2012), (Lake et al, 2011), (Babatunde et al, 2012).…”

supporting

confidence: 55%

Treatment outcome of pulmonary tuberculosis patients in a tertiary hospital in Bauchi Northeastern Nigeria

Jibrin¹

2017

jmms

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Pulmonary Tuberculosis (PTB) remains a major public health concern in both developing and developed countries, but the impact is much felt in sub-Saharan Africa and Asia, with high predisposing risk factor of co-morbidities of poverty, and high incidence of HIV. Information on the demographics and outcome is necessary for the control of the disease. The demographic characteristics and the treatment outcome of PTB have not been reported in Abubakar Tafawa Balewa Teaching Hospital (ATBUTH) Bauchi. Therefore, this study was aimed to describe the sociodemographic characteristics and determine the treatment outcome of the patients attending the Directly Observed Treatment Short course (DOTS) clinic at the institution. Demographic and outcome variables were extracted from the medical records and patient treatment by using a standard structured questionnaire and the results were express in percentages and frequencies. A total of two hundred and fifty nine (259) PTB patients records were extracted and entered into the study data base. Their Gender distribution was 146(56%) males and 113(44%) females age range of 15-70 years. Majority of the patient were civil servants with some level of education and earned less than thirty thousand (₦30,000) Naira, approximately sixty five dollars ($65) monthly. Most of them lived less than 5 Kilometres from the clinic. Eighty percent (80%) of patients were successfully treated while in 20% were not successfully treated. This study showed that pulmonary tuberculosis affects mostly the most productive age group of the population with some level of education and low income. The success rate of treatment falls short of the recommended success rate suggested by WHO. There is need for further studies to identify the factors responsible for failure to achieve the WHO recommendation as well as factors responsible for unsuccessful treatment.

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“…Male subjects had a higher morbidity rate of 62% compared to 38% in Females, which not obey the national sex pattern. The overall cure rate of 5 studied years (83.56%) in our patients was slightly lower than 85% recommended by the world health organization target [28,29]. This means that more effort in needed to further improve of this cure rate by efficacious measures for follow up of patients.…”

Section: Discussioncontrasting

confidence: 52%

Epidemiological study on tuberculosis patients in Ahvaz East Center during 2009- 2013

Karami

Harmooshi

Sharifi

2016

IJB

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To study TB incidence trend and its epidemiological aspects in recent years in Ahvaz East Center. As national and international Emphasis for detecting Smear positive pulmonary tuberculosis and eliminate the disease rate and global target internationally to eliminate TB by 2050 based on 1990 rate. In this cross – sectional descriptive-analytic study the records of all TB patients referred to Health centers and preventive diseases units in East of Ahvaz in 5 years (2009-2013) were evaluated. Data were derived from patients' records and entered to check lists and then analyzed using SPSS 17 software. During the studied years a total of 990 cases were reported by all centers and units under cover of Ahwaz Main East Health Center. Among them 232 cases (23.43%) was external pulmonary TB. Male subjects had a higher incidence of 62% compared to females. The age group between 25 - 45 year, was the most affected group. Smear positive rate varied from 58% to 76%. Cure rate in 5 studied years has not too differentiation, was varied 81% to 87%. The results show most affected TB cases in 5 studied years were pulmonary (73-84.5%), this obey the national pattern of the disease. Smear positive rate that varied from 58% to 76% was more than the national rate (53%). Morbidity in centers and units under cover of Ahwaz Main East Health Center was younger age pattern in compare to whole country rate. Incidence rate of TB was higher than national rate.

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Prevalence of Treatment Failure among Pulmonary Tuberculosis Patients in Federal Medical Centre, Gombe, Northeastern Nigeria

Cited by 14 publications

References 13 publications

Epidemiological characteristics and clinical outcome of HIV-related tuberculosis in a population of TB patients in South-Western Nigeria

Epidemiological characteristics and clinical outcome of HIV-related tuberculosis in a population of TB patients in South-Western Nigeria

Treatment outcome of pulmonary tuberculosis patients in a tertiary hospital in Bauchi Northeastern Nigeria

Epidemiological study on tuberculosis patients in Ahvaz East Center during 2009- 2013

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